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The map label for this gene is macB [H]

Identifier: 159184931

GI number: 159184931

Start: 1797055

End: 1798263

Strand: Direct

Name: macB [H]

Synonym: Atu1817

Alternate gene names: 159184931

Gene position: 1797055-1798263 (Clockwise)

Preceding gene: 15889119

Following gene: 159184932

Centisome position: 63.24

GC content: 61.95

Gene sequence:

>1209_bases
ATGTTCTTTGAAACGTCACGTCTTGCGCTGCGCGCCATCAGCCGCAACCTTTTGCGCTCTTTCCTCACAGTGCTTGGCGT
CGTCATTGGTGTGGCCGCCGTCATCGCCATGGTCACCATCGGCAATGGCACGACGGAACAGGTGAAATCGGAACTGTCGC
GGCTCGGTACCAACATGCTGTTCGTGCGCCCCGGTCAGTTCGGCCCCGGCCGCGCCAGCACCGAGGCGAAACGTTTCGAT
GACCGCGATGTCGAGGCCATCCGCAACCAGATATCAGGCATCCGCGCCGTCGCGCCACAGAACCGCAGTTCCGCGGCCAC
TGTCATTTTCGGCGGCAAGAACCACCAGACGAGCGTCATCGGCACCACCAACGATTACCTGATCGCCCAGGACTGGACCA
TCGCGCTCGGCCGCGACTTCCAGCCCGCCGAAGATCGTGGCGGCCAGATCGGCTGCATCATCGGTGAAACGGTGCGCCAA
GAACTGTTTGGCGCGGAAAACCCTGTGGGTCAGACCATTCGCGTCAGCAATATCTCCTGCCCCGTCATCGGTGTCCTCGC
CAGAAAAGGCCAGTCCGGCCTCGGGGACGATCAGGACGACACCATCATCATGCCGCTCAAAATCCACCAGCGGCGCATCG
GCGGCACCACCACCATCTCCTCGATCATGGTCTCGGCACAGGACGGCGTTTCCACCGCCAAGGTGCAGAGCGACCTGCAG
AACCTGCTGCGTGAGCGGCGGCGCATCAACATTGGCCGCGAGGATGATTTCACCGTCAACGACATGACACAGATCGCCTC
TGCCATGACCGGCACGACGACACTGCTCACCGGGCTTTTGGGTGCGGTCGCCGCCGTCAGCCTTCTTGTCGGCGGCATCG
GCATCATGAACATCATGCTGGTGTCGGTGACAGAACGCACCCGCGAAATCGGCATTCGCCTTGCCATCGGCGCGCTGGAA
AAACAGGTGCTGACGCAGTTTCTGGTGGAAGCCGTCATGCTGTCGGCCTTCGGCGGCATCGTCGGCATTCTGACGGGTCT
CGGCCTCGCCTATAGCGTCGTCAGCTTCCTCAACGTGCCTTTCGTCACCAGCCCGTCGATCATCTTCCTCGCCTTCGCCT
TTTCAGCGGCCATCGGGGTGATTTTCGGCTATTTTCCGGCGCGGCGGGCAGCGAGTTTGAGCCCGATCGAGGCGCTGCGG
CATGAGTGA

Upstream 100 bases:

>100_bases
ACCCATGAAGAGGATATTGCTGCCCACGCCGGACGCCTGTTGCGCTTTGTCGATGGCCACCTCGCCTCCGACAGCGCGGC
CGACGAAAAGGAGACATCCG

Downstream 100 bases:

>100_bases
GGAAAGCCGTCGAGGCTGCAACGGCTTCGAGCGAATAGGTTCACAAATTGCCGGAAGGGGTTTCTATGTTCAAATCGGTA
TCGGACAGCGCGGCTGCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MFFETSRLALRAISRNLLRSFLTVLGVVIGVAAVIAMVTIGNGTTEQVKSELSRLGTNMLFVRPGQFGPGRASTEAKRFD
DRDVEAIRNQISGIRAVAPQNRSSAATVIFGGKNHQTSVIGTTNDYLIAQDWTIALGRDFQPAEDRGGQIGCIIGETVRQ
ELFGAENPVGQTIRVSNISCPVIGVLARKGQSGLGDDQDDTIIMPLKIHQRRIGGTTTISSIMVSAQDGVSTAKVQSDLQ
NLLRERRRINIGREDDFTVNDMTQIASAMTGTTTLLTGLLGAVAAVSLLVGGIGIMNIMLVSVTERTREIGIRLAIGALE
KQVLTQFLVEAVMLSAFGGIVGILTGLGLAYSVVSFLNVPFVTSPSIIFLAFAFSAAIGVIFGYFPARRAASLSPIEALR
HE

Sequences:

>Translated_402_residues
MFFETSRLALRAISRNLLRSFLTVLGVVIGVAAVIAMVTIGNGTTEQVKSELSRLGTNMLFVRPGQFGPGRASTEAKRFD
DRDVEAIRNQISGIRAVAPQNRSSAATVIFGGKNHQTSVIGTTNDYLIAQDWTIALGRDFQPAEDRGGQIGCIIGETVRQ
ELFGAENPVGQTIRVSNISCPVIGVLARKGQSGLGDDQDDTIIMPLKIHQRRIGGTTTISSIMVSAQDGVSTAKVQSDLQ
NLLRERRRINIGREDDFTVNDMTQIASAMTGTTTLLTGLLGAVAAVSLLVGGIGIMNIMLVSVTERTREIGIRLAIGALE
KQVLTQFLVEAVMLSAFGGIVGILTGLGLAYSVVSFLNVPFVTSPSIIFLAFAFSAAIGVIFGYFPARRAASLSPIEALR
HE
>Mature_402_residues
MFFETSRLALRAISRNLLRSFLTVLGVVIGVAAVIAMVTIGNGTTEQVKSELSRLGTNMLFVRPGQFGPGRASTEAKRFD
DRDVEAIRNQISGIRAVAPQNRSSAATVIFGGKNHQTSVIGTTNDYLIAQDWTIALGRDFQPAEDRGGQIGCIIGETVRQ
ELFGAENPVGQTIRVSNISCPVIGVLARKGQSGLGDDQDDTIIMPLKIHQRRIGGTTTISSIMVSAQDGVSTAKVQSDLQ
NLLRERRRINIGREDDFTVNDMTQIASAMTGTTTLLTGLLGAVAAVSLLVGGIGIMNIMLVSVTERTREIGIRLAIGALE
KQVLTQFLVEAVMLSAFGGIVGILTGLGLAYSVVSFLNVPFVTSPSIIFLAFAFSAAIGVIFGYFPARRAASLSPIEALR
HE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=410, Percent_Identity=36.0975609756098, Blast_Score=200, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42895; Mature: 42895

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFETSRLALRAISRNLLRSFLTVLGVVIGVAAVIAMVTIGNGTTEQVKSELSRLGTNML
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEE
FVRPGQFGPGRASTEAKRFDDRDVEAIRNQISGIRAVAPQNRSSAATVIFGGKNHQTSVI
EEECCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCCEEEE
GTTNDYLIAQDWTIALGRDFQPAEDRGGQIGCIIGETVRQELFGAENPVGQTIRVSNISC
ECCCCEEEECCEEEEECCCCCCHHHCCCEEEEEEHHHHHHHHCCCCCCCCCEEEECCCCC
PVIGVLARKGQSGLGDDQDDTIIMPLKIHQRRIGGTTTISSIMVSAQDGVSTAKVQSDLQ
HHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHH
NLLRERRRINIGREDDFTVNDMTQIASAMTGTTTLLTGLLGAVAAVSLLVGGIGIMNIML
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVTERTREIGIRLAIGALEKQVLTQFLVEAVMLSAFGGIVGILTGLGLAYSVVSFLNVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FVTSPSIIFLAFAFSAAIGVIFGYFPARRAASLSPIEALRHE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
>Mature Secondary Structure
MFFETSRLALRAISRNLLRSFLTVLGVVIGVAAVIAMVTIGNGTTEQVKSELSRLGTNML
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEE
FVRPGQFGPGRASTEAKRFDDRDVEAIRNQISGIRAVAPQNRSSAATVIFGGKNHQTSVI
EEECCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCCEEEE
GTTNDYLIAQDWTIALGRDFQPAEDRGGQIGCIIGETVRQELFGAENPVGQTIRVSNISC
ECCCCEEEECCEEEEECCCCCCHHHCCCEEEEEEHHHHHHHHCCCCCCCCCEEEECCCCC
PVIGVLARKGQSGLGDDQDDTIIMPLKIHQRRIGGTTTISSIMVSAQDGVSTAKVQSDLQ
HHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHH
NLLRERRRINIGREDDFTVNDMTQIASAMTGTTTLLTGLLGAVAAVSLLVGGIGIMNIML
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVTERTREIGIRLAIGALEKQVLTQFLVEAVMLSAFGGIVGILTGLGLAYSVVSFLNVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FVTSPSIIFLAFAFSAAIGVIFGYFPARRAASLSPIEALRHE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA