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The map label for this gene is nodT [H]

Identifier: 159185264

GI number: 159185264

Start: 2525519

End: 2526973

Strand: Direct

Name: nodT [H]

Synonym: Atu2552

Alternate gene names: 159185264

Gene position: 2525519-2526973 (Clockwise)

Preceding gene: 15889810

Following gene: 15889813

Centisome position: 88.88

GC content: 60.34

Gene sequence:

>1455_bases
ATGCTGTCTATTCGCGCCACTCTTCCCCTGACAATGCTGCTGCTTTCAGGCTGTGTTGTCGGGCCAGACCACCAGACGCC
GGAAATTCAATTGCCGGGCAAGTTTGCGGAAGCCGGAAAAACCAGTAATGGCGACATCAGCACCGTGGCATGGTGGAATG
CATTCAACGACAGCCGCCTCAATGGTTACGTTTCCACCGGCCTCACGCAGAACCTGACGGTTCTGCAGGCGATCGAGCGC
ATCAATCAGGCTCAATCCAACATTACCGTGGCTGGCGCGGGCTCTCTACCGAGCCTGACCTCCACATTCCGTCACCAGAC
CCAGGGCAGCGGCGGAAGCCTGCCTTCCACGAACGATAACGTCACCAACACGACGAGCAATGCTTTCAACGTCGGCTGGT
TGCTGGACCTGTTCGGCCAATACCGTCGCGCTCAGGAAAGCGCGGGCGCATCGCTCGATGCCGCCTATGCAACGGCCAAC
GTTCAGCGCCTGACCTTGATCTCCGCTGTTACGTCCGCCTACATCGACGTGCGCTATTATCAGGAGCGTCTGGCGATCGC
CCGTCAGAACCTCGGTTCTCGTCGCGAGACACTCAGCCTGACGAAGTTGCAGCTGGACGCCGGTGCGGCTTCCCGCCTGG
ACGTCGTTCAGTCCGAAGGTCTCGTGAATTCCACGCTTGCTCAAATGCCGGCGCTGGAAACGAATTTCCGTCGCGCAGCA
CACCGCATCGCGACCCTGCTCGGCATGCCAGCCGACTCGCTTGTGATGGAGCTTCAAAGAGGCGCGCGCCAGCCTGTTGC
CCGCACCATTCCGCGTACTGGTATTCCGGCCGACCTTATTCGCAACAGACCGGATATCCGCGTTGCTGAACGCCAGCTCG
CGGCTGCGGTGGCGGATATTGGCGTTGCAGAGGCGCAGCTCTATCCAAGCATCACGCTGAGCGGTTCGATTACACCGAGC
TTCACCAAAATCAGCAATGGTGCGAGCGGCACGTCCAATGGCTGGGGCTTTGGCCCTTCGATCACGCTGCCGATCCTTGA
TGGCGGAAGACTGCGCGCTGGCGTTGACATCCAGAAGTCCGTTGCCCGTGAACAGTACCTTGCCTGGAAGGCGACCGTTC
TGAATGCGGTGGAAGAAGTCGAAAACGCCCTGACTGCGCTTAATCGCGATCAGCAGACGGTCAGTGCGTATCGCAGAACC
GTTTCCTCCTATCAGGAGGCGCTCTCGCTGGCGACCGCCAGCTATCGCGATGGCGCGTCCTCGCTCCTTGATGTTCTCGA
CGCCCAGCGTAACGTCTCCGACGCCCAGTCACAGCTTGCAACGGCCATCCAGCAGGCGGCGCAGGATTACGTAGCATTGA
GCGTTGCACTCGGCGGCGGTTACGCCGTTGGCCAGACGGCCACATCGAAGGGTGGTCCGACGATCGCCGCTGCTGTTGCT
GCCAAGCGTATGTAA

Upstream 100 bases:

>100_bases
GCCGATTTGGCTAATGCACGTTTCTAGGGCATATCGACCGCGCAGCCCATTTTTCAGCAAGCCGCGCTCGGTAAGCCAAC
CTAAGAATTGGGAAAATTAC

Downstream 100 bases:

>100_bases
CCAGCGCCAAAAAAGACAAACAAAGAGCCCGCGTTTCGACGCGGGCTTTTTGTTATTTCACGTCACAAAATAAAAAAAGC
ACCGGTCGCCCGGTGCTTTG

Product: nodulation protein T precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MLSIRATLPLTMLLLSGCVVGPDHQTPEIQLPGKFAEAGKTSNGDISTVAWWNAFNDSRLNGYVSTGLTQNLTVLQAIER
INQAQSNITVAGAGSLPSLTSTFRHQTQGSGGSLPSTNDNVTNTTSNAFNVGWLLDLFGQYRRAQESAGASLDAAYATAN
VQRLTLISAVTSAYIDVRYYQERLAIARQNLGSRRETLSLTKLQLDAGAASRLDVVQSEGLVNSTLAQMPALETNFRRAA
HRIATLLGMPADSLVMELQRGARQPVARTIPRTGIPADLIRNRPDIRVAERQLAAAVADIGVAEAQLYPSITLSGSITPS
FTKISNGASGTSNGWGFGPSITLPILDGGRLRAGVDIQKSVAREQYLAWKATVLNAVEEVENALTALNRDQQTVSAYRRT
VSSYQEALSLATASYRDGASSLLDVLDAQRNVSDAQSQLATAIQQAAQDYVALSVALGGGYAVGQTATSKGGPTIAAAVA
AKRM

Sequences:

>Translated_484_residues
MLSIRATLPLTMLLLSGCVVGPDHQTPEIQLPGKFAEAGKTSNGDISTVAWWNAFNDSRLNGYVSTGLTQNLTVLQAIER
INQAQSNITVAGAGSLPSLTSTFRHQTQGSGGSLPSTNDNVTNTTSNAFNVGWLLDLFGQYRRAQESAGASLDAAYATAN
VQRLTLISAVTSAYIDVRYYQERLAIARQNLGSRRETLSLTKLQLDAGAASRLDVVQSEGLVNSTLAQMPALETNFRRAA
HRIATLLGMPADSLVMELQRGARQPVARTIPRTGIPADLIRNRPDIRVAERQLAAAVADIGVAEAQLYPSITLSGSITPS
FTKISNGASGTSNGWGFGPSITLPILDGGRLRAGVDIQKSVAREQYLAWKATVLNAVEEVENALTALNRDQQTVSAYRRT
VSSYQEALSLATASYRDGASSLLDVLDAQRNVSDAQSQLATAIQQAAQDYVALSVALGGGYAVGQTATSKGGPTIAAAVA
AKRM
>Mature_484_residues
MLSIRATLPLTMLLLSGCVVGPDHQTPEIQLPGKFAEAGKTSNGDISTVAWWNAFNDSRLNGYVSTGLTQNLTVLQAIER
INQAQSNITVAGAGSLPSLTSTFRHQTQGSGGSLPSTNDNVTNTTSNAFNVGWLLDLFGQYRRAQESAGASLDAAYATAN
VQRLTLISAVTSAYIDVRYYQERLAIARQNLGSRRETLSLTKLQLDAGAASRLDVVQSEGLVNSTLAQMPALETNFRRAA
HRIATLLGMPADSLVMELQRGARQPVARTIPRTGIPADLIRNRPDIRVAERQLAAAVADIGVAEAQLYPSITLSGSITPS
FTKISNGASGTSNGWGFGPSITLPILDGGRLRAGVDIQKSVAREQYLAWKATVLNAVEEVENALTALNRDQQTVSAYRRT
VSSYQEALSLATASYRDGASSLLDVLDAQRNVSDAQSQLATAIQQAAQDYVALSVALGGGYAVGQTATSKGGPTIAAAVA
AKRM

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=465, Percent_Identity=28.3870967741935, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI2367348, Length=479, Percent_Identity=23.7995824634656, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 51237; Mature: 51237

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIRATLPLTMLLLSGCVVGPDHQTPEIQLPGKFAEAGKTSNGDISTVAWWNAFNDSRL
CCEECHHHHHHHHHHCCCEECCCCCCCCEECCCCHHHCCCCCCCCEEEEEEECCCCCCCC
NGYVSTGLTQNLTVLQAIERINQAQSNITVAGAGSLPSLTSTFRHQTQGSGGSLPSTNDN
CCEECCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCC
VTNTTSNAFNVGWLLDLFGQYRRAQESAGASLDAAYATANVQRLTLISAVTSAYIDVRYY
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QERLAIARQNLGSRRETLSLTKLQLDAGAASRLDVVQSEGLVNSTLAQMPALETNFRRAA
HHHHHHHHHHCCCHHHHHHHHEEEECCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
HRIATLLGMPADSLVMELQRGARQPVARTIPRTGIPADLIRNRPDIRVAERQLAAAVADI
HHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHC
GVAEAQLYPSITLSGSITPSFTKISNGASGTSNGWGFGPSITLPILDGGRLRAGVDIQKS
CHHHHHHCCCEEECCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCCHHHH
VAREQYLAWKATVLNAVEEVENALTALNRDQQTVSAYRRTVSSYQEALSLATASYRDGAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SLLDVLDAQRNVSDAQSQLATAIQQAAQDYVALSVALGGGYAVGQTATSKGGPTIAAAVA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEECCCCCCCCCCHHHHHHH
AKRM
HHCC
>Mature Secondary Structure
MLSIRATLPLTMLLLSGCVVGPDHQTPEIQLPGKFAEAGKTSNGDISTVAWWNAFNDSRL
CCEECHHHHHHHHHHCCCEECCCCCCCCEECCCCHHHCCCCCCCCEEEEEEECCCCCCCC
NGYVSTGLTQNLTVLQAIERINQAQSNITVAGAGSLPSLTSTFRHQTQGSGGSLPSTNDN
CCEECCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCC
VTNTTSNAFNVGWLLDLFGQYRRAQESAGASLDAAYATANVQRLTLISAVTSAYIDVRYY
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QERLAIARQNLGSRRETLSLTKLQLDAGAASRLDVVQSEGLVNSTLAQMPALETNFRRAA
HHHHHHHHHHCCCHHHHHHHHEEEECCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
HRIATLLGMPADSLVMELQRGARQPVARTIPRTGIPADLIRNRPDIRVAERQLAAAVADI
HHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHC
GVAEAQLYPSITLSGSITPSFTKISNGASGTSNGWGFGPSITLPILDGGRLRAGVDIQKS
CHHHHHHCCCEEECCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCCHHHH
VAREQYLAWKATVLNAVEEVENALTALNRDQQTVSAYRRTVSSYQEALSLATASYRDGAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SLLDVLDAQRNVSDAQSQLATAIQQAAQDYVALSVALGGGYAVGQTATSKGGPTIAAAVA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEECCCCCCCCCCHHHHHHH
AKRM
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2303029; 2338917 [H]