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The map label for this gene is betI [H]

Identifier: 159185031

GI number: 159185031

Start: 2023333

End: 2023926

Strand: Reverse

Name: betI [H]

Synonym: Atu2059

Alternate gene names: 159185031

Gene position: 2023926-2023333 (Counterclockwise)

Preceding gene: 15889350

Following gene: 15889341

Centisome position: 71.23

GC content: 58.42

Gene sequence:

>594_bases
ATGCGACTCACTAAAATAAGCGATATTCGTCGGGCCGAGCTGAGACGTGCAGCATTCGAAGTGTTGCAGAGAGAGGGCAT
GGCCGGGGCAACGCTCGAAAGGGTGGCTGCACAGGCGGGCGCCTCCAAAGGCATCGTGCTGCATTATTTTGCAAGCAAGC
AGGAACTGTTCGAACATGCGATGCGTGAAGCCAATGTGAAACTGGCGGAGGTCGTTGTGGCGAGGCTTAATCGCGCCACA
AGCCCGCGGGAGAGACTGGAGGCAATTATCGAGGCCAACTTCGACGAGAGCTTCTTTCAGCCATCGATCTGTCATGCCTG
GCTTTCGCTATGCGCGGAGGTTCCGCGTGAGCCGCAGCTTGGGCGAATTCAGAAGGTCATCCATGCGCGCATGCGCTCCA
ATCTGCTCTCTGCCTTGCGGCATCTCGTGCCGAAAGGGGACTGTGAACCCATTGCACTGGGCATTACCACATTGATCGAC
GGGCTATGGCTGCGGTCGGGGCTGCAATCGGGAGGTCTGTCGAGGGAAGAGGCGTTGGCGCAAATGCGCGACTACCTGTT
ACACCGATTGCCAAGTCCGGAGGCCGCCGCTTGA

Upstream 100 bases:

>100_bases
ATGAGGCAGCCTTTTGTCTTAGTGGTTACTAAATTGACCAATGGGACAATAATTGATCTTTTGGGGAAATTTGTCAATGT
GTCTCTGCAAGGAGACTGAA

Downstream 100 bases:

>100_bases
TGGCTTGGGCCAGTGACGACGAGGGCTGAACCATGGAACCAGGTTCTTCCTGCCGCATTATTCCACCATGAAGAAAACGA
CCCGCAAACCATTGAACAGG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MRLTKISDIRRAELRRAAFEVLQREGMAGATLERVAAQAGASKGIVLHYFASKQELFEHAMREANVKLAEVVVARLNRAT
SPRERLEAIIEANFDESFFQPSICHAWLSLCAEVPREPQLGRIQKVIHARMRSNLLSALRHLVPKGDCEPIALGITTLID
GLWLRSGLQSGGLSREEALAQMRDYLLHRLPSPEAAA

Sequences:

>Translated_197_residues
MRLTKISDIRRAELRRAAFEVLQREGMAGATLERVAAQAGASKGIVLHYFASKQELFEHAMREANVKLAEVVVARLNRAT
SPRERLEAIIEANFDESFFQPSICHAWLSLCAEVPREPQLGRIQKVIHARMRSNLLSALRHLVPKGDCEPIALGITTLID
GLWLRSGLQSGGLSREEALAQMRDYLLHRLPSPEAAA
>Mature_197_residues
MRLTKISDIRRAELRRAAFEVLQREGMAGATLERVAAQAGASKGIVLHYFASKQELFEHAMREANVKLAEVVVARLNRAT
SPRERLEAIIEANFDESFFQPSICHAWLSLCAEVPREPQLGRIQKVIHARMRSNLLSALRHLVPKGDCEPIALGITTLID
GLWLRSGLQSGGLSREEALAQMRDYLLHRLPSPEAAA

Specific function: Repressor involved in choline regulation of the bet genes [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786505, Length=189, Percent_Identity=35.978835978836, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR017757
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21958; Mature: 21958

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTKISDIRRAELRRAAFEVLQREGMAGATLERVAAQAGASKGIVLHYFASKQELFEHA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
MREANVKLAEVVVARLNRATSPRERLEAIIEANFDESFFQPSICHAWLSLCAEVPREPQL
HHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCH
GRIQKVIHARMRSNLLSALRHLVPKGDCEPIALGITTLIDGLWLRSGLQSGGLSREEALA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QMRDYLLHRLPSPEAAA
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRLTKISDIRRAELRRAAFEVLQREGMAGATLERVAAQAGASKGIVLHYFASKQELFEHA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
MREANVKLAEVVVARLNRATSPRERLEAIIEANFDESFFQPSICHAWLSLCAEVPREPQL
HHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCH
GRIQKVIHARMRSNLLSALRHLVPKGDCEPIALGITTLIDGLWLRSGLQSGGLSREEALA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QMRDYLLHRLPSPEAAA
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA