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The map label for this gene is esxA

Identifier: 15923272

GI number: 15923272

Start: 327030

End: 327323

Strand: Direct

Name: esxA

Synonym: SAV0282

Alternate gene names: 15923272

Gene position: 327030-327323 (Clockwise)

Preceding gene: 15923266

Following gene: 15923273

Centisome position: 11.36

GC content: 37.76

Gene sequence:

>294_bases
ATGGCAATGATTAAGATGAGTCCAGAGGAAATCAGAGCAAAATCGCAATCTTACGGGCAAGGTTCAGACCAAATCCGTCA
AATTTTATCTGATTTAACACGTGCACAAGGTGAAATTGCAGCGAACTGGGAAGGTCAAGCTTTCAGCCGTTTCGAAGAGC
AATTCCAACAACTTAGTCCTAAAGTAGAAAAATTTGCACAATTATTAGAAGAAATTAAACAACAATTGAATAGCACTGCT
GATGCCGTTCAAGAACAAGACCAACAACTTTCTAATAATTTCGGTTTGCAATAA

Upstream 100 bases:

>100_bases
ACTAATAATTTATATATTATTTGAGTAAGGAGCACTTTTTCAAAAAATAGTGTCCCTAAAAAGTTTTGATAAACTTAAAA
TATTCAGGAGGTTTCTAGTT

Downstream 100 bases:

>100_bases
GCATTCTGAAATTGGCAAAGTCACATTTTCTAATGTGGCTTTGCTTATCATTTTTTAAGAAAACAACTGAAAGGAAATAA
GCATGAAAAAGAAAAATTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MAMIKMSPEEIRAKSQSYGQGSDQIRQILSDLTRAQGEIAANWEGQAFSRFEEQFQQLSPKVEKFAQLLEEIKQQLNSTA
DAVQEQDQQLSNNFGLQ

Sequences:

>Translated_97_residues
MAMIKMSPEEIRAKSQSYGQGSDQIRQILSDLTRAQGEIAANWEGQAFSRFEEQFQQLSPKVEKFAQLLEEIKQQLNSTA
DAVQEQDQQLSNNFGLQ
>Mature_96_residues
AMIKMSPEEIRAKSQSYGQGSDQIRQILSDLTRAQGEIAANWEGQAFSRFEEQFQQLSPKVEKFAQLLEEIKQQLNSTAD
AVQEQDQQLSNNFGLQ

Specific function: Virulence factor that is important for the establishment of infection in the host

COG id: COG4842

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ESAT-6 (esx) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ESXA_STAAC (Q5HJ91)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_185166.1
- ProteinModelPortal:   Q5HJ91
- STRING:   Q5HJ91
- EnsemblBacteria:   EBSTAT00000008774
- GeneID:   3236675
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL0271
- TIGR:   SACOL0271
- eggNOG:   COG4842
- GeneTree:   EBGT00050000025401
- HOGENOM:   HBG341500
- OMA:   STIAEEW
- ProtClustDB:   CLSK884531
- BioCyc:   SAUR93062:SACOL0271-MONOMER
- GO:   GO:0009405
- InterPro:   IPR010310

Pfam domain/function: PF06013 WXG100

EC number: NA

Molecular weight: Translated: 11036; Mature: 10905

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMIKMSPEEIRAKSQSYGQGSDQIRQILSDLTRAQGEIAANWEGQAFSRFEEQFQQLSP
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCH
KVEKFAQLLEEIKQQLNSTADAVQEQDQQLSNNFGLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AMIKMSPEEIRAKSQSYGQGSDQIRQILSDLTRAQGEIAANWEGQAFSRFEEQFQQLSP
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCH
KVEKFAQLLEEIKQQLNSTADAVQEQDQQLSNNFGLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA