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The map label for this gene is mhpA [C]

Identifier: 15889866

GI number: 15889866

Start: 2588806

End: 2590077

Strand: Reverse

Name: mhpA [C]

Synonym: Atu2610

Alternate gene names: 15889866

Gene position: 2590077-2588806 (Counterclockwise)

Preceding gene: 159185289

Following gene: 159185287

Centisome position: 91.15

GC content: 60.53

Gene sequence:

>1272_bases
ATGGGGGCGAGGGTGATGGAAGACGCGAAAGCCGGGCATGAAAAGGACGGCAGAGCCGTTCAGAATATCCACACCTGTGT
TGCCGTGGCCGGTGGCGGACCGGCAGGCATGATGCTCGGCCTGCTGCTCGCCCGCAGCGGTATCGATGTTGTTGTCGTCG
AGAAACACGGGGATTTTCTGCGCGATTTTCGTGGCGACACCATCCATCCTTCCACGCTTGAATTGATGGAACAGCTCGGT
TTCATCGACGAGTTCTTAAGCCTTCCGCATACACGCGCGCCGCGGCTGAACGCGGTTATCGGTGGTGAGCGCGTCACGAT
TGCGGATTTTTCCCGCCTGCCGGTCCGGCATCGGTTCATCGCCTTCATGCCGCAATGGGATTTTCTCAATTTCATCGTCG
GCAAGGCAGGGCAATATGAAAATTTCCGCCTGCTGATGAATGCGCCGGTCACCGGCCTCATCGAACGGGACGGGCGCGTC
GGCGGCCTCACCGTCGAAACGCCGGAAGGGGTCATCGAGATCGCTGCCGATCTGGTGGTCGGTGCAGATGGCCGCAACTC
CATCGTCCGTGAGGCGGCAGGGCTCGAGGTCCAGCGCTTCGGCATCCCGACCGAAGTGCTGTGGCTGCGCCTTTCGAAAC
AGCCTGACGATCCGACCGAAACCATGGGGCATGCCGGCTCGCGACAGGGTTTCGTGATGATCAACCGGGGTGACTACTGG
CAATGCGGTTATGTGGTGCGCAAGGGATTTTTCGCGGACATAAAGCTGGAGGGGCTTGAGGCCTTTCGGTACAGGGTCGC
GGAAATCTGCCCTTTCCCACGCGAAAGGCTCGATGAGCTCAAGAGCTGGGACGATGTGCATCTCCTTACCGTTCGTATCG
ACCGCCTGAAGCGCTGGTGGAAACCCGGTCTGATCTGCATCGGCGATGCGGCCCATGCCATGTCGCCCGTCGGCGGCGTC
GGCGTCAATCTGGCCATTCAGGACGCGGTTGCCGCCGCCAATATATTGGTGCCGGTGCTGGTGTCCGGCCGGGCCATTCG
TGATGATGACCTCGCCGCAATCGAAAAGCGGCGGTCCTTCCCGACCAAGGCCACGCAGTTTCTGCAGCGGATGATGCGTA
TCGGTCGCAAGAAAGGGCAAGAGGAAAGAGCGGAAAAGCCCAAAGGCCCGCCTGCCTTCGTGCGGGCGATTATTCGATTT
CCGCTTCTTTCCCATCTGACTGGCCGGCTGGTGGGGCTGGGTTTCCGTCGGGAAAAGATTGAGACGCCGTGA

Upstream 100 bases:

>100_bases
TTCGAAATGCTGTTCCGTTTCGACGCACAGGGCTGGCCGCAGCCGAAGAATGCAAGCCCTCCGGCGGCTGAAACAAGATA
AAGAGATTTAACGGGACCGG

Downstream 100 bases:

>100_bases
GAGCCATCAGGACGGGCGGGCGATCTCCTGCGCATATTTCAACCCGATAACGGCTGATCCGATCAGCCCCGGCTCGATGC
GGCAGATGGCGGGCACGACC

Product: hypothetical protein

Products: H2O; 3-(2,3-dihydroxyphenyl)propionate; NAD [C]

Alternate protein names: None

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MGARVMEDAKAGHEKDGRAVQNIHTCVAVAGGGPAGMMLGLLLARSGIDVVVVEKHGDFLRDFRGDTIHPSTLELMEQLG
FIDEFLSLPHTRAPRLNAVIGGERVTIADFSRLPVRHRFIAFMPQWDFLNFIVGKAGQYENFRLLMNAPVTGLIERDGRV
GGLTVETPEGVIEIAADLVVGADGRNSIVREAAGLEVQRFGIPTEVLWLRLSKQPDDPTETMGHAGSRQGFVMINRGDYW
QCGYVVRKGFFADIKLEGLEAFRYRVAEICPFPRERLDELKSWDDVHLLTVRIDRLKRWWKPGLICIGDAAHAMSPVGGV
GVNLAIQDAVAAANILVPVLVSGRAIRDDDLAAIEKRRSFPTKATQFLQRMMRIGRKKGQEERAEKPKGPPAFVRAIIRF
PLLSHLTGRLVGLGFRREKIETP

Sequences:

>Translated_423_residues
MGARVMEDAKAGHEKDGRAVQNIHTCVAVAGGGPAGMMLGLLLARSGIDVVVVEKHGDFLRDFRGDTIHPSTLELMEQLG
FIDEFLSLPHTRAPRLNAVIGGERVTIADFSRLPVRHRFIAFMPQWDFLNFIVGKAGQYENFRLLMNAPVTGLIERDGRV
GGLTVETPEGVIEIAADLVVGADGRNSIVREAAGLEVQRFGIPTEVLWLRLSKQPDDPTETMGHAGSRQGFVMINRGDYW
QCGYVVRKGFFADIKLEGLEAFRYRVAEICPFPRERLDELKSWDDVHLLTVRIDRLKRWWKPGLICIGDAAHAMSPVGGV
GVNLAIQDAVAAANILVPVLVSGRAIRDDDLAAIEKRRSFPTKATQFLQRMMRIGRKKGQEERAEKPKGPPAFVRAIIRF
PLLSHLTGRLVGLGFRREKIETP
>Mature_422_residues
GARVMEDAKAGHEKDGRAVQNIHTCVAVAGGGPAGMMLGLLLARSGIDVVVVEKHGDFLRDFRGDTIHPSTLELMEQLGF
IDEFLSLPHTRAPRLNAVIGGERVTIADFSRLPVRHRFIAFMPQWDFLNFIVGKAGQYENFRLLMNAPVTGLIERDGRVG
GLTVETPEGVIEIAADLVVGADGRNSIVREAAGLEVQRFGIPTEVLWLRLSKQPDDPTETMGHAGSRQGFVMINRGDYWQ
CGYVVRKGFFADIKLEGLEAFRYRVAEICPFPRERLDELKSWDDVHLLTVRIDRLKRWWKPGLICIGDAAHAMSPVGGVG
VNLAIQDAVAAANILVPVLVSGRAIRDDDLAAIEKRRSFPTKATQFLQRMMRIGRKKGQEERAEKPKGPPAFVRAIIRFP
LLSHLTGRLVGLGFRREKIETP

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786543, Length=380, Percent_Identity=26.0526315789474, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.14.13.- [C]

Molecular weight: Translated: 46909; Mature: 46778

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGARVMEDAKAGHEKDGRAVQNIHTCVAVAGGGPAGMMLGLLLARSGIDVVVVEKHGDFL
CCCCCCHHHHCCCCCCCHHHHHHEEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCHHH
RDFRGDTIHPSTLELMEQLGFIDEFLSLPHTRAPRLNAVIGGERVTIADFSRLPVRHRFI
HHCCCCCCCCHHHHHHHHHCHHHHHHCCCCCCCCCCEEEECCCEEEEECHHCCCHHHHHE
AFMPQWDFLNFIVGKAGQYENFRLLMNAPVTGLIERDGRVGGLTVETPEGVIEIAADLVV
EECCCHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCCEEEECCCHHHHHHHHHEE
GADGRNSIVREAAGLEVQRFGIPTEVLWLRLSKQPDDPTETMGHAGSRQGFVMINRGDYW
CCCCCHHHHHHHCCCEEEECCCCHHHEEEEECCCCCCHHHHHCCCCCCCCEEEEECCCCE
QCGYVVRKGFFADIKLEGLEAFRYRVAEICPFPRERLDELKSWDDVHLLTVRIDRLKRWW
EHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEEHHHHHHHC
KPGLICIGDAAHAMSPVGGVGVNLAIQDAVAAANILVPVLVSGRAIRDDDLAAIEKRRSF
CCCEEEECCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
PTKATQFLQRMMRIGRKKGQEERAEKPKGPPAFVRAIIRFPLLSHLTGRLVGLGFRREKI
CHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
ETP
CCC
>Mature Secondary Structure 
GARVMEDAKAGHEKDGRAVQNIHTCVAVAGGGPAGMMLGLLLARSGIDVVVVEKHGDFL
CCCCCHHHHCCCCCCCHHHHHHEEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCHHH
RDFRGDTIHPSTLELMEQLGFIDEFLSLPHTRAPRLNAVIGGERVTIADFSRLPVRHRFI
HHCCCCCCCCHHHHHHHHHCHHHHHHCCCCCCCCCCEEEECCCEEEEECHHCCCHHHHHE
AFMPQWDFLNFIVGKAGQYENFRLLMNAPVTGLIERDGRVGGLTVETPEGVIEIAADLVV
EECCCHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCCEEEECCCHHHHHHHHHEE
GADGRNSIVREAAGLEVQRFGIPTEVLWLRLSKQPDDPTETMGHAGSRQGFVMINRGDYW
CCCCCHHHHHHHCCCEEEECCCCHHHEEEEECCCCCCHHHHHCCCCCCCCEEEEECCCCE
QCGYVVRKGFFADIKLEGLEAFRYRVAEICPFPRERLDELKSWDDVHLLTVRIDRLKRWW
EHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEEHHHHHHHC
KPGLICIGDAAHAMSPVGGVGVNLAIQDAVAAANILVPVLVSGRAIRDDDLAAIEKRRSF
CCCEEEECCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
PTKATQFLQRMMRIGRKKGQEERAEKPKGPPAFVRAIIRFPLLSHLTGRLVGLGFRREKI
CHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
ETP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-(3-hydroxyphenyl)propionate; NADH; O2 [C]

Specific reaction: 3-(3-hydroxyphenyl)propionate + NADH + O2 = H2O + 3-(2,3-dihydroxyphenyl)propionate + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA