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The map label for this gene is bglA [H]

Identifier: 15923256

GI number: 15923256

Start: 309977

End: 311413

Strand: Direct

Name: bglA [H]

Synonym: SAV0266

Alternate gene names: 15923256

Gene position: 309977-311413 (Clockwise)

Preceding gene: 15923255

Following gene: 15923262

Centisome position: 10.77

GC content: 36.67

Gene sequence:

>1437_bases
ATGACAAAATTACCGCAAAATTTTATGTGGGGTGGCGCTCTTGCCGCAAATCAATTTGAAGGTGGATATGAAAAAGGTGG
TAAAGGGTTAAGTGTAATTGATGTTATGACGAGTGGTGCACATGGCAAAGCACGTCAGATTACAGAATCTATAGACCTCA
ATCACTATTATCCAAATCATGAAGGTATTGATTTTTATCATCGTTATAAGGAAGATATTGCCTTGTTTAAAGAAATGGGA
TTGAAATGTTTACGTACGTCGATTGCGTGGACACGTATCTTTCCGAATGGGGATGAAGATGTGCCAAATGAAGAAGGACT
TGCCTTTTATGATCGTATCTTTGATGAATTAATTGCACAAGGTATTGAACCTGTTGTGACGTTATCACATTTTGAGATGC
CACTTCATTTAGCGAAACATTATGGTGGATTTAGAAATAGAGAAGTTGTCGATTATTTTGTGCATTTTGCGCGTGTTGTA
TTTGAAAGATATAAAGATAAAGTTACATATTGGATGACGTTTAATGAAATTAATAATCAGATGGACACATCAAATCCTAT
CTTTTTATGGACGAATTCTGGGGTAGCATTGACAGAAAATGATAATCCTGAAGAAGTCTTGTATCAAGTAGCACATCATG
AACTTTTAGCCAGTGCTTTAGCAGTTCGTCTTGGTAAAGAGATTAATCCGAAGTTTAAGATTGGAACAATGATTTCACAT
GTACCCATTTATCCATATTCGTGTCATCCGAAAGATATGATGGAAGCACAAATTGCGAATCGCTTACGTTTCTTTTTCCC
GGATGTCCAAGTGAGAGGTTATTATCCAAGCTATGCTAAAAAAATGTTGGCACGAAAAGGATATGATGTTGGATGGCAAG
AAGGGGACGACAGTATTTTACAGCAGGGCACGGTTGATTATATTGGCTTTAGTTATTACATGTCTACGGCTGTAAAACAT
GATGTTGATACTACAGTTGAAAACAACATCGTCAACGGTGGTTTGAATCATTCTGTGGAGAATCCGCATATCGCAACGAG
TGATTGGGGTTGGGCGATTGATCCAGATGGCTTAAGATATACATTGAATGTGTTATATGATCGTTATCAGTTACCACTTT
TTATTGTGGAAAATGGTTTTGGTGCAGTTGATGAAGTGGTAGATGGACATATTCATGATGATTATCGCATTGAATATTTA
AAAGCACATATTACAGCAGCGATAGAAGCAGTTGATCAAGATGGTGTAGATTTAATCGGTTATACACCGTGGGGAATCAT
TGATATTGTTTCATTTACAACCGGTGAAATGAAGAAACGCTATGGTTTAATATATGTTGATCGAGATAATGATGGTCATG
GCACGATGGAACGCTTGAAAAAAGATTCGTTCTATTGGTATCAACAAGTGATAGCATCAAATGGAGATAAATTATAA

Upstream 100 bases:

>100_bases
CTCTGCCGATTTAGGAAAAGTAGAACTGACAATGAATGAAATCATTACGACTGAAGATGTTATTTTTAAAATATTTAAAA
ACTAGGAGTGTGTTGTAATA

Downstream 100 bases:

>100_bases
AGGTATATTATAAGTATTTTAGGGTTAGAGCCCGAGACATAAATTAATATAGTAGGACCTACAGTGTTATAATGGCGGGC
CCCCAACACAAAGAATTTCG

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MTKLPQNFMWGGALAANQFEGGYEKGGKGLSVIDVMTSGAHGKARQITESIDLNHYYPNHEGIDFYHRYKEDIALFKEMG
LKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVV
FERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISH
VPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDVGWQEGDDSILQQGTVDYIGFSYYMSTAVKH
DVDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYL
KAHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL

Sequences:

>Translated_478_residues
MTKLPQNFMWGGALAANQFEGGYEKGGKGLSVIDVMTSGAHGKARQITESIDLNHYYPNHEGIDFYHRYKEDIALFKEMG
LKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVV
FERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISH
VPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDVGWQEGDDSILQQGTVDYIGFSYYMSTAVKH
DVDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYL
KAHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
>Mature_477_residues
TKLPQNFMWGGALAANQFEGGYEKGGKGLSVIDVMTSGAHGKARQITESIDLNHYYPNHEGIDFYHRYKEDIALFKEMGL
KCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVF
ERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHV
PIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDVGWQEGDDSILQQGTVDYIGFSYYMSTAVKHD
VDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLK
AHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=494, Percent_Identity=28.3400809716599, Blast_Score=172, Evalue=9e-43,
Organism=Homo sapiens, GI110681710, Length=511, Percent_Identity=26.8101761252446, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI13273313, Length=489, Percent_Identity=25.7668711656442, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI24497614, Length=495, Percent_Identity=29.0909090909091, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI28376633, Length=489, Percent_Identity=26.5848670756646, Blast_Score=139, Evalue=8e-33,
Organism=Escherichia coli, GI2367174, Length=476, Percent_Identity=60.9243697478992, Blast_Score=611, Evalue=1e-176,
Organism=Escherichia coli, GI1789070, Length=483, Percent_Identity=49.0683229813665, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI2367270, Length=481, Percent_Identity=50.7276507276507, Blast_Score=470, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI17552856, Length=494, Percent_Identity=29.5546558704453, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17539390, Length=503, Percent_Identity=29.0258449304175, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI21356577, Length=469, Percent_Identity=26.0127931769723, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54739; Mature: 54608

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLPQNFMWGGALAANQFEGGYEKGGKGLSVIDVMTSGAHGKARQITESIDLNHYYPNH
CCCCCCCCCCCCCEECCCCCCCHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCC
EGIDFYHRYKEDIALFKEMGLKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHC
GIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQ
CCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHCCC
MDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISH
CCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHC
VPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDVGWQEGDDSIL
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHH
QQGTVDYIGFSYYMSTAVKHDVDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRY
HCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCEEEECCCCCEECCCCCEE
TLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLKAHITAAIEAVDQDGVDLIG
HHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
YTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
ECCCCHHHHHHCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TKLPQNFMWGGALAANQFEGGYEKGGKGLSVIDVMTSGAHGKARQITESIDLNHYYPNH
CCCCCCCCCCCCEECCCCCCCHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCC
EGIDFYHRYKEDIALFKEMGLKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHC
GIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQ
CCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHCCC
MDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISH
CCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHC
VPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDVGWQEGDDSIL
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHH
QQGTVDYIGFSYYMSTAVKHDVDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRY
HCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCEEEECCCCCEECCCCCEE
TLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLKAHITAAIEAVDQDGVDLIG
HHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
YTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
ECCCCHHHHHHCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]