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The map label for this gene is rfbC-2 [H]

Identifier: 15898723

GI number: 15898723

Start: 1745029

End: 1745559

Strand: Reverse

Name: rfbC-2 [H]

Synonym: SSO1923

Alternate gene names: 15898723

Gene position: 1745559-1745029 (Counterclockwise)

Preceding gene: 15898725

Following gene: 15898720

Centisome position: 58.34

GC content: 36.53

Gene sequence:

>531_bases
ATGCCGTTTGAATTTGAAAACTTAGGAATGGGTATTGTCCTCATAAAGCCGAAAGTCTTCCCAGATAAAAGAGGCTTCTT
TCTTGAAGTATTTAAATCTGAAGACTTCACTAAAGCAGAAATTCCTAATATCGTACAAACTAATATGTCATTCTCTTTTA
AAGGAGTAGTTAGAGGTCTACACTATCAGATAACTCCCAAGGAACAAGGTAAGTTAGTATTTGTTCCTAAAGGTAAAATA
TTGGATGTTGCTTTAGACCTAAGAAAATCATCCCCTACTTTCGGGAAATACGTTAAAGTTGAGCTTAACGATGAGAACCA
CTACATACTATGGATACCTCCGGGTTTTGCCCATGGATTTCAAGCATTAGAAGATTCAATAGTAGTCTACTTCCTAACCC
ATAACGAATACTCTAAATCTGACGAGAGATGCGTAAATTACTCTTATGTAGACTGGCCAATAAAGGAATTTATTATAAGC
GATAAGGACTCACAGTGCCCGCCCTTAGAAAAGGCAGACGTCTTTAATTAA

Upstream 100 bases:

>100_bases
ACCTGTATAGGTTAAGGGGATGAAAGTCCTCCTTCCTTAAGGGATGGATAGCCCGTAATCATTCAGATAGCTCTTTATAG
ATCGTGTATAATATAATCAT

Downstream 100 bases:

>100_bases
GCTACTCTATAGCAATACATACTGTTGGCTCTGCATTTTAGAGTGTTCTTATGCAGTTATCTTATTCTATATTTGCTTTA
AAATTATTAGCATAATACAA

Product: dTDP-4-dehydrorhamnose 3,5 epimerase (rfbC-2)

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MPFEFENLGMGIVLIKPKVFPDKRGFFLEVFKSEDFTKAEIPNIVQTNMSFSFKGVVRGLHYQITPKEQGKLVFVPKGKI
LDVALDLRKSSPTFGKYVKVELNDENHYILWIPPGFAHGFQALEDSIVVYFLTHNEYSKSDERCVNYSYVDWPIKEFIIS
DKDSQCPPLEKADVFN

Sequences:

>Translated_176_residues
MPFEFENLGMGIVLIKPKVFPDKRGFFLEVFKSEDFTKAEIPNIVQTNMSFSFKGVVRGLHYQITPKEQGKLVFVPKGKI
LDVALDLRKSSPTFGKYVKVELNDENHYILWIPPGFAHGFQALEDSIVVYFLTHNEYSKSDERCVNYSYVDWPIKEFIIS
DKDSQCPPLEKADVFN
>Mature_175_residues
PFEFENLGMGIVLIKPKVFPDKRGFFLEVFKSEDFTKAEIPNIVQTNMSFSFKGVVRGLHYQITPKEQGKLVFVPKGKIL
DVALDLRKSSPTFGKYVKVELNDENHYILWIPPGFAHGFQALEDSIVVYFLTHNEYSKSDERCVNYSYVDWPIKEFIISD
KDSQCPPLEKADVFN

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=167, Percent_Identity=38.3233532934132, Blast_Score=106, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17550412, Length=164, Percent_Identity=42.6829268292683, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20308; Mature: 20176

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFEFENLGMGIVLIKPKVFPDKRGFFLEVFKSEDFTKAEIPNIVQTNMSFSFKGVVRGL
CCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCHHCCCCEEECCCCEEEEHEECCE
HYQITPKEQGKLVFVPKGKILDVALDLRKSSPTFGKYVKVELNDENHYILWIPPGFAHGF
EEEECCCCCCCEEEEECCCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCHHHHH
QALEDSIVVYFLTHNEYSKSDERCVNYSYVDWPIKEFIISDKDSQCPPLEKADVFN
HHCCCCEEEEEEECCCCCCCCCCEECCEEECCCHHHEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PFEFENLGMGIVLIKPKVFPDKRGFFLEVFKSEDFTKAEIPNIVQTNMSFSFKGVVRGL
CCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCHHCCCCEEECCCCEEEEHEECCE
HYQITPKEQGKLVFVPKGKILDVALDLRKSSPTFGKYVKVELNDENHYILWIPPGFAHGF
EEEECCCCCCCEEEEECCCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCHHHHH
QALEDSIVVYFLTHNEYSKSDERCVNYSYVDWPIKEFIISDKDSQCPPLEKADVFN
HHCCCCEEEEEEECCCCCCCCCCEECCEEECCCHHHEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8170390; 8157605; 12384590; 12704152 [H]