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The map label for this gene is asd [H]

Identifier: 15921505

GI number: 15921505

Start: 1244292

End: 1245344

Strand: Direct

Name: asd [H]

Synonym: ST1242

Alternate gene names: 15921505

Gene position: 1244292-1245344 (Clockwise)

Preceding gene: 15921504

Following gene: 15921506

Centisome position: 46.17

GC content: 32.38

Gene sequence:

>1053_bases
GTGGCAGACAAAATAAAAGTTTCACTTCTAGGCTCTACTGGGATGGTAGGACAAAAAATGGTAAAAATGTTAGCAAAGCA
TCCCTATTTAGAGTTAGTAAAAGTTAGTGCTTCCCCTTCGAAAATTGGTAAAAAATATAAAGATGCAGTAAAGTGGATAG
AGCAAGGAGACATACCAGAAGAAGTACAAGATTTACCAATAGTTTCAACAAATTATGAAGATCATAAAGACGTTGATGTA
GTATTGTCAGCTTTACCAAATGAATTAGCAGAATCAATAGAACTTGAACTTGTGAAAAACGGAAAGATAGTTGTGTCTAA
TGCTAGTCCATTTAGAATGGACCCAGATGTACCATTAATTAACCCAGAAATTAATTGGGAACACCTAGAATTACTTAAAT
TTCAAAAGGAAAGAAAAGGTTGGAAAGGTATTCTAGTAAAAAATCCTAATTGTACAGCTGCTATAATGTCAATGCCAATA
AAACCCTTAATTGAAATAGCAACAAAATCTAAAATAATAATTACTACACTACAAGCAGTAAGTGGAGCTGGATATAATGG
AATATCATTTATGGCAATAGAGGGTAATATAATCCCATACATTAAAGGAGAAGAAGACAAAATAGCAAAAGAACTAACTA
AATTAAACGGAAAACTTGAAAATAATCAAATAATTCCAGCAAACTTAGACTCAACTGTTACATCAATTAGAGTACCTACA
AGAGTAGGACATATGGGAGTTATTAATATTGTTACAAATGAGAGAATCAACATAGAGGAAATAAAGAAAACACTAAAGAA
TTTTAAATCTTTACCTCAACAGAAAAATTTACCTACTGCACCAAAACAACCAATAATAGTAAGAGATGAAGAAGATAGAC
CACAGCCGATTATTGATGTAAATGCAGAAAGTGGCATGGCAGTAACTGTGGGCAGAATAAGACATGAAAATAACGTGCTT
AGGTTAGTCGTTTTAGGAGATAATTTAGTTAGAGGAGCTGCTGGAATAACAATACTTACTGTAGAAGTTATGAAAGAATT
AGGGTACATTTAG

Upstream 100 bases:

>100_bases
TTTTCATATCTAGAGGTCTGAAAGGCGTTAGCTTAACATTTATAGTTGATGAAAAAGATGAAAATAGTTTAGCCAAAGAA
CTTCATGAGGTGATCCTGGA

Downstream 100 bases:

>100_bases
ATGTTAAAGATAGATTTTCATGTTCATACCTATTATAGTGATGGAAAAGAGTCACCAAAAGAAATGTTAAATTATGCATT
AAAAGTTGGACTTAACGGAA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MADKIKVSLLGSTGMVGQKMVKMLAKHPYLELVKVSASPSKIGKKYKDAVKWIEQGDIPEEVQDLPIVSTNYEDHKDVDV
VLSALPNELAESIELELVKNGKIVVSNASPFRMDPDVPLINPEINWEHLELLKFQKERKGWKGILVKNPNCTAAIMSMPI
KPLIEIATKSKIIITTLQAVSGAGYNGISFMAIEGNIIPYIKGEEDKIAKELTKLNGKLENNQIIPANLDSTVTSIRVPT
RVGHMGVINIVTNERINIEEIKKTLKNFKSLPQQKNLPTAPKQPIIVRDEEDRPQPIIDVNAESGMAVTVGRIRHENNVL
RLVVLGDNLVRGAAGITILTVEVMKELGYI

Sequences:

>Translated_350_residues
MADKIKVSLLGSTGMVGQKMVKMLAKHPYLELVKVSASPSKIGKKYKDAVKWIEQGDIPEEVQDLPIVSTNYEDHKDVDV
VLSALPNELAESIELELVKNGKIVVSNASPFRMDPDVPLINPEINWEHLELLKFQKERKGWKGILVKNPNCTAAIMSMPI
KPLIEIATKSKIIITTLQAVSGAGYNGISFMAIEGNIIPYIKGEEDKIAKELTKLNGKLENNQIIPANLDSTVTSIRVPT
RVGHMGVINIVTNERINIEEIKKTLKNFKSLPQQKNLPTAPKQPIIVRDEEDRPQPIIDVNAESGMAVTVGRIRHENNVL
RLVVLGDNLVRGAAGITILTVEVMKELGYI
>Mature_349_residues
ADKIKVSLLGSTGMVGQKMVKMLAKHPYLELVKVSASPSKIGKKYKDAVKWIEQGDIPEEVQDLPIVSTNYEDHKDVDVV
LSALPNELAESIELELVKNGKIVVSNASPFRMDPDVPLINPEINWEHLELLKFQKERKGWKGILVKNPNCTAAIMSMPIK
PLIEIATKSKIIITTLQAVSGAGYNGISFMAIEGNIIPYIKGEEDKIAKELTKLNGKLENNQIIPANLDSTVTSIRVPTR
VGHMGVINIVTNERINIEEIKKTLKNFKSLPQQKNLPTAPKQPIIVRDEEDRPQPIIDVNAESGMAVTVGRIRHENNVLR
LVVLGDNLVRGAAGITILTVEVMKELGYI

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=359, Percent_Identity=37.0473537604457, Blast_Score=216, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38695; Mature: 38564

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKIKVSLLGSTGMVGQKMVKMLAKHPYLELVKVSASPSKIGKKYKDAVKWIEQGDIPE
CCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHH
EVQDLPIVSTNYEDHKDVDVVLSALPNELAESIELELVKNGKIVVSNASPFRMDPDVPLI
HHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHEEEEEEECCEEEEECCCCCEECCCCCEE
NPEINWEHLELLKFQKERKGWKGILVKNPNCTAAIMSMPIKPLIEIATKSKIIITTLQAV
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCHHHHHHHCCCEEEEEEEHHH
SGAGYNGISFMAIEGNIIPYIKGEEDKIAKELTKLNGKLENNQIIPANLDSTVTSIRVPT
CCCCCCCEEEEEEECCEEEEEECCHHHHHHHHHHHCCCCCCCEEEECCCCCCHHEEECCC
RVGHMGVINIVTNERINIEEIKKTLKNFKSLPQQKNLPTAPKQPIIVRDEEDRPQPIIDV
EECCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCEEEE
NAESGMAVTVGRIRHENNVLRLVVLGDNLVRGAAGITILTVEVMKELGYI
CCCCCCEEEEEEEECCCCEEEEEEECCCHHCCCCCEEEEEHHHHHHHCCC
>Mature Secondary Structure 
ADKIKVSLLGSTGMVGQKMVKMLAKHPYLELVKVSASPSKIGKKYKDAVKWIEQGDIPE
CCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHH
EVQDLPIVSTNYEDHKDVDVVLSALPNELAESIELELVKNGKIVVSNASPFRMDPDVPLI
HHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHEEEEEEECCEEEEECCCCCEECCCCCEE
NPEINWEHLELLKFQKERKGWKGILVKNPNCTAAIMSMPIKPLIEIATKSKIIITTLQAV
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCHHHHHHHCCCEEEEEEEHHH
SGAGYNGISFMAIEGNIIPYIKGEEDKIAKELTKLNGKLENNQIIPANLDSTVTSIRVPT
CCCCCCCEEEEEEECCEEEEEECCHHHHHHHHHHHCCCCCCCEEEECCCCCCHHEEECCC
RVGHMGVINIVTNERINIEEIKKTLKNFKSLPQQKNLPTAPKQPIIVRDEEDRPQPIIDV
EECCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCEEEE
NAESGMAVTVGRIRHENNVLRLVVLGDNLVRGAAGITILTVEVMKELGYI
CCCCCCEEEEEEEECCCCEEEEEEECCCHHCCCCCEEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]