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The map label for this gene is tgtA [H]

Identifier: 15920528

GI number: 15920528

Start: 349320

End: 349850

Strand: Reverse

Name: tgtA [H]

Synonym: ST0329

Alternate gene names: 15920528

Gene position: 349850-349320 (Counterclockwise)

Preceding gene: 15920529

Following gene: 15920527

Centisome position: 12.98

GC content: 29.38

Gene sequence:

>531_bases
ATGTTTAACTTAACTAAACCTTTAAAAGCACAAAAAGATGAAATAAATTATTTACGTTATATTGCAATGTATCAGTTTTC
TTCAAAAGTAGCTTCTTGTTTATTTCCAGAAGATTCTACATTTTTTATACAGAGATCATTAACTACTAATAGAATAAGAA
ATATTCTTACAGAAGATAAAAGATTATTCTTAGTATTAAGGGCACAAGATAATCTTTTCTCTATTACAGAAATAAGTGGA
CAAATTATAAAAAATTGTACTTCCCCTCCTTCATTTAGGTTTATTATTAAGAACGAGGTGGCTAGCTTTATTAGAGAAGG
AAGAAATGCTTTTTGTAAGTTCGTCATAAACTCTGATCCCAGTATTAGAGCTGGTGATGAAGTCTTAGTTGTTGATGAAC
AAGATAACTTGTTAGCTGTAGGAAGAGCAAAAGTCTCTGGTGAGGAAGTAAAACAATATAAAAGGGGATTAGCTGTAATT
GTAAAGAGAGGAATAAAAAATGTCTATCAAGATAATTCTAAAGGGAATTAG

Upstream 100 bases:

>100_bases
AATGGAAGAAAGTATGTTAACATGACTGATTTAATTACAGCTATAGAAAAAATTAAAGCTAAAAATAATAAAGCTAAAAA
TACTGACAGAACAGAAAAGT

Downstream 100 bases:

>100_bases
TGAAGATGAACTAAAAGGTGCTAAGTTTATTACCGGTTTTAGAACATTAGGTGAAGTAGGTTATATAGCTACTAGATATT
TAGTTTTAAAGTTAGGAATG

Product: hypothetical protein

Products: NA

Alternate protein names: Archaeal tRNA-guanine transglycosylase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MFNLTKPLKAQKDEINYLRYIAMYQFSSKVASCLFPEDSTFFIQRSLTTNRIRNILTEDKRLFLVLRAQDNLFSITEISG
QIIKNCTSPPSFRFIIKNEVASFIREGRNAFCKFVINSDPSIRAGDEVLVVDEQDNLLAVGRAKVSGEEVKQYKRGLAVI
VKRGIKNVYQDNSKGN

Sequences:

>Translated_176_residues
MFNLTKPLKAQKDEINYLRYIAMYQFSSKVASCLFPEDSTFFIQRSLTTNRIRNILTEDKRLFLVLRAQDNLFSITEISG
QIIKNCTSPPSFRFIIKNEVASFIREGRNAFCKFVINSDPSIRAGDEVLVVDEQDNLLAVGRAKVSGEEVKQYKRGLAVI
VKRGIKNVYQDNSKGN
>Mature_176_residues
MFNLTKPLKAQKDEINYLRYIAMYQFSSKVASCLFPEDSTFFIQRSLTTNRIRNILTEDKRLFLVLRAQDNLFSITEISG
QIIKNCTSPPSFRFIIKNEVASFIREGRNAFCKFVINSDPSIRAGDEVLVVDEQDNLLAVGRAKVSGEEVKQYKRGLAVI
VKRGIKNVYQDNSKGN

Specific function: Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs [H]

COG id: COG1370

COG function: function code O; Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PUA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002478
- InterPro:   IPR015947
- InterPro:   IPR002616 [H]

Pfam domain/function: PF01472 PUA; PF01702 TGT [H]

EC number: NA

Molecular weight: Translated: 20095; Mature: 20095

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50890 PUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNLTKPLKAQKDEINYLRYIAMYQFSSKVASCLFPEDSTFFIQRSLTTNRIRNILTEDK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCC
RLFLVLRAQDNLFSITEISGQIIKNCTSPPSFRFIIKNEVASFIREGRNAFCKFVINSDP
EEEEEEECCCCEEEHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCCEEEEEEECCCC
SIRAGDEVLVVDEQDNLLAVGRAKVSGEEVKQYKRGLAVIVKRGIKNVYQDNSKGN
CCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFNLTKPLKAQKDEINYLRYIAMYQFSSKVASCLFPEDSTFFIQRSLTTNRIRNILTEDK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCC
RLFLVLRAQDNLFSITEISGQIIKNCTSPPSFRFIIKNEVASFIREGRNAFCKFVINSDP
EEEEEEECCCCEEEHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCCEEEEEEECCCC
SIRAGDEVLVVDEQDNLLAVGRAKVSGEEVKQYKRGLAVIVKRGIKNVYQDNSKGN
CCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11121031 [H]