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The map label for this gene is mexE [H]

Identifier: 15889750

GI number: 15889750

Start: 2448618

End: 2449808

Strand: Direct

Name: mexE [H]

Synonym: Atu2482

Alternate gene names: 15889750

Gene position: 2448618-2449808 (Clockwise)

Preceding gene: 159185233

Following gene: 15889751

Centisome position: 86.17

GC content: 64.48

Gene sequence:

>1191_bases
ATGACGCTGAACACAAAGCGCCGGGCCCTGACGGGTGCCGGCATCGGGCTTGCCATGTCCGTTGCAGCAGGAGCACTGTT
TTTCGACCTCCCCACCAGCCGCAATGCGACGGCCGCGTCCACGCCCGCCGAAACGCCGGCAATCCCGGTCACCGTCGCCA
AGGTGGAGAGCCGCGACGTGATGCGCTGGGAAGAATTTTCCGGCCGTCTGGAGGCCGTTGACCGCGTGCAGATCCGCTCC
CGCGTCGCCGGCCAGATCAAGGCCGTACATTTCCGCGAAGGCGCGCTGGTGAAGGAAGGTGACCCGCTCTTCACCATCGA
CCCGGCCCCCTATCAGGCCGCAGTCGCGGGCGCTGAAGGACAGGTCGCTTCCGCCGAAGCCAAGGTCAGCCTTGCAAAGA
CGGAACTCGACCGTGGCCGCAGGCTTTCCGATAACCGTACCATCTCCCAGAGTGATCTCGACCAGCGTCAAAGCTCGTTT
GCGGATGCCGAAGCCCAGCTTCGCGCCGCCCGCGCAGCATTGACCACCGCCCAGCTTGATCTCGGTTACACCGAAATCAT
CGCGCCGGTTTCCGGCAGGGTCGGCAGGATCGAAATCACCGCCGGCAATCTCGTCGCTGCGGGCTCCACCTCGCCGGCAC
TGACCACGCTCGTCTCGGTCAACCCGATCTATGCAAGCTTCAACGCCAGCGAAGGCGTCGTGGCCAAGGCTCTTGCCGAG
CTGCCGAAGACCGATGGCGCCCTGCCCGCTCTGGAACAGATCCCGGTGGAAATCGGCACGCTTTCGGATGAAGGCACGCC
GATCAAGGGCACGCTGCACCTGATCGACAACCAGGTGGATTCGGCAAGCGGCACCATCGGTGTGCGCGCCATCTTCGACA
ATCCGGATGGCAGGCTGATCCCCGGCCAGTTCGTGCGGGTACGCATGGGCGAACCGAAGCCGGAAAACCGCATCGTCATC
AGCGACCGCGCCATCGGCACGGATCAGGACAAGCGCTTCGTCTTCGTGGTCGATGCCGAAAACAAGGTAAGCTACCGCCA
GATCAAGCCCGGCGCACCGGCTGATGGCCAGCGCATCATCGACAGCGGCCTTGCCGCCGGTGATACGATCGTCGTCAACG
GCCTGCAGCGCATCCGTCCCGGTGCGACCATCGCGCCCCAGGCGGAAGACAAGGTTGCTGCTTCGCAGTAA

Upstream 100 bases:

>100_bases
TCTGTTCGGAGTTCAAGACCTTCGTTGACCAATTGAAACACTGAATACCGCATTTATTGAGAAACTGATCGGCTCCTGAT
CTGGGGCCAAGGAGATACCC

Downstream 100 bases:

>100_bases
CCCACCTCTTTGATCAGTAAGCGTCCCGCAGTATCGCGAGACGCGCATTCACACAGAACCGGCCTTCACCGGCGGCAGGA
TTGCCGCCGGAACAGCCTTC

Product: HlyD family secretion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTLNTKRRALTGAGIGLAMSVAAGALFFDLPTSRNATAASTPAETPAIPVTVAKVESRDVMRWEEFSGRLEAVDRVQIRS
RVAGQIKAVHFREGALVKEGDPLFTIDPAPYQAAVAGAEGQVASAEAKVSLAKTELDRGRRLSDNRTISQSDLDQRQSSF
ADAEAQLRAARAALTTAQLDLGYTEIIAPVSGRVGRIEITAGNLVAAGSTSPALTTLVSVNPIYASFNASEGVVAKALAE
LPKTDGALPALEQIPVEIGTLSDEGTPIKGTLHLIDNQVDSASGTIGVRAIFDNPDGRLIPGQFVRVRMGEPKPENRIVI
SDRAIGTDQDKRFVFVVDAENKVSYRQIKPGAPADGQRIIDSGLAAGDTIVVNGLQRIRPGATIAPQAEDKVAASQ

Sequences:

>Translated_396_residues
MTLNTKRRALTGAGIGLAMSVAAGALFFDLPTSRNATAASTPAETPAIPVTVAKVESRDVMRWEEFSGRLEAVDRVQIRS
RVAGQIKAVHFREGALVKEGDPLFTIDPAPYQAAVAGAEGQVASAEAKVSLAKTELDRGRRLSDNRTISQSDLDQRQSSF
ADAEAQLRAARAALTTAQLDLGYTEIIAPVSGRVGRIEITAGNLVAAGSTSPALTTLVSVNPIYASFNASEGVVAKALAE
LPKTDGALPALEQIPVEIGTLSDEGTPIKGTLHLIDNQVDSASGTIGVRAIFDNPDGRLIPGQFVRVRMGEPKPENRIVI
SDRAIGTDQDKRFVFVVDAENKVSYRQIKPGAPADGQRIIDSGLAAGDTIVVNGLQRIRPGATIAPQAEDKVAASQ
>Mature_395_residues
TLNTKRRALTGAGIGLAMSVAAGALFFDLPTSRNATAASTPAETPAIPVTVAKVESRDVMRWEEFSGRLEAVDRVQIRSR
VAGQIKAVHFREGALVKEGDPLFTIDPAPYQAAVAGAEGQVASAEAKVSLAKTELDRGRRLSDNRTISQSDLDQRQSSFA
DAEAQLRAARAALTTAQLDLGYTEIIAPVSGRVGRIEITAGNLVAAGSTSPALTTLVSVNPIYASFNASEGVVAKALAEL
PKTDGALPALEQIPVEIGTLSDEGTPIKGTLHLIDNQVDSASGTIGVRAIFDNPDGRLIPGQFVRVRMGEPKPENRIVIS
DRAIGTDQDKRFVFVVDAENKVSYRQIKPGAPADGQRIIDSGLAAGDTIVVNGLQRIRPGATIAPQAEDKVAASQ

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=339, Percent_Identity=34.5132743362832, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1789929, Length=358, Percent_Identity=31.2849162011173, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786668, Length=347, Percent_Identity=34.2939481268012, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1789665, Length=337, Percent_Identity=32.6409495548961, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI87081796, Length=333, Percent_Identity=26.4264264264264, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081951, Length=237, Percent_Identity=30.8016877637131, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789637, Length=212, Percent_Identity=30.6603773584906, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41678; Mature: 41546

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNTKRRALTGAGIGLAMSVAAGALFFDLPTSRNATAASTPAETPAIPVTVAKVESRDV
CCCCCCHHEEECCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
MRWEEFSGRLEAVDRVQIRSRVAGQIKAVHFREGALVKEGDPLFTIDPAPYQAAVAGAEG
HHHHHHCCHHHHHHHHHHHHHHHCCEEEEEEECCCEEECCCCEEEECCCCCEEEEECCCC
QVASAEAKVSLAKTELDRGRRLSDNRTISQSDLDQRQSSFADAEAQLRAARAALTTAQLD
CEECCHHEEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEC
LGYTEIIAPVSGRVGRIEITAGNLVAAGSTSPALTTLVSVNPIYASFNASEGVVAKALAE
CCHHHEECCCCCCEEEEEEEECCEEEECCCCCCEEEEEECCCEEEECCCCCCHHHHHHHH
LPKTDGALPALEQIPVEIGTLSDEGTPIKGTLHLIDNQVDSASGTIGVRAIFDNPDGRLI
CCCCCCCCCHHHHCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCCCCC
PGQFVRVRMGEPKPENRIVISDRAIGTDQDKRFVFVVDAENKVSYRQIKPGAPADGQRII
CCEEEEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHH
DSGLAAGDTIVVNGLQRIRPGATIAPQAEDKVAASQ
HCCCCCCCEEEECCHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLNTKRRALTGAGIGLAMSVAAGALFFDLPTSRNATAASTPAETPAIPVTVAKVESRDV
CCCCCHHEEECCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
MRWEEFSGRLEAVDRVQIRSRVAGQIKAVHFREGALVKEGDPLFTIDPAPYQAAVAGAEG
HHHHHHCCHHHHHHHHHHHHHHHCCEEEEEEECCCEEECCCCEEEECCCCCEEEEECCCC
QVASAEAKVSLAKTELDRGRRLSDNRTISQSDLDQRQSSFADAEAQLRAARAALTTAQLD
CEECCHHEEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEC
LGYTEIIAPVSGRVGRIEITAGNLVAAGSTSPALTTLVSVNPIYASFNASEGVVAKALAE
CCHHHEECCCCCCEEEEEEEECCEEEECCCCCCEEEEEECCCEEEECCCCCCHHHHHHHH
LPKTDGALPALEQIPVEIGTLSDEGTPIKGTLHLIDNQVDSASGTIGVRAIFDNPDGRLI
CCCCCCCCCHHHHCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCCCCC
PGQFVRVRMGEPKPENRIVISDRAIGTDQDKRFVFVVDAENKVSYRQIKPGAPADGQRII
CCEEEEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHH
DSGLAAGDTIVVNGLQRIRPGATIAPQAEDKVAASQ
HCCCCCCCEEEECCHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA