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The map label for this gene is cycY [H]

Identifier: 159046590

GI number: 159046590

Start: 112312

End: 112878

Strand: Direct

Name: cycY [H]

Synonym: Dshi_4052

Alternate gene names: 159046590

Gene position: 112312-112878 (Clockwise)

Preceding gene: 159046589

Following gene: 159046591

Centisome position: 88.92

GC content: 60.67

Gene sequence:

>567_bases
ATGAAACGTCTCATTGCCGGGCTGCCGTTTATTGCGGCGGTCATATTCGGTGGGTTTTTTCTCTGGGGGCTCAATCCCGA
CCGGGATCCCAACGAGATCCCTTCCGTCCTGATCTCGCAACCGGCCCCGGCGTTCGACCTCGATCCCGTGCCGGGGTTGG
AGACACCCGGCCTGGCCCGAAGCGATCTTGTCGGCAACGAACGACCGGTCGTGGTCAATGTCTTTGCGTCCTGGTGCGTG
CCCTGCCGCGCGGAACATGCCGTGTTGACAAGATTTGTCGAACGAGACGGCATGCGGTTGTTCGGAATAAACTACAAAGA
CAAACCTGAGGATGCCGTGAAGTGGCTCAATGACCTCGGCAATCCCTACGAGCGGATCGGGTCCGACCTGTCGGGCCGGA
CCGGGATCGAATGGGGCCTGTCGGGCGTGCCGGAAACCTTCATCGTCGATAGCGATGGCACCGTTTTGTTTCGCTATGTC
GGGCCGGTCGTGGGTCCGGACGCCGTCGAACGGTTCACGCAAGCCCTGAAGCAGGCAGGCGCACTGCCAAATGGAGCAGG
TTCATGA

Upstream 100 bases:

>100_bases
GTGGCTGTTTGTCCTTGTCGGATCGCCGTTTGAGGGTCGGGGCGCCGCGCCGTGCCAAACAGCCAGCCACCGATGCCGTT
CCTGCCGAGTAGGAGAGAAG

Downstream 100 bases:

>100_bases
GACAGTTGATTTTCGCGTTTTGCATCGGGCTCCTTCCCTTTGCCGCCAATGCGGTGGAACCGGACGAAATGCTGACCGAC
CCGGTATTGGAACAGCGTGC

Product: periplasmic protein thiol--disulphide oxidoreductase DsbE

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CycY [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKRLIAGLPFIAAVIFGGFFLWGLNPDRDPNEIPSVLISQPAPAFDLDPVPGLETPGLARSDLVGNERPVVVNVFASWCV
PCRAEHAVLTRFVERDGMRLFGINYKDKPEDAVKWLNDLGNPYERIGSDLSGRTGIEWGLSGVPETFIVDSDGTVLFRYV
GPVVGPDAVERFTQALKQAGALPNGAGS

Sequences:

>Translated_188_residues
MKRLIAGLPFIAAVIFGGFFLWGLNPDRDPNEIPSVLISQPAPAFDLDPVPGLETPGLARSDLVGNERPVVVNVFASWCV
PCRAEHAVLTRFVERDGMRLFGINYKDKPEDAVKWLNDLGNPYERIGSDLSGRTGIEWGLSGVPETFIVDSDGTVLFRYV
GPVVGPDAVERFTQALKQAGALPNGAGS
>Mature_188_residues
MKRLIAGLPFIAAVIFGGFFLWGLNPDRDPNEIPSVLISQPAPAFDLDPVPGLETPGLARSDLVGNERPVVVNVFASWCV
PCRAEHAVLTRFVERDGMRLFGINYKDKPEDAVKWLNDLGNPYERIGSDLSGRTGIEWGLSGVPETFIVDSDGTVLFRYV
GPVVGPDAVERFTQALKQAGALPNGAGS

Specific function: Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur [

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=165, Percent_Identity=37.5757575757576, Blast_Score=120, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 20321; Mature: 20321

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLIAGLPFIAAVIFGGFFLWGLNPDRDPNEIPSVLISQPAPAFDLDPVPGLETPGLAR
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
SDLVGNERPVVVNVFASWCVPCRAEHAVLTRFVERDGMRLFGINYKDKPEDAVKWLNDLG
HHCCCCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCC
NPYERIGSDLSGRTGIEWGLSGVPETFIVDSDGTVLFRYVGPVVGPDAVERFTQALKQAG
CHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHC
ALPNGAGS
CCCCCCCC
>Mature Secondary Structure
MKRLIAGLPFIAAVIFGGFFLWGLNPDRDPNEIPSVLISQPAPAFDLDPVPGLETPGLAR
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
SDLVGNERPVVVNVFASWCVPCRAEHAVLTRFVERDGMRLFGINYKDKPEDAVKWLNDLG
HHCCCCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCC
NPYERIGSDLSGRTGIEWGLSGVPETFIVDSDGTVLFRYVGPVVGPDAVERFTQALKQAG
CHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHC
ALPNGAGS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]