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The map label for this gene is dinB

Identifier: 15924885

GI number: 15924885

Start: 2034709

End: 2035779

Strand: Reverse

Name: dinB

Synonym: SAV1895

Alternate gene names: 15924885

Gene position: 2035779-2034709 (Counterclockwise)

Preceding gene: 15924886

Following gene: 15924882

Centisome position: 70.72

GC content: 34.45

Gene sequence:

>1071_bases
TTGACTGAGAGACGAATTATTCATATAGATATGGACTATTTTTTTGCACAAGTCGAAATGAGAGATAACCCCAAATTGAA
AGGGAAACCAGTCATTGTTGGTGGTAAAGCAAGCAGTAGGGGTGTTGTCTCTACGGCATCCTATGAAGCACGAAAATACG
GCGTCCATTCAGCAATGCCTATGTCACAAGCGCATAAATTATGTCCAAATGGATACTTTGTCACAAGTAATTTTGGTGCT
TACCGAGAAACATCTGCGCAGATTATGTCTATTTTCCGAAGTTATACAGATAAGGTAGAACCGATGTCATTGGATGAAGC
GTATTTAGATATTACAGAATTAGTGAGACCAGACCTTCCTGCTTCGAAAATTGCTCAGTATATTAGAAAAGATATTCTAG
AGCAGACACATTTAACAGCATCTGCAGGTGTTTCTTATAACAAATTTTTAGCTAAATTAGCGAGTGGTATGAATAAACCT
GATGGTTTGACTGTGATTGATTATCAAAATGTCCATGATATTTTGATGACATTGGATATTGGAGATTTTCCAGGCGTAGG
TAAAGCTTCCAAAAAAGTAATGCATGATAATGGTATTTTTAACGGTAGAGATTTATATGAGAAAACGGAATTTGAATTAA
TACGTTTGTTTGGAAAAAGAGGTCGGGGTTTATATAACAAGGCACGCGGTATTGACCATAGTGAAGTGAAATCATCAAGA
GTAAGAAAATCAGTAGGGACTGAACGCACATTTGCAACAGACGTGAATGATGATGAAGAGATTTTAAGAAAAGTATGGGA
ATTGTCAGGTAAAACAGCTGAACGTCTAAATAAATTACAGAAGTCAGCTAAAACTGTAACGGTTAAAATTAAAACTTATC
AATTTGAAACGCTATCTAAACAGATGAGTTTAAGAGATTCGGTTAGTTCTGAAGAAGATATTTATAATATTGCATATTTA
CTTTATAACGATTTAAAAGACCCAGATGTACCAATTCGACTTATTGGTGTCACTGTAGGTAATTTAGAACAATCAACTTA
TAAAAATATGACGATATATGACTTTATATAA

Upstream 100 bases:

>100_bases
CTAAGTGCAAGATTTATGTAAAAAAATCGTACACAGCGTATAATTATGTTGAGATATTTTTGTGCGTTATAAAAGTAAAA
ATTAGTAGGGAGGTGAGCAC

Downstream 100 bases:

>100_bases
AATAAAGCTCCCTGCAAAGTTTACATTTTTACAATGCTTACTTTTGAAGGGAGTATTTTATTTAGTCCTAGCCTTTATCT
TTTAGATTTTTACCATAAAT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGA
YRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKP
DGLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSR
VRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYL
LYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI

Sequences:

>Translated_356_residues
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGA
YRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKP
DGLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSR
VRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYL
LYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>Mature_355_residues
TERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAY
RETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPD
GLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRV
RKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLL
YNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=30.9734513274336, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=31.0650887573964, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI5729982, Length=349, Percent_Identity=29.7994269340974, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI154350220, Length=332, Percent_Identity=29.8192771084337, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI7705344, Length=126, Percent_Identity=46.031746031746, Blast_Score=112, Evalue=4e-25,
Organism=Escherichia coli, GI1786425, Length=298, Percent_Identity=45.9731543624161, Blast_Score=251, Evalue=4e-68,
Organism=Escherichia coli, GI1787432, Length=298, Percent_Identity=26.8456375838926, Blast_Score=88, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI193205700, Length=419, Percent_Identity=29.3556085918854, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17537959, Length=377, Percent_Identity=27.5862068965517, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI115534089, Length=393, Percent_Identity=26.972010178117, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI193205702, Length=364, Percent_Identity=26.6483516483516, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6324921, Length=206, Percent_Identity=30.0970873786408, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19923006, Length=412, Percent_Identity=26.6990291262136, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21355641, Length=285, Percent_Identity=29.4736842105263, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24644984, Length=285, Percent_Identity=29.4736842105263, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24668444, Length=356, Percent_Identity=26.123595505618, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_STAA1 (A7X420)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442470.1
- ProteinModelPortal:   A7X420
- SMR:   A7X420
- STRING:   A7X420
- EnsemblBacteria:   EBSTAT00000004902
- GeneID:   5559429
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1880
- eggNOG:   COG0389
- GeneTree:   EBGT00050000024172
- HOGENOM:   HBG734504
- OMA:   VICAASY
- ProtClustDB:   PRK02406
- BioCyc:   SAUR418127:SAHV_1880-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 40298; Mature: 40166

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMP
CCCCEEEEEEHHHEEEEEEECCCCCCCCCCEEEECCCCCCCCEEECCHHHHHHCCCCCCC
MSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLP
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
ASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGLTVIDYQNVHDILMTLDI
HHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEC
GDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSR
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHH
VRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSK
HHHHHCCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEEEEHHHHHH
QMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHCCCEEEECC
>Mature Secondary Structure 
TERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMP
CCCEEEEEEHHHEEEEEEECCCCCCCCCCEEEECCCCCCCCEEECCHHHHHHCCCCCCC
MSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLP
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
ASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGLTVIDYQNVHDILMTLDI
HHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEC
GDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSR
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHH
VRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSK
HHHHHCCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEEEEHHHHHH
QMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA