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The map label for this gene is obgE

Identifier: 159185379

GI number: 159185379

Start: 2785977

End: 2787044

Strand: Reverse

Name: obgE

Synonym: Atu2781

Alternate gene names: 159185379

Gene position: 2787044-2785977 (Counterclockwise)

Preceding gene: 159185380

Following gene: 15890029

Centisome position: 98.08

GC content: 59.36

Gene sequence:

>1068_bases
ATGAAATTTCTCGATGAAGCAAAAGTCTATATCAAGTCCGGTGATGGCGGCGCGGGCGCCGTGTCGTTCCGGCGCGAAAA
ATTCATCGAGTTCGGCGGCCCTGACGGCGGTGATGGCGGACGCGGCGGCGACGTCTGGGTGGAAGTGGTCAATGGCCTTA
ACACGCTGATCGACTTTCGCTTCCAGCAGCATTTCAAGGCTTCTATCGGACAGCATGGCATGGGCAAGACCCGCACCGGT
GCCAAGGGTTCGGATGTCGTGCTGAAAGTGCCTGTTGGTACCCAGATTTTCGAGGAAGACAATGAAACGCTGATCATGGA
CCTTACGAAGGAAGGTCAGCGCTTTCGTCTTGCTGCCGGCGGCAATGGCGGTTTCGGCAATGCCTACTTCAAGTCGTCCA
CCAATCAGGCGCCTACCCATGCCAATCCGGGCCTGGCAGGTGAGGAAAAAACCATCTGGCTGCGGCTTAAGCTGATTGCT
GATGCCGGTCTCGTTGGTCTGCCGAATGCGGGTAAATCCACATTCCTGGCGACCGTGACCCGTGCGCGTCCGAAGATCGC
CAATTATCCCTTTACCACGCTGCATCCCAACCTTGGCGTTGCGACCATCGACGGTCGTGAATTCGTGCTGGCCGACATTC
CCGGTCTTATCGAAGGCGCGCATGAGGGTGTGGGCATCGGCGACCGCTTCCTCGGCCACGTGGAGCGCACGCGTGTGCTG
CTGCACCTCGTCTCCGCCCAGGAAGAAAAAGTCGGCAAGGCCTATAAGACGGTCAAGGCCGAGCTGGATGCTTACGGCGG
CGGGCTGACCGACAAGCCGGAAATCGTGGCGCTGTCGCAGATTGACGTGCTGGACGAGAAAGAACTGAAGAAAAAGGCTA
AGGAACTGGAAAAGGCCTGCGGCCGTCCGCCGCTCCTGCTATCCGCTGCCGCCCATATCGGCATGACGGAAGCACTGCGC
GCCCTTCGCGACATCATCGTTTCGGCAAGCAATGGCGGCGACACCGCCCTTCCAGACCGGTCGATGCCGCATGAGAGCGA
GGTCGAGGAAGAGGACGACCGCCTATGA

Upstream 100 bases:

>100_bases
TTGACCTCGTGAAGAAGCGCTTGTATTCGAAACGACGATATTTTTGTTTGGCGCGGCACGATTGGTTGGTGCGCCCGCAA
ACCGACAGAACGGCAGTCCG

Downstream 100 bases:

>100_bases
GCCTGACGCGCAAGCCGCTGGCGAGCCACCACCGGATCGTCATCAAGATCGGTTCGGCGCTTCTGGTGGACCGGAAAAGC
GGCCTGAAGAAAGACTGGCT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKFLDEAKVYIKSGDGGAGAVSFRREKFIEFGGPDGGDGGRGGDVWVEVVNGLNTLIDFRFQQHFKASIGQHGMGKTRTG
AKGSDVVLKVPVGTQIFEEDNETLIMDLTKEGQRFRLAAGGNGGFGNAYFKSSTNQAPTHANPGLAGEEKTIWLRLKLIA
DAGLVGLPNAGKSTFLATVTRARPKIANYPFTTLHPNLGVATIDGREFVLADIPGLIEGAHEGVGIGDRFLGHVERTRVL
LHLVSAQEEKVGKAYKTVKAELDAYGGGLTDKPEIVALSQIDVLDEKELKKKAKELEKACGRPPLLLSAAAHIGMTEALR
ALRDIIVSASNGGDTALPDRSMPHESEVEEEDDRL

Sequences:

>Translated_355_residues
MKFLDEAKVYIKSGDGGAGAVSFRREKFIEFGGPDGGDGGRGGDVWVEVVNGLNTLIDFRFQQHFKASIGQHGMGKTRTG
AKGSDVVLKVPVGTQIFEEDNETLIMDLTKEGQRFRLAAGGNGGFGNAYFKSSTNQAPTHANPGLAGEEKTIWLRLKLIA
DAGLVGLPNAGKSTFLATVTRARPKIANYPFTTLHPNLGVATIDGREFVLADIPGLIEGAHEGVGIGDRFLGHVERTRVL
LHLVSAQEEKVGKAYKTVKAELDAYGGGLTDKPEIVALSQIDVLDEKELKKKAKELEKACGRPPLLLSAAAHIGMTEALR
ALRDIIVSASNGGDTALPDRSMPHESEVEEEDDRL
>Mature_355_residues
MKFLDEAKVYIKSGDGGAGAVSFRREKFIEFGGPDGGDGGRGGDVWVEVVNGLNTLIDFRFQQHFKASIGQHGMGKTRTG
AKGSDVVLKVPVGTQIFEEDNETLIMDLTKEGQRFRLAAGGNGGFGNAYFKSSTNQAPTHANPGLAGEEKTIWLRLKLIA
DAGLVGLPNAGKSTFLATVTRARPKIANYPFTTLHPNLGVATIDGREFVLADIPGLIEGAHEGVGIGDRFLGHVERTRVL
LHLVSAQEEKVGKAYKTVKAELDAYGGGLTDKPEIVALSQIDVLDEKELKKKAKELEKACGRPPLLLSAAAHIGMTEALR
ALRDIIVSASNGGDTALPDRSMPHESEVEEEDDRL

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=311, Percent_Identity=37.9421221864952, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI111955139, Length=298, Percent_Identity=37.9194630872483, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI111955063, Length=132, Percent_Identity=40.9090909090909, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI58761500, Length=104, Percent_Identity=34.6153846153846, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789574, Length=334, Percent_Identity=48.2035928143713, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1787454, Length=106, Percent_Identity=38.6792452830189, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=324, Percent_Identity=37.962962962963, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=309, Percent_Identity=30.0970873786408, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17509631, Length=102, Percent_Identity=39.2156862745098, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=124, Percent_Identity=33.8709677419355, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=113, Percent_Identity=45.1327433628319, Blast_Score=99, Evalue=8e-22,
Organism=Drosophila melanogaster, GI20129375, Length=326, Percent_Identity=36.5030674846626, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24585318, Length=305, Percent_Identity=34.7540983606557, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24640873, Length=157, Percent_Identity=30.5732484076433, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640877, Length=157, Percent_Identity=30.5732484076433, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640875, Length=157, Percent_Identity=30.5732484076433, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356473, Length=117, Percent_Identity=35.8974358974359, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_AGRT5 (Q7CW97)

Other databases:

- EMBL:   AE007869
- RefSeq:   NP_355711.2
- HSSP:   P20964
- ProteinModelPortal:   Q7CW97
- SMR:   Q7CW97
- STRING:   Q7CW97
- GeneID:   1134819
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2781
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- ProtClustDB:   PRK12299
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 38026; Mature: 38026

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDEAKVYIKSGDGGAGAVSFRREKFIEFGGPDGGDGGRGGDVWVEVVNGLNTLIDFR
CCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FQQHFKASIGQHGMGKTRTGAKGSDVVLKVPVGTQIFEEDNETLIMDLTKEGQRFRLAAG
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCEEEEEECCCCCEEEEEEC
GNGGFGNAYFKSSTNQAPTHANPGLAGEEKTIWLRLKLIADAGLVGLPNAGKSTFLATVT
CCCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCEEECCCCCCCHHEEHHH
RARPKIANYPFTTLHPNLGVATIDGREFVLADIPGLIEGAHEGVGIGDRFLGHVERTRVL
HCCCCCCCCCCEEECCCCCEEEECCCEEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHH
LHLVSAQEEKVGKAYKTVKAELDAYGGGLTDKPEIVALSQIDVLDEKELKKKAKELEKAC
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
GRPPLLLSAAAHIGMTEALRALRDIIVSASNGGDTALPDRSMPHESEVEEEDDRL
CCCCEEHHHHHHCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MKFLDEAKVYIKSGDGGAGAVSFRREKFIEFGGPDGGDGGRGGDVWVEVVNGLNTLIDFR
CCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FQQHFKASIGQHGMGKTRTGAKGSDVVLKVPVGTQIFEEDNETLIMDLTKEGQRFRLAAG
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCEEEEEECCCCCEEEEEEC
GNGGFGNAYFKSSTNQAPTHANPGLAGEEKTIWLRLKLIADAGLVGLPNAGKSTFLATVT
CCCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCEEECCCCCCCHHEEHHH
RARPKIANYPFTTLHPNLGVATIDGREFVLADIPGLIEGAHEGVGIGDRFLGHVERTRVL
HCCCCCCCCCCEEECCCCCEEEECCCEEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHH
LHLVSAQEEKVGKAYKTVKAELDAYGGGLTDKPEIVALSQIDVLDEKELKKKAKELEKAC
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
GRPPLLLSAAAHIGMTEALRALRDIIVSASNGGDTALPDRSMPHESEVEEEDDRL
CCCCEEHHHHHHCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743194; 11743193