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The map label for this gene is paaX [H]

Identifier: 15898156

GI number: 15898156

Start: 1145079

End: 1145879

Strand: Direct

Name: paaX [H]

Synonym: SSO1315

Alternate gene names: 15898156

Gene position: 1145079-1145879 (Clockwise)

Preceding gene: 15898155

Following gene: 15898157

Centisome position: 38.27

GC content: 34.96

Gene sequence:

>801_bases
ATGAAGATACAATCGTTATTCTTTACATTGTATGGAGATTACATAAAAGATGCGGGAGGAACGATAAGTTCCAAAAGCTT
GATTATTATTCTTAAAGAATTTGGTTTTTCAGAAGGTGCGATTAGAGCTGGTTTACACAGAATGAAGAAAGCCGGTTTAA
TAGTCTCTGAAAGGGGAAAAGATAAGAAAATAAGATATAAATTGTCTGAAAAAGGGCTGTTGAGATTACTAGAAGGAACT
AGGAGAGTCTATGAAAAGACTAGAAGAAGATGGGATGGCAAATGGAGGATAGTAGTGTATAACATTCCAGAAAATAACAG
GGAGGTAAGAGATAGATTGAGGAGAGAGCTAAAATGGTTAGGATTTGGAATGCTAGCTCAGTCAACATGGATATCACCAA
ATCCTATTGAAGATACGTTAAGGAAATTTATCAATGATCTCTACAACTCGACCAATAGCGTGAAGGTAGACATTTTTGTG
GCAGATTATTTAGATCAACCTAATCATTTGGTAGAAAGATGTTGGAATTTAGTTGAAGTCGAACAAGCTTACAAGTCTTT
TTTAGAAGAATGGTCTCCAATGCTTAAAAAGGTCAACTCCATGAAAAGTAATGAAGCGTTTGTAACTAGGATAGAATTAG
TCCATGAATATAGAAAATTTCTAAATATAGACCCTGATTTACCAGAAGATTTATTGCCCCAGAATTGGATAGGTTATAAG
GCATATGACCTCTTCATGAAACTGAGAGAGGAATTAACACCAAAGGCAAATGAGTTCTTTTACAAGGTGTATGAGCCATA
A

Upstream 100 bases:

>100_bases
TAAATTTAGACTGGGTGAAGTAAAATAAAATTTTTACAGCTATCATAGTACTTATAATACCCAAGAAAATTTTTTAGTAT
TTATTTAGAGGTTATTATTA

Downstream 100 bases:

>100_bases
AACTTTATGCTATCATTTAAAAAAGTTTAGTATATACTAATTTTCTTAAATTAAACAATTTTACTTCTTATATCTTATTT
AGCAATAGTATTAAATTAAA

Product: repressor in ring oxydation complex/ phenylacetic acid degradation pathway related protein (paaX)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MKIQSLFFTLYGDYIKDAGGTISSKSLIIILKEFGFSEGAIRAGLHRMKKAGLIVSERGKDKKIRYKLSEKGLLRLLEGT
RRVYEKTRRRWDGKWRIVVYNIPENNREVRDRLRRELKWLGFGMLAQSTWISPNPIEDTLRKFINDLYNSTNSVKVDIFV
ADYLDQPNHLVERCWNLVEVEQAYKSFLEEWSPMLKKVNSMKSNEAFVTRIELVHEYRKFLNIDPDLPEDLLPQNWIGYK
AYDLFMKLREELTPKANEFFYKVYEP

Sequences:

>Translated_266_residues
MKIQSLFFTLYGDYIKDAGGTISSKSLIIILKEFGFSEGAIRAGLHRMKKAGLIVSERGKDKKIRYKLSEKGLLRLLEGT
RRVYEKTRRRWDGKWRIVVYNIPENNREVRDRLRRELKWLGFGMLAQSTWISPNPIEDTLRKFINDLYNSTNSVKVDIFV
ADYLDQPNHLVERCWNLVEVEQAYKSFLEEWSPMLKKVNSMKSNEAFVTRIELVHEYRKFLNIDPDLPEDLLPQNWIGYK
AYDLFMKLREELTPKANEFFYKVYEP
>Mature_266_residues
MKIQSLFFTLYGDYIKDAGGTISSKSLIIILKEFGFSEGAIRAGLHRMKKAGLIVSERGKDKKIRYKLSEKGLLRLLEGT
RRVYEKTRRRWDGKWRIVVYNIPENNREVRDRLRRELKWLGFGMLAQSTWISPNPIEDTLRKFINDLYNSTNSVKVDIFV
ADYLDQPNHLVERCWNLVEVEQAYKSFLEEWSPMLKKVNSMKSNEAFVTRIELVHEYRKFLNIDPDLPEDLLPQNWIGYK
AYDLFMKLREELTPKANEFFYKVYEP

Specific function: Negative regulator of the paaZ and paaABCDEFGHIJK catabolic operons. Binds the consensus sequence 5'- WWTRTGATTCGYGWT-3'. Binding of paaX is specifically inhibited by phenylacetyl-coenzyme A [H]

COG id: COG3327

COG function: function code K; Phenylacetic acid-responsive transcriptional repressor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787666, Length=262, Percent_Identity=29.7709923664122, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012906
- InterPro:   IPR013225
- InterPro:   IPR011965 [H]

Pfam domain/function: PF07848 PaaX; PF08223 PaaX_C [H]

EC number: NA

Molecular weight: Translated: 31577; Mature: 31577

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIQSLFFTLYGDYIKDAGGTISSKSLIIILKEFGFSEGAIRAGLHRMKKAGLIVSERGK
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCC
DKKIRYKLSEKGLLRLLEGTRRVYEKTRRRWDGKWRIVVYNIPENNREVRDRLRRELKWL
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
GFGMLAQSTWISPNPIEDTLRKFINDLYNSTNSVKVDIFVADYLDQPNHLVERCWNLVEV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
EQAYKSFLEEWSPMLKKVNSMKSNEAFVTRIELVHEYRKFLNIDPDLPEDLLPQNWIGYK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHH
AYDLFMKLREELTPKANEFFYKVYEP
HHHHHHHHHHHHCCCHHHHEEEECCC
>Mature Secondary Structure
MKIQSLFFTLYGDYIKDAGGTISSKSLIIILKEFGFSEGAIRAGLHRMKKAGLIVSERGK
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCC
DKKIRYKLSEKGLLRLLEGTRRVYEKTRRRWDGKWRIVVYNIPENNREVRDRLRRELKWL
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
GFGMLAQSTWISPNPIEDTLRKFINDLYNSTNSVKVDIFVADYLDQPNHLVERCWNLVEV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
EQAYKSFLEEWSPMLKKVNSMKSNEAFVTRIELVHEYRKFLNIDPDLPEDLLPQNWIGYK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHH
AYDLFMKLREELTPKANEFFYKVYEP
HHHHHHHHHHHHCCCHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]