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The map label for this gene is coa

Identifier: 15923220

GI number: 15923220

Start: 264636

End: 266612

Strand: Direct

Name: coa

Synonym: SAV0230

Alternate gene names: NA

Gene position: 264636-266612 (Clockwise)

Preceding gene: 15923218

Following gene: 15923226

Centisome position: 9.19

GC content: 34.7

Gene sequence:

>1977_bases
ATGAAAAAGCAAATAATTTCGCTAGGCGCATTAGCAGTTGCATCTAGCTTATTTACATGGGATAACAAAGCAGATGCGAT
AGTAACAAAGGATTATAGTAAAGAATCAAGAGTGAATGAGAAAAGTAAAAAGGGAGCTACTGTTTCAGATTATTACTATT
GGAAAATAATTGATAGTTTAGAGGCACAATTTACTGGAGCAATAGACTTATTGGAAGATTATAAATATGGAGATCCTATC
TATAAAGAAGCGAAAGATAGATTGATGACAAGAGTATTAGGAGAAGACCAGTATTTATTAAAGAAAAAGATTGATGAATA
TGAGCTTTATAAAAAGTGGTATAAAAGTTCAAATAAGAACACTAATATGCTTACTTTCCATAAATATAATCTTTACAATT
TAACAATGAATGAATATAACGATATTTTTAACTCTTTGAAAGATGCAGTTTATCAATTTAATAAAGAAGTTAAAGAAATA
GAGCATAAAAATGTTGACTTGAAGCAGTTTGATAAAGATGGAGAAGACAAGGCAACTAAAGAAGTTTATGACCTTGTTTC
TGAAATTGATACATTAGTTGTAACTTATTATGCTGATAAGGATTATGGGGAGCATGCGAAAGAGTTACGAGCAAAACTGG
ACTTAATCCTTGGAGATACAGACAATCCACATAAAATTACAAATGAGCGTATAAAAAAAGAAATGATCGATGACTTAAAT
TCAATTATAGATGATTTCTTTATGGAGACTAAACAAAATAGACCGAATTCTATAACAAAATATGATCCAACAAAACACAA
TTTTAAAGAGAAGAGTGAAAATAAACCTAATTTTGATAAATTAGTTGAAGAAACAAAAAAAGCAGTTAAAGAAGCAGACG
AATCTTGGAAAAATAAAACTGTCAAAAAATACGAGGAAACTGTAACAAAATCTCCTGTTGTAAAAGAAGAGAAGAAAGTT
GAAGAACCTCAATTACCTAAAGTTGGAAACCAGCAAGAGGTTAAAACTACGGCTGGTAAAGCTGAAGAAACAACACAACC
AGTGGCACAGCCATTAGTAAAAATTCCACAAGAAACAATCTATGGTGAAACTGTAAAAGGTCCAGAATATCCAACGATGG
AAAATAAAACGTTACAAGGTGAAATCGTTCAAGGTCCCGATTTTCTAACAATGGAACAAAACAGACCATCTTTAAGCGAT
AATTATACTCAACCGACGACACCGAACCCTATTTTAGAAGGTCTTGAAGGTAGCTCATCTAAACTTGAAATAAAACCACA
AGGTACTGAATCAACGTTGAAAGGTATTCAAGGAGAATCAAGTGATATTGAAGTTAAACCTCAAGCAACTGAAACAACAG
AAGCTTCTCAATATGGTCCGAGACCGCAATTTAACAAAACACCTAAGTATGTGAAATATAGAGATGCTGGTACAGGTATC
CGTGAATACAACGATGGAACATTTGGATATGAAGCGAGACCAAGATTCAACAAGCCAAGTGAAACAAATGCATACAACGT
AACGACAAATCAAGATGGCACAGTATCATACGGAGCTCGCCCAACACAAAACAAGCCAAGTGAAACAAACGCATATAACG
TAACAACACATGCAAATGGTCAAGTATCATACGGTGCTCGCCCAACACAAAAAAAGCCAAGCAAAACAAATGCATACAAC
GTAACAACACATGCAAATGGTCAAGTATCATATGGCGCTCGCCCGACACAAAAAAAGCCAAGCAAAACAAATGCATATAA
CGTAACAACACATGCAAATGGTCAAGTATCATACGGAGCTCGCCCGACATACAAGAAGCCAAGCGAAACAAATGCATACA
ACGTAACAACACATGCAAATGGTCAAGTATCATATGGCGCTCGCCCGACACAAAAAAAGCCAAGCGAAACAAACGCATAT
AACGTAACAACACATGCAGATGGTACTGCGACATATGGGCCTAGAGTAACAAAATAA

Upstream 100 bases:

>100_bases
AATGCTTTGTTTATTCTAGTTAATATATAGTTAATGTCTTTTAATATTTTGTTTCTTTAATGTAGATTGGGCAATTACAT
TTTGGAGGAATTAAAAAATT

Downstream 100 bases:

>100_bases
ATTTATAACTCTATCCAAAGACATACAGTCAATACAAAGAATTATGTATCTATACAACAGTAATCATGCATTCTATGATG
CTTCTAACTGAATTAAAGCA

Product: staphylocoagulase precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MKKQIISLGALAVASSLFTWDNKADAIVTKDYSKESRVNEKSKKGATVSDYYYWKIIDSLEAQFTGAIDLLEDYKYGDPI
YKEAKDRLMTRVLGEDQYLLKKKIDEYELYKKWYKSSNKNTNMLTFHKYNLYNLTMNEYNDIFNSLKDAVYQFNKEVKEI
EHKNVDLKQFDKDGEDKATKEVYDLVSEIDTLVVTYYADKDYGEHAKELRAKLDLILGDTDNPHKITNERIKKEMIDDLN
SIIDDFFMETKQNRPNSITKYDPTKHNFKEKSENKPNFDKLVEETKKAVKEADESWKNKTVKKYEETVTKSPVVKEEKKV
EEPQLPKVGNQQEVKTTAGKAEETTQPVAQPLVKIPQETIYGETVKGPEYPTMENKTLQGEIVQGPDFLTMEQNRPSLSD
NYTQPTTPNPILEGLEGSSSKLEIKPQGTESTLKGIQGESSDIEVKPQATETTEASQYGPRPQFNKTPKYVKYRDAGTGI
REYNDGTFGYEARPRFNKPSETNAYNVTTNQDGTVSYGARPTQNKPSETNAYNVTTHANGQVSYGARPTQKKPSKTNAYN
VTTHANGQVSYGARPTQKKPSKTNAYNVTTHANGQVSYGARPTYKKPSETNAYNVTTHANGQVSYGARPTQKKPSETNAY
NVTTHADGTATYGPRVTK

Sequences:

>Translated_658_residues
MKKQIISLGALAVASSLFTWDNKADAIVTKDYSKESRVNEKSKKGATVSDYYYWKIIDSLEAQFTGAIDLLEDYKYGDPI
YKEAKDRLMTRVLGEDQYLLKKKIDEYELYKKWYKSSNKNTNMLTFHKYNLYNLTMNEYNDIFNSLKDAVYQFNKEVKEI
EHKNVDLKQFDKDGEDKATKEVYDLVSEIDTLVVTYYADKDYGEHAKELRAKLDLILGDTDNPHKITNERIKKEMIDDLN
SIIDDFFMETKQNRPNSITKYDPTKHNFKEKSENKPNFDKLVEETKKAVKEADESWKNKTVKKYEETVTKSPVVKEEKKV
EEPQLPKVGNQQEVKTTAGKAEETTQPVAQPLVKIPQETIYGETVKGPEYPTMENKTLQGEIVQGPDFLTMEQNRPSLSD
NYTQPTTPNPILEGLEGSSSKLEIKPQGTESTLKGIQGESSDIEVKPQATETTEASQYGPRPQFNKTPKYVKYRDAGTGI
REYNDGTFGYEARPRFNKPSETNAYNVTTNQDGTVSYGARPTQNKPSETNAYNVTTHANGQVSYGARPTQKKPSKTNAYN
VTTHANGQVSYGARPTQKKPSKTNAYNVTTHANGQVSYGARPTYKKPSETNAYNVTTHANGQVSYGARPTQKKPSETNAY
NVTTHADGTATYGPRVTK
>Mature_658_residues
MKKQIISLGALAVASSLFTWDNKADAIVTKDYSKESRVNEKSKKGATVSDYYYWKIIDSLEAQFTGAIDLLEDYKYGDPI
YKEAKDRLMTRVLGEDQYLLKKKIDEYELYKKWYKSSNKNTNMLTFHKYNLYNLTMNEYNDIFNSLKDAVYQFNKEVKEI
EHKNVDLKQFDKDGEDKATKEVYDLVSEIDTLVVTYYADKDYGEHAKELRAKLDLILGDTDNPHKITNERIKKEMIDDLN
SIIDDFFMETKQNRPNSITKYDPTKHNFKEKSENKPNFDKLVEETKKAVKEADESWKNKTVKKYEETVTKSPVVKEEKKV
EEPQLPKVGNQQEVKTTAGKAEETTQPVAQPLVKIPQETIYGETVKGPEYPTMENKTLQGEIVQGPDFLTMEQNRPSLSD
NYTQPTTPNPILEGLEGSSSKLEIKPQGTESTLKGIQGESSDIEVKPQATETTEASQYGPRPQFNKTPKYVKYRDAGTGI
REYNDGTFGYEARPRFNKPSETNAYNVTTNQDGTVSYGARPTQNKPSETNAYNVTTHANGQVSYGARPTQKKPSKTNAYN
VTTHANGQVSYGARPTQKKPSKTNAYNVTTHANGQVSYGARPTYKKPSETNAYNVTTHANGQVSYGARPTQKKPSETNAY
NVTTHADGTATYGPRVTK

Specific function: Staphylocoagulase is an extracellular protein which specifically forms a complex with human prothrombin. This complex named staphylothrombin can clot fibrinogen without any proteolytic cleavage of prothrombin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the staphylocoagulase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014874
- InterPro:   IPR001443 [H]

Pfam domain/function: PF08764 Coagulase; PF04022 Staphylcoagulse [H]

EC number: NA

Molecular weight: Translated: 74520; Mature: 74520

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS00429 STAPHYLOCOAGULASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQIISLGALAVASSLFTWDNKADAIVTKDYSKESRVNEKSKKGATVSDYYYWKIIDSL
CCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHCCHHHHCCCEECCEEEEEEHHHH
EAQFTGAIDLLEDYKYGDPIYKEAKDRLMTRVLGEDQYLLKKKIDEYELYKKWYKSSNKN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHCCCCC
TNMLTFHKYNLYNLTMNEYNDIFNSLKDAVYQFNKEVKEIEHKNVDLKQFDKDGEDKATK
CCEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHH
EVYDLVSEIDTLVVTYYADKDYGEHAKELRAKLDLILGDTDNPHKITNERIKKEMIDDLN
HHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHH
SIIDDFFMETKQNRPNSITKYDPTKHNFKEKSENKPNFDKLVEETKKAVKEADESWKNKT
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VKKYEETVTKSPVVKEEKKVEEPQLPKVGNQQEVKTTAGKAEETTQPVAQPLVKIPQETI
HHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHHH
YGETVKGPEYPTMENKTLQGEIVQGPDFLTMEQNRPSLSDNYTQPTTPNPILEGLEGSSS
CCCCCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCC
KLEIKPQGTESTLKGIQGESSDIEVKPQATETTEASQYGPRPQFNKTPKYVKYRDAGTGI
EEEEECCCCHHHHHCCCCCCCCEEECCCCCCCCCHHHCCCCCCCCCCCCEEEEECCCCCC
REYNDGTFGYEARPRFNKPSETNAYNVTTNQDGTVSYGARPTQNKPSETNAYNVTTHANG
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCCCCEEEEECCCC
QVSYGARPTQKKPSKTNAYNVTTHANGQVSYGARPTQKKPSKTNAYNVTTHANGQVSYGA
EEECCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEEECCCCEEECCC
RPTYKKPSETNAYNVTTHANGQVSYGARPTQKKPSETNAYNVTTHADGTATYGPRVTK
CCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKKQIISLGALAVASSLFTWDNKADAIVTKDYSKESRVNEKSKKGATVSDYYYWKIIDSL
CCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHCCHHHHCCCEECCEEEEEEHHHH
EAQFTGAIDLLEDYKYGDPIYKEAKDRLMTRVLGEDQYLLKKKIDEYELYKKWYKSSNKN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHCCCCC
TNMLTFHKYNLYNLTMNEYNDIFNSLKDAVYQFNKEVKEIEHKNVDLKQFDKDGEDKATK
CCEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHH
EVYDLVSEIDTLVVTYYADKDYGEHAKELRAKLDLILGDTDNPHKITNERIKKEMIDDLN
HHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHH
SIIDDFFMETKQNRPNSITKYDPTKHNFKEKSENKPNFDKLVEETKKAVKEADESWKNKT
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VKKYEETVTKSPVVKEEKKVEEPQLPKVGNQQEVKTTAGKAEETTQPVAQPLVKIPQETI
HHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHHH
YGETVKGPEYPTMENKTLQGEIVQGPDFLTMEQNRPSLSDNYTQPTTPNPILEGLEGSSS
CCCCCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCC
KLEIKPQGTESTLKGIQGESSDIEVKPQATETTEASQYGPRPQFNKTPKYVKYRDAGTGI
EEEEECCCCHHHHHCCCCCCCCEEECCCCCCCCCHHHCCCCCCCCCCCCEEEEECCCCCC
REYNDGTFGYEARPRFNKPSETNAYNVTTNQDGTVSYGARPTQNKPSETNAYNVTTHANG
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCCCCEEEEECCCC
QVSYGARPTQKKPSKTNAYNVTTHANGQVSYGARPTQKKPSKTNAYNVTTHANGQVSYGA
EEECCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEEECCCCEEECCC
RPTYKKPSETNAYNVTTHANGQVSYGARPTQKKPSETNAYNVTTHADGTATYGPRVTK
CCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2587230; 3941089 [H]