Click here to switch to the map view.

The map label for this gene is ytxM [H]

Identifier: 159184821

GI number: 159184821

Start: 1558406

End: 1559182

Strand: Reverse

Name: ytxM [H]

Synonym: Atu1572

Alternate gene names: 159184821

Gene position: 1559182-1558406 (Counterclockwise)

Preceding gene: 15888893

Following gene: 159184820

Centisome position: 54.87

GC content: 62.55

Gene sequence:

>777_bases
ATGAATCTCAACCTGCCGCAATTTTCCGATTTTTCCCATGACGGCCTTCGCCTTGCCTATTTCGATGAGGGCGATCCGGC
GGGTGATCCGGTTCTACTGATCCACGGCTTCGCCTCCAGCGCCAATGTCAACTGGGTGCATCCCGGCTGGGTGAAGACGC
TGGGAGAGGCGGGCTACCGGGTGATTGCCATCGACAATCGCGGCCATGGTGCAAGTGACAAGCCACATGATTCCGAGGCC
TATTACCCGTCGGTCATGGCAGGGGATGCCGTGGCGCTGCTCAATCATCTCGGCATCGCGGAAACGCATGTGATGGGCTA
TTCCATGGGTGCGCGGATTTCCGCCTTTCTGGCCATGGCTCATCCGGAACGTGTGCGTTCGCTGGTGTTCGGCGGGCTCG
GCATCGGCATGGTGGAAGGTGTGGGCGACTGGGATCCGATCGCGGAGGCGCTGCTTGCCCCTTCGCTCGATGTGGTCACC
CATGAGCGCGGCCGCATGTTCCGCGCCTTTGCGGACCAGACCAAAAGTGACCGGCTGGCGCTTGCCGCCTGCATCGAGAC
ATCGCGGGTTCTCGTCACGCGCGAACAGGCACAAAAGATCGATGCCCCGACGCTGATCGCGGTTGGAACGAAGGACGACA
TCGCCGGATCGGGTGCGGAGCTGGCCGCGATCATGCCGCATGCGCGGGCGATCGACATCCCCGGCCGCGACCATATGCTG
GCCGTTGGCGACCGGGTGTTCAAGGCGGCGGTGCTGGAGTTTTACCGCTCGCTTTGA

Upstream 100 bases:

>100_bases
ATGTAGCCTCAAACGCATTGCATCTCCATAAAAATCGTCAGCAAAACATGTTCAATCTTGCGCTTTCCTGCCATATGGTC
CGGCAAAAAGGATGTCCTTG

Downstream 100 bases:

>100_bases
TGTGGGGCATGTCCAGCAAAACCGGAGCCCGGTTTTCCGTCCACAAATGCGGCAACGCGGAGGATGGCAAGAAACGGTTT
TTTATGCTGCATGAAGAAAA

Product: hydrolase

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MNLNLPQFSDFSHDGLRLAYFDEGDPAGDPVLLIHGFASSANVNWVHPGWVKTLGEAGYRVIAIDNRGHGASDKPHDSEA
YYPSVMAGDAVALLNHLGIAETHVMGYSMGARISAFLAMAHPERVRSLVFGGLGIGMVEGVGDWDPIAEALLAPSLDVVT
HERGRMFRAFADQTKSDRLALAACIETSRVLVTREQAQKIDAPTLIAVGTKDDIAGSGAELAAIMPHARAIDIPGRDHML
AVGDRVFKAAVLEFYRSL

Sequences:

>Translated_258_residues
MNLNLPQFSDFSHDGLRLAYFDEGDPAGDPVLLIHGFASSANVNWVHPGWVKTLGEAGYRVIAIDNRGHGASDKPHDSEA
YYPSVMAGDAVALLNHLGIAETHVMGYSMGARISAFLAMAHPERVRSLVFGGLGIGMVEGVGDWDPIAEALLAPSLDVVT
HERGRMFRAFADQTKSDRLALAACIETSRVLVTREQAQKIDAPTLIAVGTKDDIAGSGAELAAIMPHARAIDIPGRDHML
AVGDRVFKAAVLEFYRSL
>Mature_258_residues
MNLNLPQFSDFSHDGLRLAYFDEGDPAGDPVLLIHGFASSANVNWVHPGWVKTLGEAGYRVIAIDNRGHGASDKPHDSEA
YYPSVMAGDAVALLNHLGIAETHVMGYSMGARISAFLAMAHPERVRSLVFGGLGIGMVEGVGDWDPIAEALLAPSLDVVT
HERGRMFRAFADQTKSDRLALAACIETSRVLVTREQAQKIDAPTLIAVGTKDDIAGSGAELAAIMPHARAIDIPGRDHML
AVGDRVFKAAVLEFYRSL

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=126, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR022485 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 27685; Mature: 27685

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNLPQFSDFSHDGLRLAYFDEGDPAGDPVLLIHGFASSANVNWVHPGWVKTLGEAGYR
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCEECCHHHHHHHHCCEE
VIAIDNRGHGASDKPHDSEAYYPSVMAGDAVALLNHLGIAETHVMGYSMGARISAFLAMA
EEEEECCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHC
HPERVRSLVFGGLGIGMVEGVGDWDPIAEALLAPSLDVVTHERGRMFRAFADQTKSDRLA
CHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCCHHH
LAACIETSRVLVTREQAQKIDAPTLIAVGTKDDIAGSGAELAAIMPHARAIDIPGRDHML
HHHHHHHHHEEEEHHHHHHCCCCEEEEECCCCCCCCCCCCEEEECCCCEEEECCCCCCEE
AVGDRVFKAAVLEFYRSL
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLNLPQFSDFSHDGLRLAYFDEGDPAGDPVLLIHGFASSANVNWVHPGWVKTLGEAGYR
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCEECCHHHHHHHHCCEE
VIAIDNRGHGASDKPHDSEAYYPSVMAGDAVALLNHLGIAETHVMGYSMGARISAFLAMA
EEEEECCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHC
HPERVRSLVFGGLGIGMVEGVGDWDPIAEALLAPSLDVVTHERGRMFRAFADQTKSDRLA
CHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCCHHH
LAACIETSRVLVTREQAQKIDAPTLIAVGTKDDIAGSGAELAAIMPHARAIDIPGRDHML
HHHHHHHHHEEEEHHHHHHCCCCEEEEECCCCCCCCCCCCEEEECCCCEEEECCCCCCEE
AVGDRVFKAAVLEFYRSL
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8566759; 9387221; 9384377 [H]