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The map label for this gene is yaeL [C]

Identifier: 159184739

GI number: 159184739

Start: 1373181

End: 1374314

Strand: Direct

Name: yaeL [C]

Synonym: Atu1380

Alternate gene names: 159184739

Gene position: 1373181-1374314 (Clockwise)

Preceding gene: 15888705

Following gene: 15888707

Centisome position: 48.32

GC content: 59.26

Gene sequence:

>1134_bases
ATGAACACAATAATGGCGGCGACGGGCTTTCTGACCGGCTATATAGTGCCCTTTATACTGGTGCTTTCCCTGCTCGTTTT
CGTTCATGAGATGGGGCATTACCTTGTCGGCCGCTGGTGCGGCATCCGATCCACCGCATTCTCCATCGGCTTCGGCCCCG
AGCTCATCGGTTTCACCGACAAGCGCGGCACGCGATGGAAGCTTTCGGCAATTCCGCTCGGCGGCTATGTCAAGTTCTTT
GGCGACGAAGATGCGGCGAGCAAGTCGGATAGTTCCGGCCTGTCGCATATGTCGCTGGAGGAGAGGGCGCAGACGCTTTC
CGGCGCAAAGCTGTGGAAAAGGGCGGCCACGGTTGCTGCCGGCCCGATTGCAAATTTCATTCTCGCAATTCTCATTTTTG
CGGTGCTTTTCGGCATCTACGGCCGGATGATCGCTGATCCTGTCGTGGCGGAGGTGCGTGAAAACAGCGCCGCCGCAACA
GCCGGCGTAAAACCCGGCGACCGGCTGGTGGCGATCGATGGCGAAAAAGTGATGACCTTCGAGGATGTCCGCCGTTATGT
CGGCATCAGGCCGGGCACGCCGATTACGGTAACCGTCGAAAGGGCAGGCGAGGAACTCAAGCTGCCTATGGTCCCGACCC
GTACCGAAACCACAGACCAGTTCGGTAACAAGCTGGAAATGGGTATCATCGGCATCGTCACCGACCAGACCAGCGGCAAT
TTCCGGCACATCGAATATTCGCCGTCAGAGGCGGTGGCTGAGGGCGTGCGCGAAACGGGCCACGTCATCACCGGCACTTT
CAACTATATCGGCAATCTCGTGACAGGGCGCATGAATGCCGATCAGCTCGGTGGCCCCGTGCGTGTCGCGCAGGCATCCG
GCCAGATGGCGACGCTCGGCATTTCCGCCGTTATCCAGCTCGCCGCCGTCCTTTCCGTCTCGATCGGTCTGTTGAACCTC
ATGCCTGTTCCGGTGCTGGACGGTGGCCATCTGGTATTCTACGCCATCGAGGCCATCCGCGGCAGGCCGCTCGGTGCGGG
GGCGCAGGAAGTGGCGTTCCGTATCGGCATGATGATGATTCTGGGTCTGATGGTTTTTGCAACATGGAATGATATCAGCA
GCTTGATCGGCTGA

Upstream 100 bases:

>100_bases
GTGCATGCGGCGGCAACCGGAGACGTGCCCGGATCGGGCGGCGGTCTGCTGCCGGGTTTCTAGGCGTCGCGATAGGTCAC
GACATAAAGGGCAGATTGTC

Downstream 100 bases:

>100_bases
GGATTGTGTTTTAACGGTTTTGTTAGTTATTTGTTTACCGTGTTTTTATGCCGAAGTGGCGAATGAGCCACTCTGGAGCA
CGAAGTAAACAGAATTTAAC

Product: zinc metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MNTIMAATGFLTGYIVPFILVLSLLVFVHEMGHYLVGRWCGIRSTAFSIGFGPELIGFTDKRGTRWKLSAIPLGGYVKFF
GDEDAASKSDSSGLSHMSLEERAQTLSGAKLWKRAATVAAGPIANFILAILIFAVLFGIYGRMIADPVVAEVRENSAAAT
AGVKPGDRLVAIDGEKVMTFEDVRRYVGIRPGTPITVTVERAGEELKLPMVPTRTETTDQFGNKLEMGIIGIVTDQTSGN
FRHIEYSPSEAVAEGVRETGHVITGTFNYIGNLVTGRMNADQLGGPVRVAQASGQMATLGISAVIQLAAVLSVSIGLLNL
MPVPVLDGGHLVFYAIEAIRGRPLGAGAQEVAFRIGMMMILGLMVFATWNDISSLIG

Sequences:

>Translated_377_residues
MNTIMAATGFLTGYIVPFILVLSLLVFVHEMGHYLVGRWCGIRSTAFSIGFGPELIGFTDKRGTRWKLSAIPLGGYVKFF
GDEDAASKSDSSGLSHMSLEERAQTLSGAKLWKRAATVAAGPIANFILAILIFAVLFGIYGRMIADPVVAEVRENSAAAT
AGVKPGDRLVAIDGEKVMTFEDVRRYVGIRPGTPITVTVERAGEELKLPMVPTRTETTDQFGNKLEMGIIGIVTDQTSGN
FRHIEYSPSEAVAEGVRETGHVITGTFNYIGNLVTGRMNADQLGGPVRVAQASGQMATLGISAVIQLAAVLSVSIGLLNL
MPVPVLDGGHLVFYAIEAIRGRPLGAGAQEVAFRIGMMMILGLMVFATWNDISSLIG
>Mature_377_residues
MNTIMAATGFLTGYIVPFILVLSLLVFVHEMGHYLVGRWCGIRSTAFSIGFGPELIGFTDKRGTRWKLSAIPLGGYVKFF
GDEDAASKSDSSGLSHMSLEERAQTLSGAKLWKRAATVAAGPIANFILAILIFAVLFGIYGRMIADPVVAEVRENSAAAT
AGVKPGDRLVAIDGEKVMTFEDVRRYVGIRPGTPITVTVERAGEELKLPMVPTRTETTDQFGNKLEMGIIGIVTDQTSGN
FRHIEYSPSEAVAEGVRETGHVITGTFNYIGNLVTGRMNADQLGGPVRVAQASGQMATLGISAVIQLAAVLSVSIGLLNL
MPVPVLDGGHLVFYAIEAIRGRPLGAGAQEVAFRIGMMMILGLMVFATWNDISSLIG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1786373, Length=233, Percent_Identity=34.3347639484979, Blast_Score=141, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1380_AGRT5 (Q8UFL7)

Other databases:

- EMBL:   AE007869
- PIR:   AD2746
- PIR:   C97527
- RefSeq:   NP_354387.2
- ProteinModelPortal:   Q8UFL7
- SMR:   Q8UFL7
- STRING:   Q8UFL7
- MEROPS:   M50.004
- GeneID:   1133418
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1380
- eggNOG:   COG0750
- HOGENOM:   HBG664087
- OMA:   HGTEFVV
- PhylomeDB:   Q8UFL7
- ProtClustDB:   CLSK800344
- BioCyc:   ATUM176299-1:ATU1380-MONOMER
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915
- SMART:   SM00228
- TIGRFAMs:   TIGR00054

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50; SSF50156 PDZ

EC number: NA

Molecular weight: Translated: 40225; Mature: 40225

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50106 PDZ; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 30-30

Signals:

None

Transmembrane regions:

HASH(0xea2ed80)-; HASH(0xe4c62e0)-; HASH(0xe4f4d80)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIMAATGFLTGYIVPFILVLSLLVFVHEMGHYLVGRWCGIRSTAFSIGFGPELIGFTD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCHHCEEEC
KRGTRWKLSAIPLGGYVKFFGDEDAASKSDSSGLSHMSLEERAQTLSGAKLWKRAATVAA
CCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GPIANFILAILIFAVLFGIYGRMIADPVVAEVRENSAAATAGVKPGDRLVAIDGEKVMTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCEEEEECCCEEEEH
EDVRRYVGIRPGTPITVTVERAGEELKLPMVPTRTETTDQFGNKLEMGIIGIVTDQTSGN
HHHHHHHCCCCCCCEEEEEECCCCEEECCCCCCCCCCHHHHCCEEEEEEEEEEEECCCCC
FRHIEYSPSEAVAEGVRETGHVITGTFNYIGNLVTGRMNADQLGGPVRVAQASGQMATLG
EEEEEECCHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHCCCCEEEEECCCCEEHHH
ISAVIQLAAVLSVSIGLLNLMPVPVLDGGHLVFYAIEAIRGRPLGAGAQEVAFRIGMMMI
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHHH
LGLMVFATWNDISSLIG
HHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNTIMAATGFLTGYIVPFILVLSLLVFVHEMGHYLVGRWCGIRSTAFSIGFGPELIGFTD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCHHCEEEC
KRGTRWKLSAIPLGGYVKFFGDEDAASKSDSSGLSHMSLEERAQTLSGAKLWKRAATVAA
CCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GPIANFILAILIFAVLFGIYGRMIADPVVAEVRENSAAATAGVKPGDRLVAIDGEKVMTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCEEEEECCCEEEEH
EDVRRYVGIRPGTPITVTVERAGEELKLPMVPTRTETTDQFGNKLEMGIIGIVTDQTSGN
HHHHHHHCCCCCCCEEEEEECCCCEEECCCCCCCCCCHHHHCCEEEEEEEEEEEECCCCC
FRHIEYSPSEAVAEGVRETGHVITGTFNYIGNLVTGRMNADQLGGPVRVAQASGQMATLG
EEEEEECCHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHCCCCEEEEECCCCEEHHH
ISAVIQLAAVLSVSIGLLNLMPVPVLDGGHLVFYAIEAIRGRPLGAGAQEVAFRIGMMMI
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHHH
LGLMVFATWNDISSLIG
HHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194