Click here to switch to the map view.

The map label for this gene is arsC [H]

Identifier: 159184779

GI number: 159184779

Start: 1479604

End: 1480026

Strand: Reverse

Name: arsC [H]

Synonym: Atu1490

Alternate gene names: 159184779

Gene position: 1480026-1479604 (Counterclockwise)

Preceding gene: 15888816

Following gene: 159184778

Centisome position: 52.08

GC content: 58.16

Gene sequence:

>423_bases
ATGGATGTCACGATTTTTCACAATCCGTCGTGCGGGACGTCTCGCAATACGCTGGCGCTGATCCGGGCGGCGGGGATCGA
GCCGACCGTGGCGGAGTACCTGCAGGAACCGCCGACGCGTGAAAGGCTCGCAAAAATAATTGCCGACGCGGGTCTGACAG
TACGCGAAGCGATACGCGAGAAGGGGACTCCCTATGCCGAACGCGGCCTCGATAATCCGGCCCTAACCGATGATCAACTG
CTCGATGCGATGATGGAAACCCCGATCCTCATCAACCGGCCGTTCGTCATCACACCGCTTGGCACCCGGCTTGCCCGTCC
TTCGGAGGTCGTTCTGGATATTCTGCCCGAAACTTTCAAAGGGCCATTCTTTAAAGAGGATGGCGAGCAGGTCCTCGACA
ATGAAGGAAAGCGCATTGCGTGA

Upstream 100 bases:

>100_bases
CGATCATGCTTTCGGTCGTCTGGATCGTGAACCGCTCGAAGGACTGGTATGAGGCTGCGCCTGCCGTTTCCCGAACGACA
ATCACCGAAAGGCAATGAGT

Downstream 100 bases:

>100_bases
CACATTTCCCTCGCTGCAGGCGCAGCACCTGCACGGAATCGACGAGCAAGCTCTGCGCCCGGCATTTTCGACCCATAAGC
CGCGCATCCTGATCCTATAC

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MDVTIFHNPSCGTSRNTLALIRAAGIEPTVAEYLQEPPTRERLAKIIADAGLTVREAIREKGTPYAERGLDNPALTDDQL
LDAMMETPILINRPFVITPLGTRLARPSEVVLDILPETFKGPFFKEDGEQVLDNEGKRIA

Sequences:

>Translated_140_residues
MDVTIFHNPSCGTSRNTLALIRAAGIEPTVAEYLQEPPTRERLAKIIADAGLTVREAIREKGTPYAERGLDNPALTDDQL
LDAMMETPILINRPFVITPLGTRLARPSEVVLDILPETFKGPFFKEDGEQVLDNEGKRIA
>Mature_140_residues
MDVTIFHNPSCGTSRNTLALIRAAGIEPTVAEYLQEPPTRERLAKIIADAGLTVREAIREKGTPYAERGLDNPALTDDQL
LDAMMETPILINRPFVITPLGTRLARPSEVVLDILPETFKGPFFKEDGEQVLDNEGKRIA

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=138, Percent_Identity=60.1449275362319, Blast_Score=180, Evalue=3e-47,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=37.719298245614, Blast_Score=84, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 15456; Mature: 15456

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVTIFHNPSCGTSRNTLALIRAAGIEPTVAEYLQEPPTRERLAKIIADAGLTVREAIRE
CCEEEEECCCCCCCCCCEEEEHCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHH
KGTPYAERGLDNPALTDDQLLDAMMETPILINRPFVITPLGTRLARPSEVVLDILPETFK
CCCCHHHHCCCCCCCCHHHHHHHHHHCCEEECCCEEEECCCHHHCCHHHHHHHHHHHHHC
GPFFKEDGEQVLDNEGKRIA
CCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MDVTIFHNPSCGTSRNTLALIRAAGIEPTVAEYLQEPPTRERLAKIIADAGLTVREAIRE
CCEEEEECCCCCCCCCCEEEEHCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHH
KGTPYAERGLDNPALTDDQLLDAMMETPILINRPFVITPLGTRLARPSEVVLDILPETFK
CCCCHHHHCCCCCCCCHHHHHHHHHHCCEEECCCEEEECCCHHHCCHHHHHHHHHHHHHC
GPFFKEDGEQVLDNEGKRIA
CCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]