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The map label for this gene is asd [H]

Identifier: 159185239

GI number: 159185239

Start: 2458979

End: 2460013

Strand: Reverse

Name: asd [H]

Synonym: Atu2490

Alternate gene names: 159185239

Gene position: 2460013-2458979 (Counterclockwise)

Preceding gene: 159185240

Following gene: 159185238

Centisome position: 86.57

GC content: 57.2

Gene sequence:

>1035_bases
ATGGGTTTCAAAGTTGCAATTGTAGGCGCTACCGGCAATGTCGGTCGCGAAATGCTCAACATCCTGGCCGAACGTGGTTT
TCCGGCAGATGAAGTCGTGCCGCTCGCTTCCTCCCGCTCGCAGGGCACGGAAGTCTCCTATGGCGATCGCACGCTGAAGG
TTTCCAACCTCGAAAACTACGATTTTTCCGACACGGATATTTGCCTGATGTCGGCCGGCGGCGAGATTTCCAAGAAGTGG
TCGCCGAAGATCGGTCAGCAGGGTTGCGTCGTCATCGATAACTCGTCTGCATGGCGCTATGATCAGGATGTTCCGCTGAT
CGTTCCGGAAGTCAATGCCGATGCGATCTCGGGCTTCACGCGCAAGAACATCATTGCCAACCCCAATTGCTCCACGGCCC
AGCTCGTTGTCGCGCTGAAGCCGCTGCATGATTTCGCCAAGATCAAGCGCGTCGTTGTGTCCACCTATCAGTCGGTTTCC
GGCGCCGGCAAGGAAGGCATGGACGAGCTGTTCCAGCAGACCCGCGCCGTCTTCGTGGCCGATCCGGTCGAAACCAAGAA
GTTCACCAAGCGCATCGCCTTCAACGTCATCCCGCATATCGACGTCTTCATGGAAGACGGCTACACCAAGGAAGAGTGGA
AGGTTCTGGCCGAAACCAAGAAGATGCTTGATCCCAAGATCAAGGTCACCTGCACGGCCGTGCGCGTTCCGGTCTTCATC
GGCCATTCGGAATCGGTCAATATCGAGTTCGAAAACGAGATCACTGCCGATCAGGCGCGTGACATCCTGCGCGAAGCGCC
GGGTTGCCTCGTCATCGACAAGCATGAAGATGGCGGCTACATCACCCCCGTTGAATCCGCCGGTGAAGATGCGACCTATA
TTTCGCGTATCCGCGAGGATGCGACGGTCGAGAACGGCCTCAACATCTGGGTTGTTTCGGATAATCTGCGCAAGGGCGCT
GCCCTCAATGCCATCCAGATCGCCGAACTGCTGGTCAATCGTGGTCTCATCAAGCCCCGCAAGGCGGCTGCCTGA

Upstream 100 bases:

>100_bases
ACCGCTCTCTCCCCGGTTTGGCTGGGGATCGAGGAAGCCGCAATGCGATGCGGGTTCCCCACCTCACCCAAAAGAGGAGA
GACAGAAAGAGAGCTTGATC

Downstream 100 bases:

>100_bases
TACGATTTTTTAAGGTTCGTTAAGTATAACCCGTCTGTTCTGTGTGGGGCAGGCGGGTTTTTCAATTGGCTGTCATCACG
GCCAGTTTATTTGCAGGCCT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGFKVAIVGATGNVGREMLNILAERGFPADEVVPLASSRSQGTEVSYGDRTLKVSNLENYDFSDTDICLMSAGGEISKKW
SPKIGQQGCVVIDNSSAWRYDQDVPLIVPEVNADAISGFTRKNIIANPNCSTAQLVVALKPLHDFAKIKRVVVSTYQSVS
GAGKEGMDELFQQTRAVFVADPVETKKFTKRIAFNVIPHIDVFMEDGYTKEEWKVLAETKKMLDPKIKVTCTAVRVPVFI
GHSESVNIEFENEITADQARDILREAPGCLVIDKHEDGGYITPVESAGEDATYISRIREDATVENGLNIWVVSDNLRKGA
ALNAIQIAELLVNRGLIKPRKAAA

Sequences:

>Translated_344_residues
MGFKVAIVGATGNVGREMLNILAERGFPADEVVPLASSRSQGTEVSYGDRTLKVSNLENYDFSDTDICLMSAGGEISKKW
SPKIGQQGCVVIDNSSAWRYDQDVPLIVPEVNADAISGFTRKNIIANPNCSTAQLVVALKPLHDFAKIKRVVVSTYQSVS
GAGKEGMDELFQQTRAVFVADPVETKKFTKRIAFNVIPHIDVFMEDGYTKEEWKVLAETKKMLDPKIKVTCTAVRVPVFI
GHSESVNIEFENEITADQARDILREAPGCLVIDKHEDGGYITPVESAGEDATYISRIREDATVENGLNIWVVSDNLRKGA
ALNAIQIAELLVNRGLIKPRKAAA
>Mature_343_residues
GFKVAIVGATGNVGREMLNILAERGFPADEVVPLASSRSQGTEVSYGDRTLKVSNLENYDFSDTDICLMSAGGEISKKWS
PKIGQQGCVVIDNSSAWRYDQDVPLIVPEVNADAISGFTRKNIIANPNCSTAQLVVALKPLHDFAKIKRVVVSTYQSVSG
AGKEGMDELFQQTRAVFVADPVETKKFTKRIAFNVIPHIDVFMEDGYTKEEWKVLAETKKMLDPKIKVTCTAVRVPVFIG
HSESVNIEFENEITADQARDILREAPGCLVIDKHEDGGYITPVESAGEDATYISRIREDATVENGLNIWVVSDNLRKGAA
LNAIQIAELLVNRGLIKPRKAAA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=338, Percent_Identity=33.4319526627219, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1789841, Length=353, Percent_Identity=26.3456090651558, Blast_Score=95, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=398, Percent_Identity=29.8994974874372, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37660; Mature: 37529

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKVAIVGATGNVGREMLNILAERGFPADEVVPLASSRSQGTEVSYGDRTLKVSNLENY
CCEEEEEEECCCHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCEEECCCEEEEECCCCCC
DFSDTDICLMSAGGEISKKWSPKIGQQGCVVIDNSSAWRYDQDVPLIVPEVNADAISGFT
CCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCHHHCCCH
RKNIIANPNCSTAQLVVALKPLHDFAKIKRVVVSTYQSVSGAGKEGMDELFQQTRAVFVA
HCCEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEE
DPVETKKFTKRIAFNVIPHIDVFMEDGYTKEEWKVLAETKKMLDPKIKVTCTAVRVPVFI
CCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEE
GHSESVNIEFENEITADQARDILREAPGCLVIDKHEDGGYITPVESAGEDATYISRIRED
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCCCHHHHHHHHHH
ATVENGLNIWVVSDNLRKGAALNAIQIAELLVNRGLIKPRKAAA
HHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHCCC
>Mature Secondary Structure 
GFKVAIVGATGNVGREMLNILAERGFPADEVVPLASSRSQGTEVSYGDRTLKVSNLENY
CEEEEEEECCCHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCEEECCCEEEEECCCCCC
DFSDTDICLMSAGGEISKKWSPKIGQQGCVVIDNSSAWRYDQDVPLIVPEVNADAISGFT
CCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCHHHCCCH
RKNIIANPNCSTAQLVVALKPLHDFAKIKRVVVSTYQSVSGAGKEGMDELFQQTRAVFVA
HCCEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEE
DPVETKKFTKRIAFNVIPHIDVFMEDGYTKEEWKVLAETKKMLDPKIKVTCTAVRVPVFI
CCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEE
GHSESVNIEFENEITADQARDILREAPGCLVIDKHEDGGYITPVESAGEDATYISRIRED
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCCCHHHHHHHHHH
ATVENGLNIWVVSDNLRKGAALNAIQIAELLVNRGLIKPRKAAA
HHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]