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The map label for this gene is htpX-1

Identifier: 15898652

GI number: 15898652

Start: 1676422

End: 1677357

Strand: Reverse

Name: htpX-1

Synonym: SSO1859

Alternate gene names: 15898652

Gene position: 1677357-1676422 (Counterclockwise)

Preceding gene: 15898653

Following gene: 15898651

Centisome position: 56.06

GC content: 37.82

Gene sequence:

>936_bases
ATGGATGTAAGACAAAGGTTGATATCGAGCATGGTTATCTCGTTAGGTCTGACCATTATATCGGAGGGTATAGTATTGAT
TGGAATAGCTTCTCTACTTCATATATCTTTATTTTTTATATTTCCAGCTCTCGTAATTTTCTGGCTATTTCAATGGATTA
TATCTCCTTATGTAGTGGGAAGAGGTGGCTATGAAGTTTCTCCAAATGACCCACAGTACGGCTGGCTTTACAATTTAGTT
AGGAGAATAGCTGAGGAGTCCAAAATTAAGCCCCCTAGAGTTTTTGTAATCGACGCACCTTATCCTAATGCATTTGCTTA
CGGTAATAGATTAGGCGGGATGAGAGTTGGAATAACTCTACCCCTCTTGAACATTCTGGACGTTGATGAGTTAACCGCAG
TTATAGCTCATGAAGTAGGACACATAAAGCACAGGGACGTTGAGATAGGTATGACAATAGGTCTTATTCCTACAGTGTTA
GGATATATAAGTACACTACTGATGAATTTCGGATATTTGGCATTATTCCTTGCAGCAGATGAAATTGAACTATTATTCGC
CATAGCGGCTTTAGCAATAGGATTTGTCATATTCGTAGTAACTTTCATCTTGCAAATTTTCGTCTTATGGTTTAATAGGC
TGAGAGAATCCTATGCAGATTATAATTCTTTTCTAGTATTAGGAGAGGGGTCGAAGGCTTTAGCTACTGCGTTAGCTAAG
ATTGAAATTTACATGCAAAACATTAGGATTGACCCATTCACTGGAATTATAGTGACAGCTCCACCAGTTAAGGTGGAAGA
GAAAGATCCTCACTTGCTAGTCGAACAGTGGTTGAGAACTAAGGTTAGTGCATTTAAGGACATTTTATCAACTCATCCCT
ATCCAGCTAGAAGAGCTCAAATGATTTATCGATTAATATATGGTAGTAATATATAG

Upstream 100 bases:

>100_bases
TAGTTTTACTCGTAATAATCTTGGGGATTATGGCAATTATTAGTGGAATCTTAAGTGATATTGCAAAAGGTTTTTATTAA
AAGATATACAAGGTTTTATC

Downstream 100 bases:

>100_bases
TCTACATGCTTCTAAATATAATATAATTTCTCTATACGGAATCTTTATAAAATGATTAATGAAGTGTATAATATGGGATT
CAATGGGATAAAATTCGATA

Product: heat shock protein (htpX-1)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MDVRQRLISSMVISLGLTIISEGIVLIGIASLLHISLFFIFPALVIFWLFQWIISPYVVGRGGYEVSPNDPQYGWLYNLV
RRIAEESKIKPPRVFVIDAPYPNAFAYGNRLGGMRVGITLPLLNILDVDELTAVIAHEVGHIKHRDVEIGMTIGLIPTVL
GYISTLLMNFGYLALFLAADEIELLFAIAALAIGFVIFVVTFILQIFVLWFNRLRESYADYNSFLVLGEGSKALATALAK
IEIYMQNIRIDPFTGIIVTAPPVKVEEKDPHLLVEQWLRTKVSAFKDILSTHPYPARRAQMIYRLIYGSNI

Sequences:

>Translated_311_residues
MDVRQRLISSMVISLGLTIISEGIVLIGIASLLHISLFFIFPALVIFWLFQWIISPYVVGRGGYEVSPNDPQYGWLYNLV
RRIAEESKIKPPRVFVIDAPYPNAFAYGNRLGGMRVGITLPLLNILDVDELTAVIAHEVGHIKHRDVEIGMTIGLIPTVL
GYISTLLMNFGYLALFLAADEIELLFAIAALAIGFVIFVVTFILQIFVLWFNRLRESYADYNSFLVLGEGSKALATALAK
IEIYMQNIRIDPFTGIIVTAPPVKVEEKDPHLLVEQWLRTKVSAFKDILSTHPYPARRAQMIYRLIYGSNI
>Mature_311_residues
MDVRQRLISSMVISLGLTIISEGIVLIGIASLLHISLFFIFPALVIFWLFQWIISPYVVGRGGYEVSPNDPQYGWLYNLV
RRIAEESKIKPPRVFVIDAPYPNAFAYGNRLGGMRVGITLPLLNILDVDELTAVIAHEVGHIKHRDVEIGMTIGLIPTVL
GYISTLLMNFGYLALFLAADEIELLFAIAALAIGFVIFVVTFILQIFVLWFNRLRESYADYNSFLVLGEGSKALATALAK
IEIYMQNIRIDPFTGIIVTAPPVKVEEKDPHLLVEQWLRTKVSAFKDILSTHPYPARRAQMIYRLIYGSNI

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family

Homologues:

Organism=Escherichia coli, GI1788133, Length=233, Percent_Identity=29.6137339055794, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HTPX1_SULSO (Q97X95)

Other databases:

- EMBL:   AE006641
- PIR:   H90348
- RefSeq:   NP_343257.1
- ProteinModelPortal:   Q97X95
- SMR:   Q97X95
- GeneID:   1453374
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO1859
- NMPDR:   fig|273057.1.peg.1680
- HOGENOM:   HBG739460
- OMA:   LERKENK
- ProtClustDB:   CLSK803163
- BioCyc:   SSOL273057:SSO1859-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_00188
- InterPro:   IPR022919
- InterPro:   IPR001915

Pfam domain/function: PF01435 Peptidase_M48

EC number: 3.4.24.- [C]

Molecular weight: Translated: 34986; Mature: 34986

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 138-138

Signals:

None

Transmembrane regions:

HASH(0xd8cfc64)-; HASH(0xf562c08)-; HASH(0xe7ed6fc)-; HASH(0xed4990c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRQRLISSMVISLGLTIISEGIVLIGIASLLHISLFFIFPALVIFWLFQWIISPYVVG
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEC
RGGYEVSPNDPQYGWLYNLVRRIAEESKIKPPRVFVIDAPYPNAFAYGNRLGGMRVGITL
CCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCCCCEEEEHHH
PLLNILDVDELTAVIAHEVGHIKHRDVEIGMTIGLIPTVLGYISTLLMNFGYLALFLAAD
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIELLFAIAALAIGFVIFVVTFILQIFVLWFNRLRESYADYNSFLVLGEGSKALATALAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
IEIYMQNIRIDPFTGIIVTAPPVKVEEKDPHLLVEQWLRTKVSAFKDILSTHPYPARRAQ
HHHHHHHEECCCCCCEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MIYRLIYGSNI
HHHHHHHCCCH
>Mature Secondary Structure
MDVRQRLISSMVISLGLTIISEGIVLIGIASLLHISLFFIFPALVIFWLFQWIISPYVVG
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEC
RGGYEVSPNDPQYGWLYNLVRRIAEESKIKPPRVFVIDAPYPNAFAYGNRLGGMRVGITL
CCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCCCCEEEEHHH
PLLNILDVDELTAVIAHEVGHIKHRDVEIGMTIGLIPTVLGYISTLLMNFGYLALFLAAD
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIELLFAIAALAIGFVIFVVTFILQIFVLWFNRLRESYADYNSFLVLGEGSKALATALAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
IEIYMQNIRIDPFTGIIVTAPPVKVEEKDPHLLVEQWLRTKVSAFKDILSTHPYPARRAQ
HHHHHHHEECCCCCCEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MIYRLIYGSNI
HHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11427726