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The map label for this gene is macA [H]

Identifier: 15889793

GI number: 15889793

Start: 2501103

End: 2502158

Strand: Reverse

Name: macA [H]

Synonym: Atu2528

Alternate gene names: 15889793

Gene position: 2502158-2501103 (Counterclockwise)

Preceding gene: 15889794

Following gene: 15889792

Centisome position: 88.06

GC content: 65.06

Gene sequence:

>1056_bases
ATGCAGCCTTTCGTCTATATGGCTGCGCCCGCCCGCATCGTCTTTTCGGCGGGCAGTTCGGCTGATGTGGCGGAGGAAAT
CCGCCGCCTAGGCCTGTCGCGGGCGCTGGTGCTGTCCACGCCGCAACAAAAGGGCGACGCCGAGGCGCTGGCGTCCAGGC
TTGGTCGGCTCGCGGCGGGCGTCTTTTCCGAAGCCGCTATGCATACACCGGTCGAAGTGACGAAAACGGCGGTTGAGGCC
TATCGCGCTGCGGGTGCGGATTGTGTCGTCTCTTTGGGTGGCGGTTCCACCACCGGTCTCGGCAAGGCGATTGCGCTGCG
TACCGATGCGGCGCAAATCGTCATACCCACGACCTATGCCGGCTCGGAAGTCACACCCATTCTCGGCCAGACGGAGAATG
GTGTGAAAACCACCATGCGCGGGCCGGAGATCCTGCCGGAGGTGGTGATCTATGATGCGGAACTGACCCTCGGGCTGCCT
GTCGCCATCAGCATGACGAGCGGGCTCAACGCCATGGCCCATGCGGCGGAAGCGCTTTATGCGCGGGATCGCAACCCCAT
CGCCAGCATGATGGCGGTGGAAGGGCTGCGGGCAATGATCGAAGCGCTTCCAGTCGTTCGGCAGGCGCCACACGATATCG
GCGCGCGTGAAACGGCACTTTATGGCGCGTGGCTCTGCGGCACCGTGCTGGGTGCGGTCGGCATGTCGCTGCATCACAAG
CTTTGCCACACGCTGGGCGGTAGTCTCGATCTGCCGCATGCGGAAACCCATGCGGTGCTTCTGCCGCACACCATCGCTTA
TGTGGAAGAGGCCGCGCCGAATTTGCTCGCGCCATTGGCTGCGCTGGTTGGCGGCCGGGCCGGGGCGGGACTTTTCGATT
TTGCTGCGCGGCTCGGCGCACCTTCGAGCCTGGCGGCCCTTGGCGTTGGGGCTGACGATCTCGATCCCATGGCCGAGCTT
GCGACGGCCAATCCTTACTGGTGCCCGCGGCCGATTGAAAAAACCGCGATCCGCGACCTGCTGCAGCGCGCCTTCGAGGG
CGCGCGGCCAGCGTGA

Upstream 100 bases:

>100_bases
CTCCGACTGGTTCCATGCGACGAGCATTGCCGAGGCCGACCGGGTGAAGATCGGCCGCACCAATGCGCGCCGCCTGTTCA
AGCTTGACGGGCGCTGAACC

Downstream 100 bases:

>100_bases
TGGGAGGAGACTATGGATATTAAGATGACCAGTGACGACGGCTATTTCGTCGAGGAACGCTCGGCCGAAACCGTGATTGC
CCGCATGCGCGATTGTGACG

Product: maleylacetate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MQPFVYMAAPARIVFSAGSSADVAEEIRRLGLSRALVLSTPQQKGDAEALASRLGRLAAGVFSEAAMHTPVEVTKTAVEA
YRAAGADCVVSLGGGSTTGLGKAIALRTDAAQIVIPTTYAGSEVTPILGQTENGVKTTMRGPEILPEVVIYDAELTLGLP
VAISMTSGLNAMAHAAEALYARDRNPIASMMAVEGLRAMIEALPVVRQAPHDIGARETALYGAWLCGTVLGAVGMSLHHK
LCHTLGGSLDLPHAETHAVLLPHTIAYVEEAAPNLLAPLAALVGGRAGAGLFDFAARLGAPSSLAALGVGADDLDPMAEL
ATANPYWCPRPIEKTAIRDLLQRAFEGARPA

Sequences:

>Translated_351_residues
MQPFVYMAAPARIVFSAGSSADVAEEIRRLGLSRALVLSTPQQKGDAEALASRLGRLAAGVFSEAAMHTPVEVTKTAVEA
YRAAGADCVVSLGGGSTTGLGKAIALRTDAAQIVIPTTYAGSEVTPILGQTENGVKTTMRGPEILPEVVIYDAELTLGLP
VAISMTSGLNAMAHAAEALYARDRNPIASMMAVEGLRAMIEALPVVRQAPHDIGARETALYGAWLCGTVLGAVGMSLHHK
LCHTLGGSLDLPHAETHAVLLPHTIAYVEEAAPNLLAPLAALVGGRAGAGLFDFAARLGAPSSLAALGVGADDLDPMAEL
ATANPYWCPRPIEKTAIRDLLQRAFEGARPA
>Mature_351_residues
MQPFVYMAAPARIVFSAGSSADVAEEIRRLGLSRALVLSTPQQKGDAEALASRLGRLAAGVFSEAAMHTPVEVTKTAVEA
YRAAGADCVVSLGGGSTTGLGKAIALRTDAAQIVIPTTYAGSEVTPILGQTENGVKTTMRGPEILPEVVIYDAELTLGLP
VAISMTSGLNAMAHAAEALYARDRNPIASMMAVEGLRAMIEALPVVRQAPHDIGARETALYGAWLCGTVLGAVGMSLHHK
LCHTLGGSLDLPHAETHAVLLPHTIAYVEEAAPNLLAPLAALVGGRAGAGLFDFAARLGAPSSLAALGVGADDLDPMAEL
ATANPYWCPRPIEKTAIRDLLQRAFEGARPA

Specific function: May Act On The Acetaldehyde Produced From The Degradation Of Ethanolamine. [C]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87082107, Length=212, Percent_Identity=30.6603773584906, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI48994951, Length=365, Percent_Identity=25.2054794520548, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789163, Length=368, Percent_Identity=24.1847826086957, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787493, Length=311, Percent_Identity=25.08038585209, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321181, Length=378, Percent_Identity=26.1904761904762, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.3.1.32 [H]

Molecular weight: Translated: 36325; Mature: 36325

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPFVYMAAPARIVFSAGSSADVAEEIRRLGLSRALVLSTPQQKGDAEALASRLGRLAAG
CCCCEEEECCCEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
VFSEAAMHTPVEVTKTAVEAYRAAGADCVVSLGGGSTTGLGKAIALRTDAAQIVIPTTYA
HHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECCCCEEEEEECCC
GSEVTPILGQTENGVKTTMRGPEILPEVVIYDAELTLGLPVAISMTSGLNAMAHAAEALY
CCCCCCCCCCCCCCCCCCCCCCHHCCHHEEECCEEEECCCEEEEECCCHHHHHHHHHHHH
ARDRNPIASMMAVEGLRAMIEALPVVRQAPHDIGARETALYGAWLCGTVLGAVGMSLHHK
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LCHTLGGSLDLPHAETHAVLLPHTIAYVEEAAPNLLAPLAALVGGRAGAGLFDFAARLGA
HHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHCC
PSSLAALGVGADDLDPMAELATANPYWCPRPIEKTAIRDLLQRAFEGARPA
CCHHHEECCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQPFVYMAAPARIVFSAGSSADVAEEIRRLGLSRALVLSTPQQKGDAEALASRLGRLAAG
CCCCEEEECCCEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
VFSEAAMHTPVEVTKTAVEAYRAAGADCVVSLGGGSTTGLGKAIALRTDAAQIVIPTTYA
HHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECCCCEEEEEECCC
GSEVTPILGQTENGVKTTMRGPEILPEVVIYDAELTLGLPVAISMTSGLNAMAHAAEALY
CCCCCCCCCCCCCCCCCCCCCCHHCCHHEEECCEEEECCCEEEEECCCHHHHHHHHHHHH
ARDRNPIASMMAVEGLRAMIEALPVVRQAPHDIGARETALYGAWLCGTVLGAVGMSLHHK
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LCHTLGGSLDLPHAETHAVLLPHTIAYVEEAAPNLLAPLAALVGGRAGAGLFDFAARLGA
HHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHCC
PSSLAALGVGADDLDPMAELATANPYWCPRPIEKTAIRDLLQRAFEGARPA
CCHHHEECCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7538273 [H]