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The map label for this gene is fadE [H]

Identifier: 15920265

GI number: 15920265

Start: 108841

End: 109923

Strand: Reverse

Name: fadE [H]

Synonym: ST0087

Alternate gene names: 15920265

Gene position: 109923-108841 (Counterclockwise)

Preceding gene: 15920266

Following gene: 15920264

Centisome position: 4.08

GC content: 34.72

Gene sequence:

>1083_bases
ATGAATGAAGACGAATATAGGCAAAAATTAAGGGAATGGATAAGCCAGAACGCTCCCAGAAATCTTATGGGTAAAAAAAT
CCTTTTTGATACTGCTGAGATAGACAATTATGAGGAGTTAAGGAATTGGCAAAGGAAACTTTATGAAGCCGGATATTTAG
GAATAACTTGGCCTAAAGAGTATGGAGGTCAAGGTTTAGATCCTATTTATGAGATAATAGCTTACGAAGAGTTTATTAGG
GCTGGATTACCTTATGGTAGAAGTTTAGGTTCAATAGGTCTAATGGTCGCTGGACCAGCAATCCTTAAACATGGAAGTGA
AGAACAAAAGAAAAAATACCTTAAAAGAATCCTTTCAGCTGAGGATATCTGGTGTCAAGGTTTTTCTGAGCCTCATGCAG
GTTCTGATTTGGCAAATATTAAGACAAGGGCTGAAGATAAAGGAGAATACTTCGAAATAAATGGTCAAAAAATTTGGAGT
AGTTATGCTCACTTAGCTAACTATATGTTACTTTTAGCAAGAACTGGAGAAGACAAATACAAGGGGCTTACAATGTTTAT
AGTTGATATGAAACAAGAGGGGATAAAAGTCTCACCAATAACCCAAATTACTGGTAAAAGTGAATTTAACGTAGTTTATT
TAAATAGCGTAAAAGTACCTAAAGAAAATATAGTTGGTAAAGTTGGTGAGGGATGGAATGTTGCAATGACTGTTCTTAAT
CACGAGAGATTCTTCTTAGGAGTAACAATGTTATTTGTATCTAAAATACTTCTAGAGAAATTACGTGTTAAAGAATTAGA
AGAAGAAATAAAAGGACTAGAAGCATTCTACAAAAGACTCCTTGTAAAGATAAGAAAGGGAGAAGAAGAAATTGATGTAG
AAGGTGCCGTTTTAAAGTTGGTCTCATCAGAGATTTTACAGAGGATTTATGAAATAGCAGTATCCCAATACGATTTAGAG
ACTATTATGGAGGATACTTGGTATTTAGGCATGTTAGCTTCTAGGGGAAGAACGATTGCCGGTGGTACATCAGAAATATT
GAGAAATTTAATAGGCGAGAGACTACTAAAATTACCGAAATAA

Upstream 100 bases:

>100_bases
CCAACTCCTATTGAGATTATAGGATCTGCTATCACTTTAATAGGAGTTTATCTGACAATGACATCTTAAGAAATTTATTT
TTGAACTCTAAAATAATTTT

Downstream 100 bases:

>100_bases
ATATTAGAAAGAGAATTAAATGAAGTATTTATGTATTTTGAGGATTTCCAAGTAGGGCAGAAGTGGGAAAGTAAGGGAAG
GACTGTAACAGAAGCAGATG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MNEDEYRQKLREWISQNAPRNLMGKKILFDTAEIDNYEELRNWQRKLYEAGYLGITWPKEYGGQGLDPIYEIIAYEEFIR
AGLPYGRSLGSIGLMVAGPAILKHGSEEQKKKYLKRILSAEDIWCQGFSEPHAGSDLANIKTRAEDKGEYFEINGQKIWS
SYAHLANYMLLLARTGEDKYKGLTMFIVDMKQEGIKVSPITQITGKSEFNVVYLNSVKVPKENIVGKVGEGWNVAMTVLN
HERFFLGVTMLFVSKILLEKLRVKELEEEIKGLEAFYKRLLVKIRKGEEEIDVEGAVLKLVSSEILQRIYEIAVSQYDLE
TIMEDTWYLGMLASRGRTIAGGTSEILRNLIGERLLKLPK

Sequences:

>Translated_360_residues
MNEDEYRQKLREWISQNAPRNLMGKKILFDTAEIDNYEELRNWQRKLYEAGYLGITWPKEYGGQGLDPIYEIIAYEEFIR
AGLPYGRSLGSIGLMVAGPAILKHGSEEQKKKYLKRILSAEDIWCQGFSEPHAGSDLANIKTRAEDKGEYFEINGQKIWS
SYAHLANYMLLLARTGEDKYKGLTMFIVDMKQEGIKVSPITQITGKSEFNVVYLNSVKVPKENIVGKVGEGWNVAMTVLN
HERFFLGVTMLFVSKILLEKLRVKELEEEIKGLEAFYKRLLVKIRKGEEEIDVEGAVLKLVSSEILQRIYEIAVSQYDLE
TIMEDTWYLGMLASRGRTIAGGTSEILRNLIGERLLKLPK
>Mature_360_residues
MNEDEYRQKLREWISQNAPRNLMGKKILFDTAEIDNYEELRNWQRKLYEAGYLGITWPKEYGGQGLDPIYEIIAYEEFIR
AGLPYGRSLGSIGLMVAGPAILKHGSEEQKKKYLKRILSAEDIWCQGFSEPHAGSDLANIKTRAEDKGEYFEINGQKIWS
SYAHLANYMLLLARTGEDKYKGLTMFIVDMKQEGIKVSPITQITGKSEFNVVYLNSVKVPKENIVGKVGEGWNVAMTVLN
HERFFLGVTMLFVSKILLEKLRVKELEEEIKGLEAFYKRLLVKIRKGEEEIDVEGAVLKLVSSEILQRIYEIAVSQYDLE
TIMEDTWYLGMLASRGRTIAGGTSEILRNLIGERLLKLPK

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=271, Percent_Identity=30.6273062730627, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI21361497, Length=231, Percent_Identity=36.7965367965368, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI226958414, Length=268, Percent_Identity=30.9701492537313, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4557235, Length=241, Percent_Identity=34.4398340248963, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI76496475, Length=241, Percent_Identity=34.4398340248963, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI4501859, Length=238, Percent_Identity=31.9327731092437, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI4557231, Length=288, Percent_Identity=30.5555555555556, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI187960098, Length=288, Percent_Identity=30.5555555555556, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI4557233, Length=369, Percent_Identity=27.6422764227642, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI7669494, Length=246, Percent_Identity=25.609756097561, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4503943, Length=246, Percent_Identity=26.0162601626016, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4501857, Length=343, Percent_Identity=23.3236151603499, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7656849, Length=239, Percent_Identity=25.1046025104602, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87081958, Length=243, Percent_Identity=30.0411522633745, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786223, Length=209, Percent_Identity=25.8373205741627, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=250, Percent_Identity=34.8, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17508101, Length=258, Percent_Identity=31.3953488372093, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71982178, Length=210, Percent_Identity=33.8095238095238, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=223, Percent_Identity=31.8385650224215, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=403, Percent_Identity=25.0620347394541, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=228, Percent_Identity=33.7719298245614, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=268, Percent_Identity=29.8507462686567, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=324, Percent_Identity=27.4691358024691, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=211, Percent_Identity=31.2796208530806, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985192, Length=242, Percent_Identity=30.1652892561983, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71990804, Length=223, Percent_Identity=29.5964125560538, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=228, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=226, Percent_Identity=26.9911504424779, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17531909, Length=114, Percent_Identity=38.5964912280702, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=207, Percent_Identity=30.4347826086957, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17533517, Length=211, Percent_Identity=28.436018957346, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21355753, Length=255, Percent_Identity=35.6862745098039, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21356377, Length=260, Percent_Identity=30.7692307692308, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281363737, Length=234, Percent_Identity=35.042735042735, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24660351, Length=367, Percent_Identity=27.7929155313352, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24666513, Length=210, Percent_Identity=32.8571428571429, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646207, Length=259, Percent_Identity=28.1853281853282, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19920834, Length=255, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41222; Mature: 41222

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEDEYRQKLREWISQNAPRNLMGKKILFDTAEIDNYEELRNWQRKLYEAGYLGITWPKE
CCHHHHHHHHHHHHHCCCCHHHHCCHHEEECCCCCCHHHHHHHHHHHHHCCCCEEECCHH
YGGQGLDPIYEIIAYEEFIRAGLPYGRSLGSIGLMVAGPAILKHGSEEQKKKYLKRILSA
HCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHCC
EDIWCQGFSEPHAGSDLANIKTRAEDKGEYFEINGQKIWSSYAHLANYMLLLARTGEDKY
CHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHEECCCHHH
KGLTMFIVDMKQEGIKVSPITQITGKSEFNVVYLNSVKVPKENIVGKVGEGWNVAMTVLN
CCEEEEEEEECCCCEEECCCCEECCCCCEEEEEEECCCCCHHHHCCCCCCCCEEEEEECC
HERFFLGVTMLFVSKILLEKLRVKELEEEIKGLEAFYKRLLVKIRKGEEEIDVEGAVLKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHH
VSSEILQRIYEIAVSQYDLETIMEDTWYLGMLASRGRTIAGGTSEILRNLIGERLLKLPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNEDEYRQKLREWISQNAPRNLMGKKILFDTAEIDNYEELRNWQRKLYEAGYLGITWPKE
CCHHHHHHHHHHHHHCCCCHHHHCCHHEEECCCCCCHHHHHHHHHHHHHCCCCEEECCHH
YGGQGLDPIYEIIAYEEFIRAGLPYGRSLGSIGLMVAGPAILKHGSEEQKKKYLKRILSA
HCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHCC
EDIWCQGFSEPHAGSDLANIKTRAEDKGEYFEINGQKIWSSYAHLANYMLLLARTGEDKY
CHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHEECCCHHH
KGLTMFIVDMKQEGIKVSPITQITGKSEFNVVYLNSVKVPKENIVGKVGEGWNVAMTVLN
CCEEEEEEEECCCCEEECCCCEECCCCCEEEEEEECCCCCHHHHCCCCCCCCEEEEEECC
HERFFLGVTMLFVSKILLEKLRVKELEEEIKGLEAFYKRLLVKIRKGEEEIDVEGAVLKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHH
VSSEILQRIYEIAVSQYDLETIMEDTWYLGMLASRGRTIAGGTSEILRNLIGERLLKLPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]