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The map label for this gene is mcpA [H]

Identifier: 159184278

GI number: 159184278

Start: 366973

End: 369300

Strand: Direct

Name: mcpA [H]

Synonym: Atu0373

Alternate gene names: 159184278

Gene position: 366973-369300 (Clockwise)

Preceding gene: 15887723

Following gene: 15887726

Centisome position: 12.91

GC content: 61.0

Gene sequence:

>2328_bases
ATGTTCAATTTCAAAGTGAAGTCGCTTGCGACGAAGCTCATCCTCGTGACCGGCTGCGCCATCACCACGGTTCTTATCGC
ATCGAATTCCTTCCTCATTTCCCAGACCAGTGAACGTGTCCATGCCCTGACCATGGATCAGGCCAATACCGAGGCGCGCG
CCATCGCCAACGTCATTGCCGCCGATGTCGGCGAACTCGGCAGCGCGGCGCGCTCAATGGCCGGTGTCATCGGCCGTGCG
CATCAGGCTAAGTCGATGGACCGGCCTGGTATCGTCAATATCCTCAAAGCGAATGTCGAGCAGAATACGTTCGCCTTCGG
CAGCTGGTTCTGCGAGCAGCTCGGCCTTTTTGACGGCCAGTCGACGGAGATCGCTAACCGGCTCGATCTCGGCACCAATA
AAAGCGGTGCTTTTGCCCCTTATTGGTCAAAGACCCAGAAGGGCGATATCCAGTTTTCGACCTTCGACAACGACTATGCG
GCCGAATGGTACGCGCTAGCCTCCAAATCCGGCAAGGGAGCCATCACCCAGCCTTACCTCGCCCAGGGCACGGAAGTGCC
CACCACCATGACCTCGCTCGCCTATCCCGTCATGTCGGATGGCAAGATGATCGGCGTGGCAGGTGTCGATATTTCGCTCG
CCTCGCTCACCCAGAAACTGCAGGCTCTGCATCCTTTTGAAACCGGCCGCGTGACGCTCGTTTCCCAGGGTGGGCAGTGG
CTGGTGCCGCCGACCCCCGAGCAGAATATGAAGGCTTACGACGGAGAAGGCGCAAGCACCGTTCAGGCTGCCATCACCTC
CGGCAAACAGGGCCTCATCGAAAATCTCGGCCTCGACACCGACGCGCCCTATAACCGTCTCGTTTATCCCTTCGCCGTTC
CAGGCCTCAACGCGACGTGGGTCGTTCTGGTGGATATCCCCCATCAGGCGTTGAATGCTCCGGTACAGGAGCAGACCTTT
ATGATGATCATCGGTGCGATCGTCATTCTCGCCGCCGTTATTGCCGCGCTTTATTTTGCGGTTCGCTATTTCGTTCGCAA
CCCGCTCGCGTCCCTTGTTGCCGATGTCAGGACGCTCAGTGAGGGTCGCTACGATGTGCCGGTGTCCGGTCAGGAACGTC
AGGACGAAACTGGAGCCGTGGCGTCTGCTCTCGAAGGTTTCCGCGCAAAGCTTGCCGGCATCCGCGAGATGGAAGCTGAA
GCCGCCGCCCAGCGTGGCCATGCGGAGACGGAACGCCAGCGATCGGAGTTCGAGCGTAGCGAGAATAGCCGCATGCAGCA
GCACATTGTCGGCGTGCTTGGTGCCGGCCTCAATGCGCTTTCGCAAGGCAATCTGACCTACCGTATCGAGGATGAATTCC
CAGGCGAATATGCAAAGCTGCGCGCTGATTTCAACTCGGCGCTCGAAAGCCTCGAGGAAACGGTGTCAACCGTCAACGCC
ACCGTCGTCAGTATCGGCAATGGTACCGGCGAGATCACCCGCGCCGCCAGCGATCTCTCGCATCGCACGGAACAGCAGGC
TGCAAGTCTGGAGGAAACCGCCGCGGCCCTCAACGAGTTGACCGCACAGGTCAATTCCAGCGCGGAAAACGCCGCAGAGG
CGGCCGGTGCCGTCAGCCATGCCTGCGATGACGCCGGCAAGTCAGGCGAGGTCGTGCAGCAGGCCGTGAACTCCATGCAG
GGCATCGCGCAATCCTCGGCGGAAATCTCCCGTATCATCGGGGTGATCGACGAGATCGCCTTCCAGACCAATCTGCTGGC
GCTGAATGCCGGTGTTGAAGCGGCTCGCGCAGGCGATGCGGGCAAGGGCTTTGCGGTCGTCGCGCAGGAAGTGCGTGAAC
TCGCGCAACGCTCCGCCACTGCCGCCAAGGAAATCAAGGGCCTGATAAACACGTCGGCCACGCAGGTGGGCGAGGGTGTC
CAGCTGGTCGGCAAGGCCGGCGAGACAATGAAAAAGATCGCCGATCAGGTTCTGCAGATCAACCAGCTGATACGGCAGAT
CTCCGCCTCGGCCAGCGAGCAGGCGGTAGGACTGAAGGAAATCAACTCCGCCGTGACCCAGATGGATCAGGTCACCCAGC
AGAATGCGGCGATGGTGGAGGAAACCACTGCAGCTAGCGTGACGCTGAACAGCGAAGCCGAAACCCTGAAATCGCTCGTT
GCCGGTTTCGCGGTGTCCGGCGGCCATGCGAGCCAGCAATTGCGCGCCACGGCAGCGACAATGCGTGCACCGGCCGCTCC
GGCAAGGGCGCAGGCCGCGGCTCCTCGTGCCCGTCCGAGAACCAGCGGCGCAAACGCGCTGGCGCAGGATGACTGGACGG
AATTCTGA

Upstream 100 bases:

>100_bases
GCGCTGCAGCGCACTGTCCCATGCGGACGGGCCTCCATGACGGAGATTGTCATCCGTTGACGTCAGCTCTTTCGGGTTGA
CAATTTCCATTGGGGCCAAG

Downstream 100 bases:

>100_bases
TCCGCCATTCCCGCTGAAAATAAAAGGGCCGCTGGCTTTTCCAGCGGCCTTTTTTTGTTCCTGTCCGGATCAGAGCCGGG
CGAAACGTTCGGTCAGCAAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 775; Mature: 775

Protein sequence:

>775_residues
MFNFKVKSLATKLILVTGCAITTVLIASNSFLISQTSERVHALTMDQANTEARAIANVIAADVGELGSAARSMAGVIGRA
HQAKSMDRPGIVNILKANVEQNTFAFGSWFCEQLGLFDGQSTEIANRLDLGTNKSGAFAPYWSKTQKGDIQFSTFDNDYA
AEWYALASKSGKGAITQPYLAQGTEVPTTMTSLAYPVMSDGKMIGVAGVDISLASLTQKLQALHPFETGRVTLVSQGGQW
LVPPTPEQNMKAYDGEGASTVQAAITSGKQGLIENLGLDTDAPYNRLVYPFAVPGLNATWVVLVDIPHQALNAPVQEQTF
MMIIGAIVILAAVIAALYFAVRYFVRNPLASLVADVRTLSEGRYDVPVSGQERQDETGAVASALEGFRAKLAGIREMEAE
AAAQRGHAETERQRSEFERSENSRMQQHIVGVLGAGLNALSQGNLTYRIEDEFPGEYAKLRADFNSALESLEETVSTVNA
TVVSIGNGTGEITRAASDLSHRTEQQAASLEETAAALNELTAQVNSSAENAAEAAGAVSHACDDAGKSGEVVQQAVNSMQ
GIAQSSAEISRIIGVIDEIAFQTNLLALNAGVEAARAGDAGKGFAVVAQEVRELAQRSATAAKEIKGLINTSATQVGEGV
QLVGKAGETMKKIADQVLQINQLIRQISASASEQAVGLKEINSAVTQMDQVTQQNAAMVEETTAASVTLNSEAETLKSLV
AGFAVSGGHASQQLRATAATMRAPAAPARAQAAAPRARPRTSGANALAQDDWTEF

Sequences:

>Translated_775_residues
MFNFKVKSLATKLILVTGCAITTVLIASNSFLISQTSERVHALTMDQANTEARAIANVIAADVGELGSAARSMAGVIGRA
HQAKSMDRPGIVNILKANVEQNTFAFGSWFCEQLGLFDGQSTEIANRLDLGTNKSGAFAPYWSKTQKGDIQFSTFDNDYA
AEWYALASKSGKGAITQPYLAQGTEVPTTMTSLAYPVMSDGKMIGVAGVDISLASLTQKLQALHPFETGRVTLVSQGGQW
LVPPTPEQNMKAYDGEGASTVQAAITSGKQGLIENLGLDTDAPYNRLVYPFAVPGLNATWVVLVDIPHQALNAPVQEQTF
MMIIGAIVILAAVIAALYFAVRYFVRNPLASLVADVRTLSEGRYDVPVSGQERQDETGAVASALEGFRAKLAGIREMEAE
AAAQRGHAETERQRSEFERSENSRMQQHIVGVLGAGLNALSQGNLTYRIEDEFPGEYAKLRADFNSALESLEETVSTVNA
TVVSIGNGTGEITRAASDLSHRTEQQAASLEETAAALNELTAQVNSSAENAAEAAGAVSHACDDAGKSGEVVQQAVNSMQ
GIAQSSAEISRIIGVIDEIAFQTNLLALNAGVEAARAGDAGKGFAVVAQEVRELAQRSATAAKEIKGLINTSATQVGEGV
QLVGKAGETMKKIADQVLQINQLIRQISASASEQAVGLKEINSAVTQMDQVTQQNAAMVEETTAASVTLNSEAETLKSLV
AGFAVSGGHASQQLRATAATMRAPAAPARAQAAAPRARPRTSGANALAQDDWTEF
>Mature_775_residues
MFNFKVKSLATKLILVTGCAITTVLIASNSFLISQTSERVHALTMDQANTEARAIANVIAADVGELGSAARSMAGVIGRA
HQAKSMDRPGIVNILKANVEQNTFAFGSWFCEQLGLFDGQSTEIANRLDLGTNKSGAFAPYWSKTQKGDIQFSTFDNDYA
AEWYALASKSGKGAITQPYLAQGTEVPTTMTSLAYPVMSDGKMIGVAGVDISLASLTQKLQALHPFETGRVTLVSQGGQW
LVPPTPEQNMKAYDGEGASTVQAAITSGKQGLIENLGLDTDAPYNRLVYPFAVPGLNATWVVLVDIPHQALNAPVQEQTF
MMIIGAIVILAAVIAALYFAVRYFVRNPLASLVADVRTLSEGRYDVPVSGQERQDETGAVASALEGFRAKLAGIREMEAE
AAAQRGHAETERQRSEFERSENSRMQQHIVGVLGAGLNALSQGNLTYRIEDEFPGEYAKLRADFNSALESLEETVSTVNA
TVVSIGNGTGEITRAASDLSHRTEQQAASLEETAAALNELTAQVNSSAENAAEAAGAVSHACDDAGKSGEVVQQAVNSMQ
GIAQSSAEISRIIGVIDEIAFQTNLLALNAGVEAARAGDAGKGFAVVAQEVRELAQRSATAAKEIKGLINTSATQVGEGV
QLVGKAGETMKKIADQVLQINQLIRQISASASEQAVGLKEINSAVTQMDQVTQQNAAMVEETTAASVTLNSEAETLKSLV
AGFAVSGGHASQQLRATAATMRAPAAPARAQAAAPRARPRTSGANALAQDDWTEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=310, Percent_Identity=44.5161290322581, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1788195, Length=342, Percent_Identity=43.2748538011696, Blast_Score=215, Evalue=8e-57,
Organism=Escherichia coli, GI1787690, Length=287, Percent_Identity=44.5993031358885, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI2367378, Length=309, Percent_Identity=46.6019417475728, Blast_Score=207, Evalue=3e-54,
Organism=Escherichia coli, GI1789453, Length=246, Percent_Identity=41.869918699187, Blast_Score=174, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 81716; Mature: 81716

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNFKVKSLATKLILVTGCAITTVLIASNSFLISQTSERVHALTMDQANTEARAIANVIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHEEECCCCCHHHHHHHHHHH
ADVGELGSAARSMAGVIGRAHQAKSMDRPGIVNILKANVEQNTFAFGSWFCEQLGLFDGQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
STEIANRLDLGTNKSGAFAPYWSKTQKGDIQFSTFDNDYAAEWYALASKSGKGAITQPYL
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCHH
AQGTEVPTTMTSLAYPVMSDGKMIGVAGVDISLASLTQKLQALHPFETGRVTLVSQGGQW
HCCCCCCHHHHHHHCHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECCCEE
LVPPTPEQNMKAYDGEGASTVQAAITSGKQGLIENLGLDTDAPYNRLVYPFAVPGLNATW
CCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCEE
VVLVDIPHQALNAPVQEQTFMMIIGAIVILAAVIAALYFAVRYFVRNPLASLVADVRTLS
EEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHC
EGRYDVPVSGQERQDETGAVASALEGFRAKLAGIREMEAEAAAQRGHAETERQRSEFERS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ENSRMQQHIVGVLGAGLNALSQGNLTYRIEDEFPGEYAKLRADFNSALESLEETVSTVNA
HHHHHHHHHHHHHHHCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVSIGNGTGEITRAASDLSHRTEQQAASLEETAAALNELTAQVNSSAENAAEAAGAVSH
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ACDDAGKSGEVVQQAVNSMQGIAQSSAEISRIIGVIDEIAFQTNLLALNAGVEAARAGDA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHCCCCC
GKGFAVVAQEVRELAQRSATAAKEIKGLINTSATQVGEGVQLVGKAGETMKKIADQVLQI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCHHHHHHHHHHHHH
NQLIRQISASASEQAVGLKEINSAVTQMDQVTQQNAAMVEETTAASVTLNSEAETLKSLV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHH
AGFAVSGGHASQQLRATAATMRAPAAPARAQAAAPRARPRTSGANALAQDDWTEF
HHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFNFKVKSLATKLILVTGCAITTVLIASNSFLISQTSERVHALTMDQANTEARAIANVIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHEEECCCCCHHHHHHHHHHH
ADVGELGSAARSMAGVIGRAHQAKSMDRPGIVNILKANVEQNTFAFGSWFCEQLGLFDGQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
STEIANRLDLGTNKSGAFAPYWSKTQKGDIQFSTFDNDYAAEWYALASKSGKGAITQPYL
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCHH
AQGTEVPTTMTSLAYPVMSDGKMIGVAGVDISLASLTQKLQALHPFETGRVTLVSQGGQW
HCCCCCCHHHHHHHCHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECCCEE
LVPPTPEQNMKAYDGEGASTVQAAITSGKQGLIENLGLDTDAPYNRLVYPFAVPGLNATW
CCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCEE
VVLVDIPHQALNAPVQEQTFMMIIGAIVILAAVIAALYFAVRYFVRNPLASLVADVRTLS
EEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHC
EGRYDVPVSGQERQDETGAVASALEGFRAKLAGIREMEAEAAAQRGHAETERQRSEFERS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ENSRMQQHIVGVLGAGLNALSQGNLTYRIEDEFPGEYAKLRADFNSALESLEETVSTVNA
HHHHHHHHHHHHHHHCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVSIGNGTGEITRAASDLSHRTEQQAASLEETAAALNELTAQVNSSAENAAEAAGAVSH
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ACDDAGKSGEVVQQAVNSMQGIAQSSAEISRIIGVIDEIAFQTNLLALNAGVEAARAGDA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHCCCCC
GKGFAVVAQEVRELAQRSATAAKEIKGLINTSATQVGEGVQLVGKAGETMKKIADQVLQI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCHHHHHHHHHHHHH
NQLIRQISASASEQAVGLKEINSAVTQMDQVTQQNAAMVEETTAASVTLNSEAETLKSLV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHH
AGFAVSGGHASQQLRATAATMRAPAAPARAQAAAPRARPRTSGANALAQDDWTEF
HHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]