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The map label for this gene is nuoH [H]

Identifier: 15893153

GI number: 15893153

Start: 1134472

End: 1135491

Strand: Reverse

Name: nuoH [H]

Synonym: RC1230

Alternate gene names: 15893153

Gene position: 1135491-1134472 (Counterclockwise)

Preceding gene: 15893154

Following gene: 15893152

Centisome position: 89.5

GC content: 35.98

Gene sequence:

>1020_bases
ATGCTAGAACTCTTTTTTGAATATATTTTTCCGTTAATTATCATCGCTCTAAAGGTAGTTGCAATTACTATCCCTTTAAT
ATTGTGCGTTGCGTATTTAACATATGCAGAGCGTCGTGTTATTGGATTAATGCAGCTTCGACGAGGACCTAACGTTGTCG
GTCCGTTTGGATTACTTCAGCCTATTGCCGATGCGGTTAAGCTCTTATTCAAAGAGCCGATCATTCCAACCAATTCCGAT
AAAATATTATTTATTTTAGCACCGATGATAACTTTTATATTAAGTTTAATCGGTTGGGCAGTTATACCCTTTGCAAAGGG
CGTAGTTCTGGCAGATATTAATGTAGGTGTTTTATATATTCTTGCTATTTCTTCTTTAAGTGTTTACGGCATTATTATTG
CTGGTTGGGCTAGTAACTCAAAATATGCTTTTTTAGGAGCTATACGTTCCTCTGCCCAAATGATTTCTTATGAAATGTCG
ATGGGGCTGGTTATTATTACCGTGCTACTTACTAACGGTACTCTCAATTTAAGTGGGATCATTGAAGCACAAAGAACAAT
GCCGTGGTGGATTGATTTAATGCTACTACCTATGGGTGTCGTGTTTTTTATCTCGGTGCTTGCCGAAACAAATAGATTAC
CTTTTGATTTACCTGAAGCAGAATCGGAGTTAGTTGCTGGCTATAATGTTGAATATTCCTCTATGGGATTTGCTTTATTT
TTTCTAGGTGAATATGCTAATATGATATTAGTTAGTGCAATGACTACGACTTTCTTTTTAGGAGGTTACTTGCCGCCCTT
TAATATATCGTGGTTAGATTGTATTCCGGGGTTCTTTTGGTTTGTATTTAAGGTCGGATTCTTATTATTTTGTTTTTTAT
GGATTAGAGCGACCTTACCAAGATATCGCTATGATCAATTAATGCGACTTGGTTGGAAAGTATTTTTACCTCTAACTTTA
TTTTGGGTAGTGTTAGTATCAAGTGTGCTTGTTTATACAGATAATTTACCGAGTATTTAG

Upstream 100 bases:

>100_bases
GAGGTGGCATGATGAAAAATATGCTATTCTCACCCCGTATGTCATTCCTGCAAAAGCTGGATTCTCACTTTTGCGGGAAT
GATATAATAAGAGTACAACC

Downstream 100 bases:

>100_bases
GTGTTATTATCATTGTTGCTTGATCGGTTTACCCGTCATTGCGAGGAAATTACGAAGTAATTGACGAAGCAATCTCAGGA
TATTTGATGAGATTGCCACG

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MLELFFEYIFPLIIIALKVVAITIPLILCVAYLTYAERRVIGLMQLRRGPNVVGPFGLLQPIADAVKLLFKEPIIPTNSD
KILFILAPMITFILSLIGWAVIPFAKGVVLADINVGVLYILAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEMS
MGLVIITVLLTNGTLNLSGIIEAQRTMPWWIDLMLLPMGVVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALF
FLGEYANMILVSAMTTTFFLGGYLPPFNISWLDCIPGFFWFVFKVGFLLFCFLWIRATLPRYRYDQLMRLGWKVFLPLTL
FWVVLVSSVLVYTDNLPSI

Sequences:

>Translated_339_residues
MLELFFEYIFPLIIIALKVVAITIPLILCVAYLTYAERRVIGLMQLRRGPNVVGPFGLLQPIADAVKLLFKEPIIPTNSD
KILFILAPMITFILSLIGWAVIPFAKGVVLADINVGVLYILAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEMS
MGLVIITVLLTNGTLNLSGIIEAQRTMPWWIDLMLLPMGVVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALF
FLGEYANMILVSAMTTTFFLGGYLPPFNISWLDCIPGFFWFVFKVGFLLFCFLWIRATLPRYRYDQLMRLGWKVFLPLTL
FWVVLVSSVLVYTDNLPSI
>Mature_339_residues
MLELFFEYIFPLIIIALKVVAITIPLILCVAYLTYAERRVIGLMQLRRGPNVVGPFGLLQPIADAVKLLFKEPIIPTNSD
KILFILAPMITFILSLIGWAVIPFAKGVVLADINVGVLYILAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEMS
MGLVIITVLLTNGTLNLSGIIEAQRTMPWWIDLMLLPMGVVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALF
FLGEYANMILVSAMTTTFFLGGYLPPFNISWLDCIPGFFWFVFKVGFLLFCFLWIRATLPRYRYDQLMRLGWKVFLPLTL
FWVVLVSSVLVYTDNLPSI

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=294, Percent_Identity=48.6394557823129, Blast_Score=270, Evalue=2e-72,
Organism=Escherichia coli, GI1788618, Length=319, Percent_Identity=42.9467084639498, Blast_Score=273, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 38061; Mature: 38061

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELFFEYIFPLIIIALKVVAITIPLILCVAYLTYAERRVIGLMQLRRGPNVVGPFGLLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
PIADAVKLLFKEPIIPTNSDKILFILAPMITFILSLIGWAVIPFAKGVVLADINVGVLYI
HHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHH
LAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEMSMGLVIITVLLTNGTLNLSGI
HHHHHHHEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IEAQRTMPWWIDLMLLPMGVVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHH
FLGEYANMILVSAMTTTFFLGGYLPPFNISWLDCIPGFFWFVFKVGFLLFCFLWIRATLP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RYRYDQLMRLGWKVFLPLTLFWVVLVSSVLVYTDNLPSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLELFFEYIFPLIIIALKVVAITIPLILCVAYLTYAERRVIGLMQLRRGPNVVGPFGLLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
PIADAVKLLFKEPIIPTNSDKILFILAPMITFILSLIGWAVIPFAKGVVLADINVGVLYI
HHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHH
LAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEMSMGLVIITVLLTNGTLNLSGI
HHHHHHHEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IEAQRTMPWWIDLMLLPMGVVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHH
FLGEYANMILVSAMTTTFFLGGYLPPFNISWLDCIPGFFWFVFKVGFLLFCFLWIRATLP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RYRYDQLMRLGWKVFLPLTLFWVVLVSSVLVYTDNLPSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA