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The map label for this gene is ubiE [C]

Identifier: 159184287

GI number: 159184287

Start: 382964

End: 383776

Strand: Direct

Name: ubiE [C]

Synonym: Atu0390

Alternate gene names: 159184287

Gene position: 382964-383776 (Clockwise)

Preceding gene: 15887738

Following gene: 159184288

Centisome position: 13.48

GC content: 58.18

Gene sequence:

>813_bases
ATGTTGGAAGCGGACAAGGTGTTTGCGGGTTCGATTCCGGAGAATTACGACCGCTATATGGTGCCGTTGATCTTTGCGCC
ATTCGCTGCTGATCTGGCGCGGCGCGCGGCTGCCTTGATGCCGATTGACGTTCTGGAAATCGCCGCGGGCACCGGGGCCG
TCACGCGGGAAATGATTCCCCGATTATTGCCAGCGGCACATTACGTGGTGACCGACCTCAATCAGCCGATGCTCGATTTT
GCAGCAGCGCAACAGGCACCCGACAACCGCATAAAATGGCGACAGGCGGATGCTCAGCTTCTGCCTTTTGAAAATGCTGT
TTTCGATCTGGTTTTCTGTCAGTTCGGTGCAATGTTCTTTAACGATCGCCTGTCCGCCTATCGTGAGGCAAAGCGGGTGT
TGAAGCCCGGCGGGCACTATTTATTCAACGTATGGGATCGCATCGAGGAAAATCACTTCGCGGATGATGTGACGAACGCC
CTTGCCGGGCTTTTCCCCGATGATCCCCCGCGCTTCATGGCCCGCACCCCACACGGTTATCATGATACGGTGTTGATACG
CCGCGAGTTGGAGAATGCCGGTTTTTCCCGTGTGACCGTCGAGACGGTGGCGGCGCAAAGCCGCGCCCCGTCACCGCGCA
TTCCGGCCGTCGCCTATTGTCAGGGAACGGTTCTGCGGACGGAAATAGAGGCGAGGGCACCGGGGAAGCTCAATGCAGCG
ACTGATTGTGCCGCTGCCGCGATTGAAGCCCGGCATGGTAAGGGCGAGGTGGCAGCCAAGATTAAGGCTCATGTGATTCT
CGCCGCCGTGTAG

Upstream 100 bases:

>100_bases
GCCTGCGTTGATGTCGAAGCCCCGTAAGGCCGAATGAATTCCGATCATCCCGAATATATGTTAAAGTCTTCCGCTCATCA
GATGGCCCGGAGTGAAAGCC

Downstream 100 bases:

>100_bases
ATCGGAGCCACCGACCCGGTTTTCCAGCCGATGGAGGCGTGCTGAAAACACGTCGGAATATCCCCCTAAATATTAGTGGC
TTTAGGTGGAGGTCTATACC

Product: ubiquinone/menaquinone biosynthesis methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Ubiquinone/Menaquinone Biosynthesis Methyltransferase; Methyltransferase; SAM-Dependent Methyltransferase; UbiE/COQ5 Methyltransferase; Methyltransferase Protein; Methyltransferase UbiE/COQ5 Family; Ubiquinone/Menaquinone Biosynthesis Methyltransferase UbiE; S-Adenosyl-L-Methionine-Dependent Methyltransferase; UbiE/COQ5 Family Methlytransferase; UbiE/COQ5 Methyltransferase Family; Menaquinone Biosynthesis Methyltransferase

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MLEADKVFAGSIPENYDRYMVPLIFAPFAADLARRAAALMPIDVLEIAAGTGAVTREMIPRLLPAAHYVVTDLNQPMLDF
AAAQQAPDNRIKWRQADAQLLPFENAVFDLVFCQFGAMFFNDRLSAYREAKRVLKPGGHYLFNVWDRIEENHFADDVTNA
LAGLFPDDPPRFMARTPHGYHDTVLIRRELENAGFSRVTVETVAAQSRAPSPRIPAVAYCQGTVLRTEIEARAPGKLNAA
TDCAAAAIEARHGKGEVAAKIKAHVILAAV

Sequences:

>Translated_270_residues
MLEADKVFAGSIPENYDRYMVPLIFAPFAADLARRAAALMPIDVLEIAAGTGAVTREMIPRLLPAAHYVVTDLNQPMLDF
AAAQQAPDNRIKWRQADAQLLPFENAVFDLVFCQFGAMFFNDRLSAYREAKRVLKPGGHYLFNVWDRIEENHFADDVTNA
LAGLFPDDPPRFMARTPHGYHDTVLIRRELENAGFSRVTVETVAAQSRAPSPRIPAVAYCQGTVLRTEIEARAPGKLNAA
TDCAAAAIEARHGKGEVAAKIKAHVILAAV
>Mature_270_residues
MLEADKVFAGSIPENYDRYMVPLIFAPFAADLARRAAALMPIDVLEIAAGTGAVTREMIPRLLPAAHYVVTDLNQPMLDF
AAAQQAPDNRIKWRQADAQLLPFENAVFDLVFCQFGAMFFNDRLSAYREAKRVLKPGGHYLFNVWDRIEENHFADDVTNA
LAGLFPDDPPRFMARTPHGYHDTVLIRRELENAGFSRVTVETVAAQSRAPSPRIPAVAYCQGTVLRTEIEARAPGKLNAA
TDCAAAAIEARHGKGEVAAKIKAHVILAAV

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29685; Mature: 29685

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEADKVFAGSIPENYDRYMVPLIFAPFAADLARRAAALMPIDVLEIAAGTGAVTREMIP
CCCCCCEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHH
RLLPAAHYVVTDLNQPMLDFAAAQQAPDNRIKWRQADAQLLPFENAVFDLVFCQFGAMFF
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCCEECCCHHHHHHHHHHHHHHHHH
NDRLSAYREAKRVLKPGGHYLFNVWDRIEENHFADDVTNALAGLFPDDPPRFMARTPHGY
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCC
HDTVLIRRELENAGFSRVTVETVAAQSRAPSPRIPAVAYCQGTVLRTEIEARAPGKLNAA
CHHEEEEEHHHCCCCCEEHHHHHHHHCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCCH
TDCAAAAIEARHGKGEVAAKIKAHVILAAV
HHHHHHHHHHCCCCCHHHHHEEEEEEEEEC
>Mature Secondary Structure
MLEADKVFAGSIPENYDRYMVPLIFAPFAADLARRAAALMPIDVLEIAAGTGAVTREMIP
CCCCCCEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHH
RLLPAAHYVVTDLNQPMLDFAAAQQAPDNRIKWRQADAQLLPFENAVFDLVFCQFGAMFF
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCCEECCCHHHHHHHHHHHHHHHHH
NDRLSAYREAKRVLKPGGHYLFNVWDRIEENHFADDVTNALAGLFPDDPPRFMARTPHGY
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCC
HDTVLIRRELENAGFSRVTVETVAAQSRAPSPRIPAVAYCQGTVLRTEIEARAPGKLNAA
CHHEEEEEHHHCCCCCEEHHHHHHHHCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCCH
TDCAAAAIEARHGKGEVAAKIKAHVILAAV
HHHHHHHHHHCCCCCHHHHHEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA