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The map label for this gene is 15925161

Identifier: 15925161

GI number: 15925161

Start: 2311602

End: 2312789

Strand: Reverse

Name: 15925161

Synonym: SAV2171

Alternate gene names: NA

Gene position: 2312789-2311602 (Counterclockwise)

Preceding gene: 15925162

Following gene: 15925160

Centisome position: 80.35

GC content: 31.31

Gene sequence:

>1188_bases
ATGCTAGATAAAAATCAATTAGCTAAATATAAACAAGATCATTTGTGTGAATATGAAAAAATAATGAGTAACAATGAAAA
AGAAGCACTTGAAGAGAAGGTAGCGTCATTAGATTTAGATTTTATTGCCAAATTATATAACGATTTATACATCAATAAGA
AAACAATAGATGATGTATCTGCAGTTTCTGAAGTGAAATATGATATTAAATCACAAATGAGTGATGATGAGATTAAGCGT
TTAGAGGAACAAGGACTTCAAGCTATTAAAGAAGGACAATTTGCAGTACTTTTGATGGCAGGTGGTCAAGGAACAAGACT
TGGTTACAAGGGCCCTAAAGGTTCGTTTGAAATTGAAGGTGTAAGTTTATTTGAACTTCAAGCTAACCAATTAAAAACAT
TGAATCATCAATCTGGACATACGATTCAATGGTATATTATGACAAGTGATATCAATCATGAAGAAACTTTAGCTTATTTC
GAAGCACATAGTTATTTTGGATATGATCAAGAAGCAATCCATTTCTTTAAACAAGATAATATTGTGGCGCTTAGTGAAGA
AGGGAAGTTAATTTTAAATCAACAGGGTCGTATTATGGAAACGCCGAATGGTAATGGTGGCGTGTTTAAATCTTTAGACA
AGGCAGGATACTTAGAAGAAATGTCTAATAATGGCGTTAAGTATATTTTCTTGAATAATATCGACAATGTTTTAGTAAAA
GTGTTGGATCCACTATTTGCAGGATTTACGGTAGAACATGATTACGATATTACTTCTAAAACGATTCAACCAAAACCAGG
AGAAAGTGTTGGACGTTTAGTTAATGTCGATTGTAAAGATACAGTACTGGAGTATTCAGAATTAGATCCAGAAGTTGCAA
ATCAATTTAACAATGCTAATATCGGTATTCATGCATTTAAACTTGGTTTTATTTTAAACGCTGTAAATCGTGAGTTACCT
TATCATTTAGCTATTAAGAATTTGAAACAATTAGATGAGAACTTTGGGGTTATTGAACAACCAACTTTAAAATTCGAATT
GTTCTATTTTGACATATTTACTTATGGAACTAGTTTTGTCACGTTACAAGTTCCTAGAGAAGAAGAATTTTCACCTCTTA
AAAATAAAGAAGGTAAAGATAGTGTTGCAACTGCAACAGAAGATTTACGTAGAATGGGTTTAATTTAA

Upstream 100 bases:

>100_bases
TTATTTCAGCCTTTCATCAATGATATAATAAGCAACTGGAATACTAAGTTTTTATAGAAAATAAATTATTAAAGGTTACA
AACTCAGCAGGAGGCATAAA

Downstream 100 bases:

>100_bases
TGATAGGCGGTGACTATGATGTCCAAATCAACTAAAAAAAGTAATGACACAATCGTAGAAACATTTAAGGATATCATCCC
TTTATCATTTGGAGAAGAAA

Product: UDP-N-acetylglucosamine pyrophosphorylase

Products: diphosphate; UDP-N-acetyl-D-glucosamine

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKR
LEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYF
EAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVK
VLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELP
YHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI

Sequences:

>Translated_395_residues
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKR
LEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYF
EAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVK
VLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELP
YHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI
>Mature_395_residues
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKR
LEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYF
EAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVK
VLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELP
YHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI

Specific function: Unknown

COG id: COG4284

COG function: function code G; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 1 family [H]

Homologues:

Organism=Homo sapiens, GI187936958, Length=348, Percent_Identity=36.7816091954023, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI156627575, Length=344, Percent_Identity=36.6279069767442, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17552518, Length=400, Percent_Identity=31.75, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI193206427, Length=332, Percent_Identity=33.7349397590361, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6320100, Length=370, Percent_Identity=34.0540540540541, Blast_Score=195, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24582229, Length=422, Percent_Identity=35.0710900473934, Blast_Score=234, Evalue=7e-62,
Organism=Drosophila melanogaster, GI19920822, Length=422, Percent_Identity=35.0710900473934, Blast_Score=234, Evalue=8e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002618 [H]

Pfam domain/function: PF01704 UDPGP [H]

EC number: 2.7.7.23

Molecular weight: Translated: 44866; Mature: 44866

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVS
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHH
AVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEECC
VSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDN
EEEEEECHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
IVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVK
EEEECCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHH
VLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNAN
HHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCHHHHHCCCCCC
IGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFV
CEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCEEE
TLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVS
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHH
AVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEECC
VSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDN
EEEEEECHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
IVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVK
EEEECCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHH
VLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNAN
HHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCHHHHHCCCCCC
IGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFV
CEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCEEE
TLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UTP; N-acetyl-alpha-D-glucosamine 1-phosphate

Specific reaction: UTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-glucosamine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA