Click here to switch to the map view.

The map label for this gene is recQ [C]

Identifier: 15920324

GI number: 15920324

Start: 166094

End: 167959

Strand: Reverse

Name: recQ [C]

Synonym: ST0147

Alternate gene names: 15920324

Gene position: 167959-166094 (Counterclockwise)

Preceding gene: 15920327

Following gene: 15920323

Centisome position: 6.23

GC content: 37.73

Gene sequence:

>1866_bases
GTGAGTGAACTATTTACCCAATTCAAAAACTCTTACGTTTATGGTAAGAATTATCTAATAGTAGCTCCTACCGGATCTGG
CAAAACACATATTGCCAAGTATTTACTTAATGAGGAAAAAGGAATAGTAGTTTATACTTCACCACTAAAAGCTCTATCGA
GAGAAGTTTATAGAGCGACAAAGAGGAAAGCGAAATACGTAGATTCTGATGTATATGAAGATGATTTAAGATACTTATCT
GCAGAAGCATTGCTCACGACTTATGAGAAATTTGATAGCGCAATTAGACATGATTACAGTTGGTTAAAAAACATAAGCCT
CATAATCATTGACGAGATACATAATGTTGAAAGTGATAGAGGGTTAGGCATAGAGAACATAGTACTTTGGGCAAAAGAGA
ACTCAGTCCCGATAATAGGATTAAGTGCAACAGTAGGTAATGTGGAAGAATATAAGCAGTGGCTAAATTCGGAATTAATT
AAGGTGGAGAAAAGAAAAGTCCCGCTTCATGAATGCATAGCATTTCCTTATATAATTAAATGCTATGACAACAACAAGAT
TATACCCATTGAGAAAAGGAGGCTGAAAAACACCAAATTAGACCTACTCCTTGGCGTGTTAAGTTATATTCTGTCTTTAG
GAAAGAACGCATTAGTCTTCGTTAGGAGTAGAAACTCTGCAGAGACACTTGCCGAAACCCTTAGAAAGTTCTCAATACCA
GCCTTACCTTATCATTCCGGCTTACCTTATGATGTTAGAGATAAAGTAATAGAGTCTTTTATGAAGGGCGAAGTCAGGGT
GCTGGTATCTACAACAGCATTGGGTCAAGGAGTGAACTTACCCGTTTACGCTACAGTCTTTTATGATATCTCATTACCGG
ATTCAGATGATAAAGGAGAATTTAAAGGATGGAGAGATCTGTCAGTAGCAGAATTTAAGCAAATTGCCGGAAGGGCAGGA
AGACCGGGATTTGACCAAGAAGGAATGGCAATAGTTATAACAGAGACAATTAAGGAAATGGATAAGGTAGTGAAAACTTA
TTTCTCCTCATTTTTGGCAAAGAGTGAAGATATAAGTTTTAAGCTCGAGAACTTAACACTTGGTGTTATAAGCTGGTTCA
ATAGGAGGGAAGAAGAAGTTGAGGAGTTAATAGGTAAGGGATCGTTCACGTTTAAGGGGAAAGAAGTAAAACCGGCTATA
GAGTATCTGGTAAAACAGAACTTAGTGGAGAAAAGGGAAACGTTAAGGCTAACACCCTTAGGAAAGGCTGTGGCATTAAG
TTATATTGACGTATCTGCGTTAAATGGTTTTCCAGTAAACGTACAAGACTTCAATCCCCTCGACGTTGTATACTCATCAC
CAGCTGTGCTACAGTCATTAAGGGGATGTGAGGAAGGAAAAGAACTCATTGAGAGATGGGTTAATGGAGGAGATATAGCA
TCTCTCTGCCTAAAGCTTTCGGCAAAAGATATTGATGATGTAATTTCAAACGCCAGATGGATAGCCTTTGCTCTTTATAG
AGTATTAAGAGCATTAAACCATCCAAAGGCGAAGGAAGCCCTTGAGTTTTATGAAAGGGTAAAATACGGCTTACCGAAGG
AGGGAATAGAAATGATGAAAGCTGGATTATCTAGGGATGAGGCTAAAAAACTTCTCCAATTAAATATTAAGAGCGTAGAT
GAAGCATGCATCATGAAGGATATACTTAATATTGACGGGATTGAGTGCAGAAAGTTCCATGAAGAATTAAGAAGATTTGT
TAACGAGAACTTCGGGAAAGATATTGACCAAAACGATCCCAGAGTTGAGATTTTAAAAAGGTTCGGAATAATTGTCGAGA
CCGGATGGAAAAAATATGGAAAATAA

Upstream 100 bases:

>100_bases
GGTCACAAGCAATATAAAACTTAACCATTTCTACATTACGTTACCATCATAAGTGTAAAGAAAGTAAATCAATTATAACC
TTTTACACTTTATATCCTTT

Downstream 100 bases:

>100_bases
GAGTAAAGTTATCGCATCGGTTTATTTAGTGTACTAAAACCTAGTAATACTGTGAAAACTTACATAGACAATATAGATAA
AATTACTGCATTCTCTAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MSELFTQFKNSYVYGKNYLIVAPTGSGKTHIAKYLLNEEKGIVVYTSPLKALSREVYRATKRKAKYVDSDVYEDDLRYLS
AEALLTTYEKFDSAIRHDYSWLKNISLIIIDEIHNVESDRGLGIENIVLWAKENSVPIIGLSATVGNVEEYKQWLNSELI
KVEKRKVPLHECIAFPYIIKCYDNNKIIPIEKRRLKNTKLDLLLGVLSYILSLGKNALVFVRSRNSAETLAETLRKFSIP
ALPYHSGLPYDVRDKVIESFMKGEVRVLVSTTALGQGVNLPVYATVFYDISLPDSDDKGEFKGWRDLSVAEFKQIAGRAG
RPGFDQEGMAIVITETIKEMDKVVKTYFSSFLAKSEDISFKLENLTLGVISWFNRREEEVEELIGKGSFTFKGKEVKPAI
EYLVKQNLVEKRETLRLTPLGKAVALSYIDVSALNGFPVNVQDFNPLDVVYSSPAVLQSLRGCEEGKELIERWVNGGDIA
SLCLKLSAKDIDDVISNARWIAFALYRVLRALNHPKAKEALEFYERVKYGLPKEGIEMMKAGLSRDEAKKLLQLNIKSVD
EACIMKDILNIDGIECRKFHEELRRFVNENFGKDIDQNDPRVEILKRFGIIVETGWKKYGK

Sequences:

>Translated_621_residues
MSELFTQFKNSYVYGKNYLIVAPTGSGKTHIAKYLLNEEKGIVVYTSPLKALSREVYRATKRKAKYVDSDVYEDDLRYLS
AEALLTTYEKFDSAIRHDYSWLKNISLIIIDEIHNVESDRGLGIENIVLWAKENSVPIIGLSATVGNVEEYKQWLNSELI
KVEKRKVPLHECIAFPYIIKCYDNNKIIPIEKRRLKNTKLDLLLGVLSYILSLGKNALVFVRSRNSAETLAETLRKFSIP
ALPYHSGLPYDVRDKVIESFMKGEVRVLVSTTALGQGVNLPVYATVFYDISLPDSDDKGEFKGWRDLSVAEFKQIAGRAG
RPGFDQEGMAIVITETIKEMDKVVKTYFSSFLAKSEDISFKLENLTLGVISWFNRREEEVEELIGKGSFTFKGKEVKPAI
EYLVKQNLVEKRETLRLTPLGKAVALSYIDVSALNGFPVNVQDFNPLDVVYSSPAVLQSLRGCEEGKELIERWVNGGDIA
SLCLKLSAKDIDDVISNARWIAFALYRVLRALNHPKAKEALEFYERVKYGLPKEGIEMMKAGLSRDEAKKLLQLNIKSVD
EACIMKDILNIDGIECRKFHEELRRFVNENFGKDIDQNDPRVEILKRFGIIVETGWKKYGK
>Mature_620_residues
SELFTQFKNSYVYGKNYLIVAPTGSGKTHIAKYLLNEEKGIVVYTSPLKALSREVYRATKRKAKYVDSDVYEDDLRYLSA
EALLTTYEKFDSAIRHDYSWLKNISLIIIDEIHNVESDRGLGIENIVLWAKENSVPIIGLSATVGNVEEYKQWLNSELIK
VEKRKVPLHECIAFPYIIKCYDNNKIIPIEKRRLKNTKLDLLLGVLSYILSLGKNALVFVRSRNSAETLAETLRKFSIPA
LPYHSGLPYDVRDKVIESFMKGEVRVLVSTTALGQGVNLPVYATVFYDISLPDSDDKGEFKGWRDLSVAEFKQIAGRAGR
PGFDQEGMAIVITETIKEMDKVVKTYFSSFLAKSEDISFKLENLTLGVISWFNRREEEVEELIGKGSFTFKGKEVKPAIE
YLVKQNLVEKRETLRLTPLGKAVALSYIDVSALNGFPVNVQDFNPLDVVYSSPAVLQSLRGCEEGKELIERWVNGGDIAS
LCLKLSAKDIDDVISNARWIAFALYRVLRALNHPKAKEALEFYERVKYGLPKEGIEMMKAGLSRDEAKKLLQLNIKSVDE
ACIMKDILNIDGIECRKFHEELRRFVNENFGKDIDQNDPRVEILKRFGIIVETGWKKYGK

Specific function: Involved In The Recf Recombination Pathway; Its Gene Expression Is Under The Regulation Of The Sos System. It Is A DNA Helicase. [C]

COG id: COG1204

COG function: function code R; Superfamily II helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI76880486, Length=424, Percent_Identity=28.5377358490566, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI40217847, Length=381, Percent_Identity=28.6089238845144, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI169218225, Length=381, Percent_Identity=28.3464566929134, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI130484567, Length=392, Percent_Identity=26.530612244898, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI222831595, Length=155, Percent_Identity=30.3225806451613, Blast_Score=69, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17537519, Length=497, Percent_Identity=27.364185110664, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17542826, Length=405, Percent_Identity=24.6913580246914, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71995032, Length=384, Percent_Identity=24.4791666666667, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI133930973, Length=165, Percent_Identity=29.0909090909091, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321710, Length=391, Percent_Identity=27.1099744245524, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI9755332, Length=387, Percent_Identity=27.390180878553, Blast_Score=114, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6321020, Length=402, Percent_Identity=30.0995024875622, Blast_Score=106, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6323430, Length=177, Percent_Identity=30.5084745762712, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24647182, Length=417, Percent_Identity=29.7362110311751, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR022965
- InterPro:   IPR003583 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 70631; Mature: 70500

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS00690 DEAH_ATP_HELICASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELFTQFKNSYVYGKNYLIVAPTGSGKTHIAKYLLNEEKGIVVYTSPLKALSREVYRAT
CCHHHHHHHCCEEECCEEEEEEECCCCHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHH
KRKAKYVDSDVYEDDLRYLSAEALLTTYEKFDSAIRHDYSWLKNISLIIIDEIHNVESDR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHCCCCCC
GLGIENIVLWAKENSVPIIGLSATVGNVEEYKQWLNSELIKVEKRKVPLHECIAFPYIIK
CCCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEE
CYDNNKIIPIEKRRLKNTKLDLLLGVLSYILSLGKNALVFVRSRNSAETLAETLRKFSIP
EECCCEEEECHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCC
ALPYHSGLPYDVRDKVIESFMKGEVRVLVSTTALGQGVNLPVYATVFYDISLPDSDDKGE
CCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCEEEEEEEEEECCCCCCCCC
FKGWRDLSVAEFKQIAGRAGRPGFDQEGMAIVITETIKEMDKVVKTYFSSFLAKSEDISF
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEE
KLENLTLGVISWFNRREEEVEELIGKGSFTFKGKEVKPAIEYLVKQNLVEKRETLRLTPL
EEECHHHHHHHHHCCCHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHEEECCC
GKAVALSYIDVSALNGFPVNVQDFNPLDVVYSSPAVLQSLRGCEEGKELIERWVNGGDIA
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHCHHHHHHHHHHHCCCCHHH
SLCLKLSAKDIDDVISNARWIAFALYRVLRALNHPKAKEALEFYERVKYGLPKEGIEMMK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHH
AGLSRDEAKKLLQLNIKSVDEACIMKDILNIDGIECRKFHEELRRFVNENFGKDIDQNDP
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
RVEILKRFGIIVETGWKKYGK
HHHHHHHCCCEEECCHHHCCC
>Mature Secondary Structure 
SELFTQFKNSYVYGKNYLIVAPTGSGKTHIAKYLLNEEKGIVVYTSPLKALSREVYRAT
CHHHHHHHCCEEECCEEEEEEECCCCHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHH
KRKAKYVDSDVYEDDLRYLSAEALLTTYEKFDSAIRHDYSWLKNISLIIIDEIHNVESDR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHCCCCCC
GLGIENIVLWAKENSVPIIGLSATVGNVEEYKQWLNSELIKVEKRKVPLHECIAFPYIIK
CCCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEE
CYDNNKIIPIEKRRLKNTKLDLLLGVLSYILSLGKNALVFVRSRNSAETLAETLRKFSIP
EECCCEEEECHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCC
ALPYHSGLPYDVRDKVIESFMKGEVRVLVSTTALGQGVNLPVYATVFYDISLPDSDDKGE
CCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCEEEEEEEEEECCCCCCCCC
FKGWRDLSVAEFKQIAGRAGRPGFDQEGMAIVITETIKEMDKVVKTYFSSFLAKSEDISF
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEE
KLENLTLGVISWFNRREEEVEELIGKGSFTFKGKEVKPAIEYLVKQNLVEKRETLRLTPL
EEECHHHHHHHHHCCCHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHEEECCC
GKAVALSYIDVSALNGFPVNVQDFNPLDVVYSSPAVLQSLRGCEEGKELIERWVNGGDIA
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHCHHHHHHHHHHHCCCCHHH
SLCLKLSAKDIDDVISNARWIAFALYRVLRALNHPKAKEALEFYERVKYGLPKEGIEMMK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHH
AGLSRDEAKKLLQLNIKSVDEACIMKDILNIDGIECRKFHEELRRFVNENFGKDIDQNDP
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
RVEILKRFGIIVETGWKKYGK
HHHHHHHCCCEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]