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The map label for this gene is adh-6 [H]

Identifier: 15899092

GI number: 15899092

Start: 2133042

End: 2134058

Strand: Reverse

Name: adh-6 [H]

Synonym: SSO2334

Alternate gene names: 15899092

Gene position: 2134058-2133042 (Counterclockwise)

Preceding gene: 15899093

Following gene: 15899081

Centisome position: 71.32

GC content: 38.84

Gene sequence:

>1017_bases
TTGCAGATAAGACTAACTCTTATGAAAGCCCTAGTTTTCGACAAGAGTGGTTTAGAAAATCTCAAGGTAAAAGAAGTTCA
AGAACCACAATTAGGTCCGCATGACGTTTTGATAAGAGTAGTTAAATCTGGTTTAAACCCCATAGATTACTTTGTTATTA
ACGCAATTCCAGTTACTCCAATGCCCCATATCCCCGGAGCAGAACTAGCTGGAGTAGTTGAAAAAGTGGGGGATCATGTA
AAAGGATTAAATAAGGGGGATAAGGTAGTAGTGTACAATAGAGTATTTGATGGTACTTGTGATTTATGCCTATCTGGAAG
GGAAATGTTATGTAGAAACGGCGGGATAATGAGTGTCATAACTAACGGCGGATGGTCAGAATACTTTTCGGTTCCAGATA
AAAACATTTTCAAAATTCCGGAAAGTATGAGTTGGGATGTCGCCGCTAGCTTACCCGTAGCAGCTCTAACTTCATACCAT
TCTCTAAAAGAATTAGAAGTAGGCCCTAACGATATTATAGTAATATTTGGTGCGAGTGGCAATACCGGACTTTTCGCAGT
ACAACTAGCTAAAAAGTTCGGGGCAACAGTTATAGCGGTTTCAAGAAAGAACTGGTTAAAAGAGTTTGGTGCAGATTACA
TAGTAGGATATGATGATGTAGTGCAAAAGGTTAAAGAAATAACCAATGGGAAAATGGCCGATGTAGTAATAAACTCCTTA
GGCTCCTCAATGTGGGAAAATAGCTTACAGGTTCTAGGTTTAGATGGTCAATTGGCGTTCTTTGGAACTTTAACTGGAAG
TGAAGTGAAGGTAAATCTAAGCTCCCTATACGGAAGGCATATAAAGGTAGTTGGAACCACGGGGGGATCTAGGAAGGAAC
TAATGGAATTAATAAATCTGTGTAAGGATTGCAAGGTAAAAGTCCACAAAACTTACAAGTTAGATGAAGGTGTAGAGGCG
GTAAAAGAGATTATGAACGAAAATAGAGAAGGGAGAATAATGCTACAAGTATCATAA

Upstream 100 bases:

>100_bases
GATTTCGTAAGCCTAGCGTATGAGTATATTAGCTTTAAGAATAAGGCTAAGATAGGAATAAGAGGATAGTAGTTACCTAA
AGTTAAGTAACCGATTTATA

Downstream 100 bases:

>100_bases
AATTGAGGTTGGCTCTCTTAAGAAGTCTAATATATATCTTGTAATATCACTTATCTCTTTAGGAGGATCAATATCCTTGA
AATGTCTTTGTGTGAGAGAA

Product: zinc-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MQIRLTLMKALVFDKSGLENLKVKEVQEPQLGPHDVLIRVVKSGLNPIDYFVINAIPVTPMPHIPGAELAGVVEKVGDHV
KGLNKGDKVVVYNRVFDGTCDLCLSGREMLCRNGGIMSVITNGGWSEYFSVPDKNIFKIPESMSWDVAASLPVAALTSYH
SLKELEVGPNDIIVIFGASGNTGLFAVQLAKKFGATVIAVSRKNWLKEFGADYIVGYDDVVQKVKEITNGKMADVVINSL
GSSMWENSLQVLGLDGQLAFFGTLTGSEVKVNLSSLYGRHIKVVGTTGGSRKELMELINLCKDCKVKVHKTYKLDEGVEA
VKEIMNENREGRIMLQVS

Sequences:

>Translated_338_residues
MQIRLTLMKALVFDKSGLENLKVKEVQEPQLGPHDVLIRVVKSGLNPIDYFVINAIPVTPMPHIPGAELAGVVEKVGDHV
KGLNKGDKVVVYNRVFDGTCDLCLSGREMLCRNGGIMSVITNGGWSEYFSVPDKNIFKIPESMSWDVAASLPVAALTSYH
SLKELEVGPNDIIVIFGASGNTGLFAVQLAKKFGATVIAVSRKNWLKEFGADYIVGYDDVVQKVKEITNGKMADVVINSL
GSSMWENSLQVLGLDGQLAFFGTLTGSEVKVNLSSLYGRHIKVVGTTGGSRKELMELINLCKDCKVKVHKTYKLDEGVEA
VKEIMNENREGRIMLQVS
>Mature_338_residues
MQIRLTLMKALVFDKSGLENLKVKEVQEPQLGPHDVLIRVVKSGLNPIDYFVINAIPVTPMPHIPGAELAGVVEKVGDHV
KGLNKGDKVVVYNRVFDGTCDLCLSGREMLCRNGGIMSVITNGGWSEYFSVPDKNIFKIPESMSWDVAASLPVAALTSYH
SLKELEVGPNDIIVIFGASGNTGLFAVQLAKKFGATVIAVSRKNWLKEFGADYIVGYDDVVQKVKEITNGKMADVVINSL
GSSMWENSLQVLGLDGQLAFFGTLTGSEVKVNLSSLYGRHIKVVGTTGGSRKELMELINLCKDCKVKVHKTYKLDEGVEA
VKEIMNENREGRIMLQVS

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=294, Percent_Identity=25.5102040816327, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI13236495, Length=294, Percent_Identity=25.5102040816327, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI22538446, Length=279, Percent_Identity=28.673835125448, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI22538444, Length=279, Percent_Identity=28.673835125448, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI194239676, Length=202, Percent_Identity=28.2178217821782, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI18379349, Length=253, Percent_Identity=30.0395256916996, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI24308257, Length=372, Percent_Identity=27.1505376344086, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1790485, Length=344, Percent_Identity=27.906976744186, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790045, Length=202, Percent_Identity=31.6831683168317, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788073, Length=263, Percent_Identity=28.1368821292776, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787863, Length=218, Percent_Identity=28.8990825688073, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788407, Length=268, Percent_Identity=28.3582089552239, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082125, Length=290, Percent_Identity=25.8620689655172, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788075, Length=280, Percent_Identity=27.8571428571429, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI226510992, Length=291, Percent_Identity=24.0549828178694, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786825, Length=288, Percent_Identity=26.7361111111111, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082401, Length=344, Percent_Identity=24.1279069767442, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081918, Length=306, Percent_Identity=27.1241830065359, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786518, Length=305, Percent_Identity=24.2622950819672, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71988145, Length=335, Percent_Identity=28.6567164179104, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17562584, Length=304, Percent_Identity=29.2763157894737, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562582, Length=335, Percent_Identity=27.7611940298507, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17507255, Length=351, Percent_Identity=26.7806267806268, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562876, Length=243, Percent_Identity=26.7489711934156, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562878, Length=335, Percent_Identity=23.8805970149254, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323961, Length=306, Percent_Identity=25.1633986928105, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6323729, Length=293, Percent_Identity=25.5972696245734, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319621, Length=347, Percent_Identity=25.3602305475504, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319520, Length=350, Percent_Identity=24, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=313, Percent_Identity=23.961661341853, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320033, Length=275, Percent_Identity=26.5454545454545, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323099, Length=344, Percent_Identity=24.1279069767442, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319949, Length=335, Percent_Identity=26.2686567164179, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322619, Length=337, Percent_Identity=24.6290801186944, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17737897, Length=292, Percent_Identity=26.3698630136986, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17137530, Length=294, Percent_Identity=25.1700680272109, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36931; Mature: 36931

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIRLTLMKALVFDKSGLENLKVKEVQEPQLGPHDVLIRVVKSGLNPIDYFVINAIPVTP
CEEHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHEEEEEEECCCC
MPHIPGAELAGVVEKVGDHVKGLNKGDKVVVYNRVFDGTCDLCLSGREMLCRNGGIMSVI
CCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHCCCHHHHHCCCEEEEE
TNGGWSEYFSVPDKNIFKIPESMSWDVAASLPVAALTSYHSLKELEVGPNDIIVIFGASG
ECCCCHHHCCCCCCCEEECCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCC
NTGLFAVQLAKKFGATVIAVSRKNWLKEFGADYIVGYDDVVQKVKEITNGKMADVVINSL
CCCEEEEEEHHHHCCEEEEECHHHHHHHHCCCEEECHHHHHHHHHHHHCCHHHHHHHHHH
GSSMWENSLQVLGLDGQLAFFGTLTGSEVKVNLSSLYGRHIKVVGTTGGSRKELMELINL
HHHHHHCCEEEEECCCCEEEEEEECCCEEEEEHHHHCCCEEEEEECCCCCHHHHHHHHHH
CKDCKVKVHKTYKLDEGVEAVKEIMNENREGRIMLQVS
HHHCCEEEEEEEECHHHHHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MQIRLTLMKALVFDKSGLENLKVKEVQEPQLGPHDVLIRVVKSGLNPIDYFVINAIPVTP
CEEHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHEEEEEEECCCC
MPHIPGAELAGVVEKVGDHVKGLNKGDKVVVYNRVFDGTCDLCLSGREMLCRNGGIMSVI
CCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHCCCHHHHHCCCEEEEE
TNGGWSEYFSVPDKNIFKIPESMSWDVAASLPVAALTSYHSLKELEVGPNDIIVIFGASG
ECCCCHHHCCCCCCCEEECCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCC
NTGLFAVQLAKKFGATVIAVSRKNWLKEFGADYIVGYDDVVQKVKEITNGKMADVVINSL
CCCEEEEEEHHHHCCEEEEECHHHHHHHHCCCEEECHHHHHHHHHHHHCCHHHHHHHHHH
GSSMWENSLQVLGLDGQLAFFGTLTGSEVKVNLSSLYGRHIKVVGTTGGSRKELMELINL
HHHHHHCCEEEEECCCCEEEEEEECCCEEEEEHHHHCCCEEEEEECCCCCHHHHHHHHHH
CKDCKVKVHKTYKLDEGVEAVKEIMNENREGRIMLQVS
HHHCCEEEEEEEECHHHHHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA