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The map label for this gene is ompR [H]

Identifier: 159046586

GI number: 159046586

Start: 107808

End: 108530

Strand: Direct

Name: ompR [H]

Synonym: Dshi_4048

Alternate gene names: 159046586

Gene position: 107808-108530 (Clockwise)

Preceding gene: 159046578

Following gene: 159046587

Centisome position: 85.36

GC content: 59.89

Gene sequence:

>723_bases
ATGGGACCGCCACCTCATATCCTTATCGTGGACGACCACGCTCAGATACGCGAAAGCGTCGCGCGCTTCCTGGAGAAGAA
CGGAATGCGCACGACCGTCGCCAGGGATGCCGTGGAGATGGATGCCAAGCTGGCCACTGGTCACTTCGACCTCCTCGTGC
TCGATGTCATGATGCCGGGCGAGGACGGTTTGTCGGTTTGCCGCAGACTTGCGCCAGAGGGTGATCTTCCGATCATCATG
CTGACGGCGCTTGGTGAGGAAACGGATCGGATCGTGGGTCTGGAAATCGGTGCGGACGATTATCTCGCCAAGCCGTTCAA
TCCACGAGAACTGCTCGCCCGCATCAAGTCGGTTCTTCGGAGAAGCAACCGCGACGAACCTGTGGCCGGAAGCCTCGCTG
GGAGGAAAGTCTCTTTTGCGCACTGGATACTGGATACCGACCGGCAGGTGCTGATTGACGAGTCCACCACCGAGACCCCA
TTGACGACCTCCGAGTTCAAATTGCTGGCGGTCCTGCTGGAACGCGCGAGGATGGTGCTCAGCCGTGACCAGTTGCTTGA
CCTGACCGCTGGTCGGACGGCAGGCCCGATGGATCGCACCATCGACAATCAGATCAGCCGTCTCCGCCGCAAAATCGAGC
CGGATGTACTTAGGCCCAGTGTCATCAAAACGGTGCGGAACGGCGGATACTGTCTGGCTGCCGATGTCGAGGATGCGCCG
TGA

Upstream 100 bases:

>100_bases
GCACAGATTTGTATCCATCTGTAGCAAGGGACTGACCTGATACAAACGGCTACAATTCTGCCCATGAAACAGAATGCAAC
GATGATCTAGGAAGGACGCC

Downstream 100 bases:

>100_bases
TGCGCCGTGCGATGAGATCTCTGAGCGGCCAATTGATCCTGCTTGTGGTCGCGGCACTTGTCGTGGCCCAGGTGATCAGC
CTGTTCCTGTTCGCCGACGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MGPPPHILIVDDHAQIRESVARFLEKNGMRTTVARDAVEMDAKLATGHFDLLVLDVMMPGEDGLSVCRRLAPEGDLPIIM
LTALGEETDRIVGLEIGADDYLAKPFNPRELLARIKSVLRRSNRDEPVAGSLAGRKVSFAHWILDTDRQVLIDESTTETP
LTTSEFKLLAVLLERARMVLSRDQLLDLTAGRTAGPMDRTIDNQISRLRRKIEPDVLRPSVIKTVRNGGYCLAADVEDAP

Sequences:

>Translated_240_residues
MGPPPHILIVDDHAQIRESVARFLEKNGMRTTVARDAVEMDAKLATGHFDLLVLDVMMPGEDGLSVCRRLAPEGDLPIIM
LTALGEETDRIVGLEIGADDYLAKPFNPRELLARIKSVLRRSNRDEPVAGSLAGRKVSFAHWILDTDRQVLIDESTTETP
LTTSEFKLLAVLLERARMVLSRDQLLDLTAGRTAGPMDRTIDNQISRLRRKIEPDVLRPSVIKTVRNGGYCLAADVEDAP
>Mature_239_residues
GPPPHILIVDDHAQIRESVARFLEKNGMRTTVARDAVEMDAKLATGHFDLLVLDVMMPGEDGLSVCRRLAPEGDLPIIML
TALGEETDRIVGLEIGADDYLAKPFNPRELLARIKSVLRRSNRDEPVAGSLAGRKVSFAHWILDTDRQVLIDESTTETPL
TTSEFKLLAVLLERARMVLSRDQLLDLTAGRTAGPMDRTIDNQISRLRRKIEPDVLRPSVIKTVRNGGYCLAADVEDAP

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=47.4358974358974, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=35.3191489361702, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=40.0862068965517, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=35.7142857142857, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=40.4347826086956, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=36.5217391304348, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=35.3448275862069, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=35.0877192982456, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=36.8888888888889, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790552, Length=239, Percent_Identity=33.8912133891213, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=32.0175438596491, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=30.7359307359307, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=29.1304347826087, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790299, Length=130, Percent_Identity=30, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26585; Mature: 26454

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPPPHILIVDDHAQIRESVARFLEKNGMRTTVARDAVEMDAKLATGHFDLLVLDVMMPG
CCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
EDGLSVCRRLAPEGDLPIIMLTALGEETDRIVGLEIGADDYLAKPFNPRELLARIKSVLR
CHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCCHHCCCCCHHHHHHHHHHHHH
RSNRDEPVAGSLAGRKVSFAHWILDTDRQVLIDESTTETPLTTSEFKLLAVLLERARMVL
HCCCCCCCCCCCCCCEEEHHHEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
SRDQLLDLTAGRTAGPMDRTIDNQISRLRRKIEPDVLRPSVIKTVRNGGYCLAADVEDAP
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure 
GPPPHILIVDDHAQIRESVARFLEKNGMRTTVARDAVEMDAKLATGHFDLLVLDVMMPG
CCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
EDGLSVCRRLAPEGDLPIIMLTALGEETDRIVGLEIGADDYLAKPFNPRELLARIKSVLR
CHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCCHHCCCCCHHHHHHHHHHHHH
RSNRDEPVAGSLAGRKVSFAHWILDTDRQVLIDESTTETPLTTSEFKLLAVLLERARMVL
HCCCCCCCCCCCCCCEEEHHHEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
SRDQLLDLTAGRTAGPMDRTIDNQISRLRRKIEPDVLRPSVIKTVRNGGYCLAADVEDAP
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]