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The map label for this gene is kamA [H]

Identifier: 15889814

GI number: 15889814

Start: 2528949

End: 2530040

Strand: Direct

Name: kamA [H]

Synonym: Atu2555

Alternate gene names: 15889814

Gene position: 2528949-2530040 (Clockwise)

Preceding gene: 15889813

Following gene: 159185265

Centisome position: 89.0

GC content: 59.71

Gene sequence:

>1092_bases
GTGGGCGCCCGTCGCGGAATATGGACGATGACAAGGTTTGAAACCATCAAGACACCGGAAGCGCTGCTCGAAGCGGGGCT
GATCGAAGCAGAGGCGCTTGAGGGTCTGCGCGCGGTGACGCAGCGTTATGCGCTCGCCATCACGCCAGCGGTTACCGGGC
TGATGGATAGTCACGATCCGCAGGATCCGATCGCCCGGCAATTTGTGCCTGACCTCGCCGAACTCGTCCATCTTCCCGAA
GAACGCGACGATCCGATCGGCGACGACGCCCATAGCCCCGTCCACGGCATCGTTCACCGTTATCCCGACCGCGTGCTTTT
GAAGGCGGTGCATGTTTGCCCGGTCTATTGCCGTTTCTGTTTCCGCCGCGAAATGGTCGGCCCGCAGGGCAACGGGATGA
TGAGCCCGGAAGAGCTGGACGCTGCATTCGCCTATATAAAAGAGAACCCGGCTATCTGGGAGGTCATCCTCACCGGTGGC
GATCCTCTGGTGCTCTCGCCACGACGATTGTCAGACCTGATGAAACGGCTAAGGGACATACCGCACGTCAAGATCGTCCG
TTTCCATACCCGCGTGCCGGTTGTCGATCCCGACCGCATTGACGCGCCACTGATCGAAGCATTGAAGGCGAGCGGCAAAA
CCACCTATGTCGCCCTGCATGCCAATCACGCCCGCGAACTCGGCGATGCTGCCAGAAACGCCTGCGCACGGTTGATCGAT
GCCGGCATAGCCATGGTCAGCCAGACCGTTCTTTTGAAGGGCATCAACGATGATCCGGCGGTTCTGGCCGACCTGATGCG
CAGCTTCGTCGAAAACCGTATCAAGCCCTATTATCTGCACCATCCCGATCTTGCCCCGGGCACAAGCCATTTCCGGTTGA
CGATCGAAGAGGGGCAGCGAATCGTTTCCGCCTTGCGCGGGCATGTCTCCGGTCTTTGCCAGCCGACCTATGTTCTCGAC
ATCCCCGGCGGTCACGGCAAGGCCATGATCGGCCGAAATGCGGCCGAAAAAACCCGCGATGGCTGTTACTCCGTCTCCGA
CTTCAACGGAAACGATCATATTTACCCGCCGGCGACATCCGGCAGCTATTAA

Upstream 100 bases:

>100_bases
TGGCCGCACTTGCGATCATGCCCCCGGCAAGCGGCATAGCGCTCGGTTTCGACCGGCTGGTGATGTTGGCAACCGGCGCA
CCCCGCATCGATCTCGTCAT

Downstream 100 bases:

>100_bases
AAAAAAGCATAAAAAGCTCGCCACGCCGGGCTTTTCGCGGCGGCTTCCCACGAAAACAAAAATTTCACATTTCCGCCCCT
CTCCTGTCATCATAAAGAAA

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGARRGIWTMTRFETIKTPEALLEAGLIEAEALEGLRAVTQRYALAITPAVTGLMDSHDPQDPIARQFVPDLAELVHLPE
ERDDPIGDDAHSPVHGIVHRYPDRVLLKAVHVCPVYCRFCFRREMVGPQGNGMMSPEELDAAFAYIKENPAIWEVILTGG
DPLVLSPRRLSDLMKRLRDIPHVKIVRFHTRVPVVDPDRIDAPLIEALKASGKTTYVALHANHARELGDAARNACARLID
AGIAMVSQTVLLKGINDDPAVLADLMRSFVENRIKPYYLHHPDLAPGTSHFRLTIEEGQRIVSALRGHVSGLCQPTYVLD
IPGGHGKAMIGRNAAEKTRDGCYSVSDFNGNDHIYPPATSGSY

Sequences:

>Translated_363_residues
MGARRGIWTMTRFETIKTPEALLEAGLIEAEALEGLRAVTQRYALAITPAVTGLMDSHDPQDPIARQFVPDLAELVHLPE
ERDDPIGDDAHSPVHGIVHRYPDRVLLKAVHVCPVYCRFCFRREMVGPQGNGMMSPEELDAAFAYIKENPAIWEVILTGG
DPLVLSPRRLSDLMKRLRDIPHVKIVRFHTRVPVVDPDRIDAPLIEALKASGKTTYVALHANHARELGDAARNACARLID
AGIAMVSQTVLLKGINDDPAVLADLMRSFVENRIKPYYLHHPDLAPGTSHFRLTIEEGQRIVSALRGHVSGLCQPTYVLD
IPGGHGKAMIGRNAAEKTRDGCYSVSDFNGNDHIYPPATSGSY
>Mature_362_residues
GARRGIWTMTRFETIKTPEALLEAGLIEAEALEGLRAVTQRYALAITPAVTGLMDSHDPQDPIARQFVPDLAELVHLPEE
RDDPIGDDAHSPVHGIVHRYPDRVLLKAVHVCPVYCRFCFRREMVGPQGNGMMSPEELDAAFAYIKENPAIWEVILTGGD
PLVLSPRRLSDLMKRLRDIPHVKIVRFHTRVPVVDPDRIDAPLIEALKASGKTTYVALHANHARELGDAARNACARLIDA
GIAMVSQTVLLKGINDDPAVLADLMRSFVENRIKPYYLHHPDLAPGTSHFRLTIEEGQRIVSALRGHVSGLCQPTYVLDI
PGGHGKAMIGRNAAEKTRDGCYSVSDFNGNDHIYPPATSGSY

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=325, Percent_Identity=32.9230769230769, Blast_Score=184, Evalue=9e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 40017; Mature: 39886

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGARRGIWTMTRFETIKTPEALLEAGLIEAEALEGLRAVTQRYALAITPAVTGLMDSHDP
CCCCCCCEEHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHEEHHHHHHHHCCCCC
QDPIARQFVPDLAELVHLPEERDDPIGDDAHSPVHGIVHRYPDRVLLKAVHVCPVYCRFC
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FRREMVGPQGNGMMSPEELDAAFAYIKENPAIWEVILTGGDPLVLSPRRLSDLMKRLRDI
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEECHHHHHHHHHHHHCC
PHVKIVRFHTRVPVVDPDRIDAPLIEALKASGKTTYVALHANHARELGDAARNACARLID
CCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
AGIAMVSQTVLLKGINDDPAVLADLMRSFVENRIKPYYLHHPDLAPGTSHFRLTIEEGQR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEHHHHHH
IVSALRGHVSGLCQPTYVLDIPGGHGKAMIGRNAAEKTRDGCYSVSDFNGNDHIYPPATS
HHHHHHHHHHCCCCCCEEEECCCCCCCEECCCCHHHHHHCCCEEECCCCCCCCCCCCCCC
GSY
CCC
>Mature Secondary Structure 
GARRGIWTMTRFETIKTPEALLEAGLIEAEALEGLRAVTQRYALAITPAVTGLMDSHDP
CCCCCCEEHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHEEHHHHHHHHCCCCC
QDPIARQFVPDLAELVHLPEERDDPIGDDAHSPVHGIVHRYPDRVLLKAVHVCPVYCRFC
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FRREMVGPQGNGMMSPEELDAAFAYIKENPAIWEVILTGGDPLVLSPRRLSDLMKRLRDI
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEECHHHHHHHHHHHHCC
PHVKIVRFHTRVPVVDPDRIDAPLIEALKASGKTTYVALHANHARELGDAARNACARLID
CCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
AGIAMVSQTVLLKGINDDPAVLADLMRSFVENRIKPYYLHHPDLAPGTSHFRLTIEEGQR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEHHHHHH
IVSALRGHVSGLCQPTYVLDIPGGHGKAMIGRNAAEKTRDGCYSVSDFNGNDHIYPPATS
HHHHHHHHHHCCCCCCEEEECCCCCCCEECCCCHHHHHHCCCEEECCCCCCCCCCCCCCC
GSY
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]