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The map label for this gene is thpS [H]

Identifier: 15898683

GI number: 15898683

Start: 1701327

End: 1702997

Strand: Reverse

Name: thpS [H]

Synonym: SSO1886

Alternate gene names: 15898683

Gene position: 1702997-1701327 (Counterclockwise)

Preceding gene: 15898684

Following gene: 15898680

Centisome position: 56.91

GC content: 35.25

Gene sequence:

>1671_bases
GTGCTAAAGCATATAGTGTTAGTCCTTCTTTTGCTCTTATTAACACCGTTAGTTGCCATTTCATTTCCAACTGGAGTAGT
AGCTTATAATGGTCCTATATGTACAAATGAAGTACTAGGTTATGCAAATATATCATCGCTGTTGGCTTATAACACTTCTG
CATCACAGCTTGGAGTTCCGCCTTATGGCGCTTCGCTTCAATTAAACGTTATGTTAGAAGTAAATACTAGCGGTGGAGAA
TACTATTTCTGGTTACAAAATGTAGCTGATTTCATTACAAATGAGAGTAAGGTATTCTTTGGCGACAATATTTGGAACTC
GACTACTCCCTTTGCTGGAATAAACAATATAGTTGGCAAAGGTGAAATATACTCTACTTCAGACTTTTTCTCTCATTCCT
CATACTACGCTTATGGGACTTATTATATTAAATATAATTTCCCCTTTTCGTTCTACCTTATAATAAATGAGAGCTATGAT
ACTCAAGGAGTATATGTTAGTTTCGGTTATGTTATTCTTCAAAACGGAAATATAAGTCCACCTAACCCAATATTTTACGA
TACGGTCTTCATTCCAATTCAAAATTTATCATTTGCTTCAATTATAATAGCTAATCAAACCACCCCCAGCGCGAATTTTG
GTATTGTTACATATCTGGGAAATTATTTAGATGCTGAGTTAGTATGGGGAGGATTTGGGAATGGTGAAAGCACAACTTTC
TTAAACATGTCTTCTTACTTAGCATTACTCTATATGAAAAGTGGCGAATGGGTTCCATTTTCACAAGTATACAATTACGG
AAGTGATACCGCAGAATCCACTAATAATTTGCAAGTTTTGATAGGTAAAAACGGTGATGCTTACGTTACAATAGGCAGAC
AGAACCCTGGTCTATTGACTACAAAATTTAACCCTTCATATCCAAGTTTCCTATACTTAAACATTAGTAGCAAAATACCA
TTTCTACTAAATAAAAGCCTTTCACATGCATTCTCCGGCTACGTTACCACCCAAATTAAATTAGGATTCTTTAAGAACTA
TTCAATTAACTCATCGTCATTTGCAGTGCTTAATGGAAACTATCCCAGCCTAATAGAACCTAACGTTAGTTGGTTTAAGG
TTTTGAATATTATTCCCAATTATACATATTACTATCTGGTGAAAGTAAACTCACAAATTCCAGTTATTGCCAATGTGAAT
GGTAAACAAATAACTTTGAACAGTACAGATTGGTTTGCTCAAGGCACTCAAATCAGCATACTCAATTATACATATTACAA
CGGTAGCAATGAGAGGTACATAATATCATCAATTTTACCGTCATCGTCATTCAACGTTAGTCTACCTTTAAACATAACCT
TAAGCACAATAAAACAATATCGGGTTTTAGTAGACTCCAATCTACCCGTATATTTAAATGGTGAAAGAGTGAATGGAAGT
GTATGGATTAACGCGGGTTCCTCCATTCAATTAAGTGCTAACGTTCCCTTTTACGAAAAGGGCATATTTACGGGGACTTA
TAACGTAACACCAGGGAGCATTATAACGGTAAATGGGCCAATAGTTGAGACCTTAATATTATCCATCAATACTGAACTAA
TGGGTATAGTGGCAGTAATAGTAATAGCAGTAGTAGCAATTGCCATATTGGTATTGAGGCGAAGAAGATGA

Upstream 100 bases:

>100_bases
TTAGTGTTATACAATATCGTTTTAATGAGACAAATTGAACAAATCAACAAAGTACAATTTAGGAAAACGTTTTTATTTTT
AAAAATTCATTTTCCCTTTC

Downstream 100 bases:

>100_bases
TAAAAATCATAACGTAATTTTTTTGAATCTAATTCTTACATGGATATAGGCTAAAGATAGACCGATAAGCATTGAGACAA
TTATAAGCAATGATGTATTA

Product: thermopsin precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MLKHIVLVLLLLLLTPLVAISFPTGVVAYNGPICTNEVLGYANISSLLAYNTSASQLGVPPYGASLQLNVMLEVNTSGGE
YYFWLQNVADFITNESKVFFGDNIWNSTTPFAGINNIVGKGEIYSTSDFFSHSSYYAYGTYYIKYNFPFSFYLIINESYD
TQGVYVSFGYVILQNGNISPPNPIFYDTVFIPIQNLSFASIIIANQTTPSANFGIVTYLGNYLDAELVWGGFGNGESTTF
LNMSSYLALLYMKSGEWVPFSQVYNYGSDTAESTNNLQVLIGKNGDAYVTIGRQNPGLLTTKFNPSYPSFLYLNISSKIP
FLLNKSLSHAFSGYVTTQIKLGFFKNYSINSSSFAVLNGNYPSLIEPNVSWFKVLNIIPNYTYYYLVKVNSQIPVIANVN
GKQITLNSTDWFAQGTQISILNYTYYNGSNERYIISSILPSSSFNVSLPLNITLSTIKQYRVLVDSNLPVYLNGERVNGS
VWINAGSSIQLSANVPFYEKGIFTGTYNVTPGSIITVNGPIVETLILSINTELMGIVAVIVIAVVAIAILVLRRRR

Sequences:

>Translated_556_residues
MLKHIVLVLLLLLLTPLVAISFPTGVVAYNGPICTNEVLGYANISSLLAYNTSASQLGVPPYGASLQLNVMLEVNTSGGE
YYFWLQNVADFITNESKVFFGDNIWNSTTPFAGINNIVGKGEIYSTSDFFSHSSYYAYGTYYIKYNFPFSFYLIINESYD
TQGVYVSFGYVILQNGNISPPNPIFYDTVFIPIQNLSFASIIIANQTTPSANFGIVTYLGNYLDAELVWGGFGNGESTTF
LNMSSYLALLYMKSGEWVPFSQVYNYGSDTAESTNNLQVLIGKNGDAYVTIGRQNPGLLTTKFNPSYPSFLYLNISSKIP
FLLNKSLSHAFSGYVTTQIKLGFFKNYSINSSSFAVLNGNYPSLIEPNVSWFKVLNIIPNYTYYYLVKVNSQIPVIANVN
GKQITLNSTDWFAQGTQISILNYTYYNGSNERYIISSILPSSSFNVSLPLNITLSTIKQYRVLVDSNLPVYLNGERVNGS
VWINAGSSIQLSANVPFYEKGIFTGTYNVTPGSIITVNGPIVETLILSINTELMGIVAVIVIAVVAIAILVLRRRR
>Mature_556_residues
MLKHIVLVLLLLLLTPLVAISFPTGVVAYNGPICTNEVLGYANISSLLAYNTSASQLGVPPYGASLQLNVMLEVNTSGGE
YYFWLQNVADFITNESKVFFGDNIWNSTTPFAGINNIVGKGEIYSTSDFFSHSSYYAYGTYYIKYNFPFSFYLIINESYD
TQGVYVSFGYVILQNGNISPPNPIFYDTVFIPIQNLSFASIIIANQTTPSANFGIVTYLGNYLDAELVWGGFGNGESTTF
LNMSSYLALLYMKSGEWVPFSQVYNYGSDTAESTNNLQVLIGKNGDAYVTIGRQNPGLLTTKFNPSYPSFLYLNISSKIP
FLLNKSLSHAFSGYVTTQIKLGFFKNYSINSSSFAVLNGNYPSLIEPNVSWFKVLNIIPNYTYYYLVKVNSQIPVIANVN
GKQITLNSTDWFAQGTQISILNYTYYNGSNERYIISSILPSSSFNVSLPLNITLSTIKQYRVLVDSNLPVYLNGERVNGS
VWINAGSSIQLSANVPFYEKGIFTGTYNVTPGSIITVNGPIVETLILSINTELMGIVAVIVIAVVAIAILVLRRRR

Specific function: May represent a new class of acid proteases. It digests proteins and peptides in acidic solution [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=May be linked to cells by covalent linkages through some side chains [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A5 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007981 [H]

Pfam domain/function: PF05317 Thermopsin [H]

EC number: =3.4.23.42 [H]

Molecular weight: Translated: 61462; Mature: 61462

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKHIVLVLLLLLLTPLVAISFPTGVVAYNGPICTNEVLGYANISSLLAYNTSASQLGVP
CHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCHHHHCCCCCHHHHEEECCCCHHCCCC
PYGASLQLNVMLEVNTSGGEYYFWLQNVADFITNESKVFFGDNIWNSTTPFAGINNIVGK
CCCCCEEEEEEEEEECCCCEEEEEHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCC
GEIYSTSDFFSHSSYYAYGTYYIKYNFPFSFYLIINESYDTQGVYVSFGYVILQNGNISP
CEEEECHHHCCCCCEEEEEEEEEEEECCEEEEEEEECCCCCCEEEEEEEEEEEECCCCCC
PNPIFYDTVFIPIQNLSFASIIIANQTTPSANFGIVTYLGNYLDAELVWGGFGNGESTTF
CCCEEEEEEEEEECCCCEEEEEEEECCCCCCCCEEHEECCCCCCEEEEEECCCCCCCEEE
LNMSSYLALLYMKSGEWVPFSQVYNYGSDTAESTNNLQVLIGKNGDAYVTIGRQNPGLLT
EEHHHEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEE
TKFNPSYPSFLYLNISSKIPFLLNKSLSHAFSGYVTTQIKLGFFKNYSINSSSFAVLNGN
EEECCCCCCEEEEEECCCCCCEECCCHHHHHCCEEEEEEEEEEEECCCCCCCCEEEEECC
YPSLIEPNVSWFKVLNIIPNYTYYYLVKVNSQIPVIANVNGKQITLNSTDWFAQGTQISI
CCCEECCCCHHEEHHHHCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCCEECCCEEEE
LNYTYYNGSNERYIISSILPSSSFNVSLPLNITLSTIKQYRVLVDSNLPVYLNGERVNGS
EEEEEECCCCCEEEEEEECCCCCCEEEEEEEEEEEHHEEEEEEEECCCCEEEECCEECEE
VWINAGSSIQLSANVPFYEKGIFTGTYNVTPGSIITVNGPIVETLILSINTELMGIVAVI
EEEECCCEEEEEECCCEECCCEEEEEEECCCCCEEEECCCCEEEEEEECCHHHHHHHHHH
VIAVVAIAILVLRRRR
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKHIVLVLLLLLLTPLVAISFPTGVVAYNGPICTNEVLGYANISSLLAYNTSASQLGVP
CHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCHHHHCCCCCHHHHEEECCCCHHCCCC
PYGASLQLNVMLEVNTSGGEYYFWLQNVADFITNESKVFFGDNIWNSTTPFAGINNIVGK
CCCCCEEEEEEEEEECCCCEEEEEHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCC
GEIYSTSDFFSHSSYYAYGTYYIKYNFPFSFYLIINESYDTQGVYVSFGYVILQNGNISP
CEEEECHHHCCCCCEEEEEEEEEEEECCEEEEEEEECCCCCCEEEEEEEEEEEECCCCCC
PNPIFYDTVFIPIQNLSFASIIIANQTTPSANFGIVTYLGNYLDAELVWGGFGNGESTTF
CCCEEEEEEEEEECCCCEEEEEEEECCCCCCCCEEHEECCCCCCEEEEEECCCCCCCEEE
LNMSSYLALLYMKSGEWVPFSQVYNYGSDTAESTNNLQVLIGKNGDAYVTIGRQNPGLLT
EEHHHEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEE
TKFNPSYPSFLYLNISSKIPFLLNKSLSHAFSGYVTTQIKLGFFKNYSINSSSFAVLNGN
EEECCCCCCEEEEEECCCCCCEECCCHHHHHCCEEEEEEEEEEEECCCCCCCCEEEEECC
YPSLIEPNVSWFKVLNIIPNYTYYYLVKVNSQIPVIANVNGKQITLNSTDWFAQGTQISI
CCCEECCCCHHEEHHHHCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCCEECCCEEEE
LNYTYYNGSNERYIISSILPSSSFNVSLPLNITLSTIKQYRVLVDSNLPVYLNGERVNGS
EEEEEECCCCCEEEEEEECCCCCCEEEEEEEEEEEHHEEEEEEEECCCCEEEECCEECEE
VWINAGSSIQLSANVPFYEKGIFTGTYNVTPGSIITVNGPIVETLILSINTELMGIVAVI
EEEECCCEEEEEECCCEECCCEEEEEEECCCCCEEEECCCCEEEEEEECCHHHHHHHHHH
VIAVVAIAILVLRRRR
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2104843 [H]