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The map label for this gene is bphC [H]

Identifier: 15898844

GI number: 15898844

Start: 1873107

End: 1874057

Strand: Reverse

Name: bphC [H]

Synonym: SSO2054

Alternate gene names: 15898844

Gene position: 1874057-1873107 (Counterclockwise)

Preceding gene: 15898845

Following gene: 15898843

Centisome position: 62.63

GC content: 39.85

Gene sequence:

>951_bases
TTGATGATCAACACTTTACGTACATCTCATGTGTGTATAAGAGTTAGCGATTTGGATAAGGCGAGATACTTCTACTCAGA
ACTCTTAGGATTTGTGGAGACAGAAAAGGATGGCGATTATATTTATTTGAGAGGGATTGAGGAAGGTCAGCATCATAGCT
TAATACTAAAAAAGGCCAACTCGGCTGGTTTATCGTATATAGGCTTTAGGGTAAGTAAAGGAGAGGAATTAGATAAGGCC
AGAGAAGAATTGGAAAACCTAGGTCATAAGGTTAGGAAATTTAGGGAAAAGGGTATTAATGAAGCTCTATTATTTGAATC
CCCCGAAGGAATCCCAATACTTCTATACTATGACATGGAGTATGTAGGCGATTTAAGATTAGCATTTCATAGGCATAGGG
GAGTGAGTCCAGTCAGGTTAGCCCACGTAAATTATATGGTTAAGGACTTGGAGAGAGAATTGGAGTTCTTTAAGAGATTC
ATGGGTTACTATGAGACTGAGAGGTTCTTGGATAAGGATGGGAATTTGGCAGTAGTGTGGTTAACTAGAAGAGGGGATTC
ACACGAAATAGCAATAGCGAAGTCAAGTAAAAACGTTCCGGGATTTCACCATGAGACGTATTACGTTCATGATGTAAAAG
ATGTCATTAAAGCCCCAGATATTCTAGCCTCAGTGGGATTGTGGGATAGTATAGAAAGGGGTCCCGGTAGACATGGTGTA
ACTGAGGGTTATTATATTTATTTGAGAGATTTTGATAAAAATAGAATTGAGTTCTTCACCAACGATTACGTGGTTCTGGA
TCCGGATAAGTGGAAACCAATAGTTTGGACCTATGATCAATTAAGGTATAGAAGTGATTTTTGGGGAAGGCCGATTCCTC
AATCTTGGTTAACTGAATGGGTTGCCGTGGAGGATATTTCCACGGGTCAATTAAAGGGGTGGTCTGGATGA

Upstream 100 bases:

>100_bases
TCACCCTTAGTCTATTACAATAGAAATTATTGGAAGTTATGTAGATAACCTTAAATCAGTTTAATAGTGAATTAATTTAT
CTTTTTGCACGTGATAGTGT

Downstream 100 bases:

>100_bases
TAAGAAGGGGAACAGATTACATAAAAAGTATAAAGGAAAACCCACCAGTAGTTTACTATGAAGGAGAAGTAGTAAAGGAT
GTTACAGAACATTCAGCATT

Product: catechol 2,3-dioxygenase (metapyrocatechase)

Products: NA

Alternate protein names: Mn(II)-dependent 2,3-dihydroxybiphenyl 1,2-dioxygenase; Mn(II)-dependent 23OHBP oxygenase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MMINTLRTSHVCIRVSDLDKARYFYSELLGFVETEKDGDYIYLRGIEEGQHHSLILKKANSAGLSYIGFRVSKGEELDKA
REELENLGHKVRKFREKGINEALLFESPEGIPILLYYDMEYVGDLRLAFHRHRGVSPVRLAHVNYMVKDLERELEFFKRF
MGYYETERFLDKDGNLAVVWLTRRGDSHEIAIAKSSKNVPGFHHETYYVHDVKDVIKAPDILASVGLWDSIERGPGRHGV
TEGYYIYLRDFDKNRIEFFTNDYVVLDPDKWKPIVWTYDQLRYRSDFWGRPIPQSWLTEWVAVEDISTGQLKGWSG

Sequences:

>Translated_316_residues
MMINTLRTSHVCIRVSDLDKARYFYSELLGFVETEKDGDYIYLRGIEEGQHHSLILKKANSAGLSYIGFRVSKGEELDKA
REELENLGHKVRKFREKGINEALLFESPEGIPILLYYDMEYVGDLRLAFHRHRGVSPVRLAHVNYMVKDLERELEFFKRF
MGYYETERFLDKDGNLAVVWLTRRGDSHEIAIAKSSKNVPGFHHETYYVHDVKDVIKAPDILASVGLWDSIERGPGRHGV
TEGYYIYLRDFDKNRIEFFTNDYVVLDPDKWKPIVWTYDQLRYRSDFWGRPIPQSWLTEWVAVEDISTGQLKGWSG
>Mature_316_residues
MMINTLRTSHVCIRVSDLDKARYFYSELLGFVETEKDGDYIYLRGIEEGQHHSLILKKANSAGLSYIGFRVSKGEELDKA
REELENLGHKVRKFREKGINEALLFESPEGIPILLYYDMEYVGDLRLAFHRHRGVSPVRLAHVNYMVKDLERELEFFKRF
MGYYETERFLDKDGNLAVVWLTRRGDSHEIAIAKSSKNVPGFHHETYYVHDVKDVIKAPDILASVGLWDSIERGPGRHGV
TEGYYIYLRDFDKNRIEFFTNDYVVLDPDKWKPIVWTYDQLRYRSDFWGRPIPQSWLTEWVAVEDISTGQLKGWSG

Specific function: Catalyzes the meta-cleavage of the hydroxylated biphenyl ring. The enzyme can oxidize a wide range of substrates, and the substrate preference order is 2,3-dihydroxybiphenyl > 3- methylcatechol > catechol > 4-methylcatechol > 4-chlorocatechol [H]

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: =1.13.11.39 [H]

Molecular weight: Translated: 37031; Mature: 37031

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00934 GLYOXALASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMINTLRTSHVCIRVSDLDKARYFYSELLGFVETEKDGDYIYLRGIEEGQHHSLILKKAN
CEECCEECCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECC
SAGLSYIGFRVSKGEELDKAREELENLGHKVRKFREKGINEALLFESPEGIPILLYYDME
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCH
YVGDLRLAFHRHRGVSPVRLAHVNYMVKDLERELEFFKRFMGYYETERFLDKDGNLAVVW
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LTRRGDSHEIAIAKSSKNVPGFHHETYYVHDVKDVIKAPDILASVGLWDSIERGPGRHGV
EEECCCCCEEEEEECCCCCCCCCCCEEEEECHHHHHCCCHHHHHCCCHHHHHCCCCCCCC
TEGYYIYLRDFDKNRIEFFTNDYVVLDPDKWKPIVWTYDQLRYRSDFWGRPIPQSWLTEW
CCCEEEEEEECCCCCEEEEECCEEEECCCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHH
VAVEDISTGQLKGWSG
HEEECCCCCCCCCCCC
>Mature Secondary Structure
MMINTLRTSHVCIRVSDLDKARYFYSELLGFVETEKDGDYIYLRGIEEGQHHSLILKKAN
CEECCEECCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECC
SAGLSYIGFRVSKGEELDKAREELENLGHKVRKFREKGINEALLFESPEGIPILLYYDME
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCH
YVGDLRLAFHRHRGVSPVRLAHVNYMVKDLERELEFFKRFMGYYETERFLDKDGNLAVVW
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LTRRGDSHEIAIAKSSKNVPGFHHETYYVHDVKDVIKAPDILASVGLWDSIERGPGRHGV
EEECCCCCEEEEEECCCCCCCCCCCEEEEECHHHHHCCCHHHHHCCCHHHHHCCCCCCCC
TEGYYIYLRDFDKNRIEFFTNDYVVLDPDKWKPIVWTYDQLRYRSDFWGRPIPQSWLTEW
CCCEEEEEEECCCCCEEEEECCEEEECCCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHH
VAVEDISTGQLKGWSG
HEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12672826 [H]