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The map label for this gene is czcR [H]

Identifier: 15889689

GI number: 15889689

Start: 2391887

End: 2392816

Strand: Direct

Name: czcR [H]

Synonym: Atu2419

Alternate gene names: 15889689

Gene position: 2391887-2392816 (Clockwise)

Preceding gene: 15889688

Following gene: 15889690

Centisome position: 84.17

GC content: 63.33

Gene sequence:

>930_bases
ATGAGCGGTCAGGTAGCAGCGGCTCCCAGAGACATCGTCCTGCTGGTGGATGACAGCCCGGACGCGCTGGGTTTCCTGAC
CGATGCGCTGGAACAGTCAGGCTTTTCCGCCCTCATCGCCACTTCGGGTCAGGCAGCCCTCAACATTGCCGAACGCATCA
CCCCCGATATCATCCTGCTCGACGCCGTCATGCCTGTTATGGACGGTTTCGAGACCTGCCGCCGCCTGAAGGCCAATGCG
GCGGTGGCGCAGGTGCCCGTCATCTTCATGACCGGGTTGACCGAAACAGAACATGTGGTGCGGGCGCTGGAATCCGGCGG
GGTCGACTATCTGACCAAGCCGATCAACATCGATGAGTTGCGCGCCCGCATCCGCGTGCATCTCTCCAATGCCCGCTCGG
CCCAGAGTGCCCGCGTGGCGCTCGATGCCGCCGGGCGTCACCTGCTCGCCGTGCGCGCCAATGGCGCCATCCACTGGTCC
ACCCCACAGGCAACCCGTCTGGTCAACGCCGCCACCGGCCGCGATGACGGTCTGGAGATTGTCGTCGCCCATATTTCCGG
CTGGCTGAAGGAGCGGGCGACGGTGGATGCTGCCCGCGACGCCCCGCTGACGATCACCGAGGCCGGACGGCCTGCCCTGC
AACTCTCCTTCCTCGGCGCGATGGGACCGGACGAATATCTCTTCCGCCTGACCGCCGCCAACGAGAAATCCGACGACCAT
CTGCTGAAAAGCCATTTCGCCCTGACGACACGGGAATCGGAAGTGCTGTTATGGATCGCCAAGGGCAAATCCAACCGCGA
TATCGGCGATATTCTCGGCCTTTCCGCCAGAACCGTGAACAAACATCTGGAGCAGATTTACGTCAAGCTCGGCGTCGAAA
ACCGCGCTTCGGCGGCCGTCAAGGCGGCACATGTCCTGCATCAGGGGTGA

Upstream 100 bases:

>100_bases
TCACGCAAGAGCTCGGCACCTATGTGCAGGCCTTCGATCTGGCCGGTTACGCCCATTTTCTCAAGCGGTTTGAAGACAAC
GACAGGGGAGACGGCGGGGC

Downstream 100 bases:

>100_bases
CGGATGCGTTTAGTGTGGTAAGATTCAACAAACATATATTTTCCGCTTGAACGTAAGGCATTCGCCTATTGAGCGAGCGG
TGGCCGCGTCTTTCTTCTCC

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSGQVAAAPRDIVLLVDDSPDALGFLTDALEQSGFSALIATSGQAALNIAERITPDIILLDAVMPVMDGFETCRRLKANA
AVAQVPVIFMTGLTETEHVVRALESGGVDYLTKPINIDELRARIRVHLSNARSAQSARVALDAAGRHLLAVRANGAIHWS
TPQATRLVNAATGRDDGLEIVVAHISGWLKERATVDAARDAPLTITEAGRPALQLSFLGAMGPDEYLFRLTAANEKSDDH
LLKSHFALTTRESEVLLWIAKGKSNRDIGDILGLSARTVNKHLEQIYVKLGVENRASAAVKAAHVLHQG

Sequences:

>Translated_309_residues
MSGQVAAAPRDIVLLVDDSPDALGFLTDALEQSGFSALIATSGQAALNIAERITPDIILLDAVMPVMDGFETCRRLKANA
AVAQVPVIFMTGLTETEHVVRALESGGVDYLTKPINIDELRARIRVHLSNARSAQSARVALDAAGRHLLAVRANGAIHWS
TPQATRLVNAATGRDDGLEIVVAHISGWLKERATVDAARDAPLTITEAGRPALQLSFLGAMGPDEYLFRLTAANEKSDDH
LLKSHFALTTRESEVLLWIAKGKSNRDIGDILGLSARTVNKHLEQIYVKLGVENRASAAVKAAHVLHQG
>Mature_308_residues
SGQVAAAPRDIVLLVDDSPDALGFLTDALEQSGFSALIATSGQAALNIAERITPDIILLDAVMPVMDGFETCRRLKANAA
VAQVPVIFMTGLTETEHVVRALESGGVDYLTKPINIDELRARIRVHLSNARSAQSARVALDAAGRHLLAVRANGAIHWST
PQATRLVNAATGRDDGLEIVVAHISGWLKERATVDAARDAPLTITEAGRPALQLSFLGAMGPDEYLFRLTAANEKSDDHL
LKSHFALTTRESEVLLWIAKGKSNRDIGDILGLSARTVNKHLEQIYVKLGVENRASAAVKAAHVLHQG

Specific function: Member of the two-component regulatory system CzcS/CzcR involved in the control of cobalt, zinc and cadmium homeostasis [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=37.037037037037, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=36.283185840708, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790860, Length=124, Percent_Identity=33.8709677419355, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790437, Length=195, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786911, Length=116, Percent_Identity=40.5172413793103, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790299, Length=129, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786784, Length=116, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082012, Length=116, Percent_Identity=32.7586206896552, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788394, Length=124, Percent_Identity=27.4193548387097, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI145693157, Length=126, Percent_Identity=30.952380952381, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 33107; Mature: 32976

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQVAAAPRDIVLLVDDSPDALGFLTDALEQSGFSALIATSGQAALNIAERITPDIILL
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCEEEH
DAVMPVMDGFETCRRLKANAAVAQVPVIFMTGLTETEHVVRALESGGVDYLTKPINIDEL
HHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCHHHHHHHHHHHCCCCEEECCCCHHHH
RARIRVHLSNARSAQSARVALDAAGRHLLAVRANGAIHWSTPQATRLVNAATGRDDGLEI
HHHHEEEECCCCCCCHHEEEEECCCCEEEEEEECCEEEECCCHHHHHEECCCCCCCCCEE
VVAHISGWLKERATVDAARDAPLTITEAGRPALQLSFLGAMGPDEYLFRLTAANEKSDDH
EHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCEEEEEEECCCCCCHH
LLKSHFALTTRESEVLLWIAKGKSNRDIGDILGLSARTVNKHLEQIYVKLGVENRASAAV
HHHHHHEEEECCCEEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHH
KAAHVLHQG
HHHHHHCCC
>Mature Secondary Structure 
SGQVAAAPRDIVLLVDDSPDALGFLTDALEQSGFSALIATSGQAALNIAERITPDIILL
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCEEEH
DAVMPVMDGFETCRRLKANAAVAQVPVIFMTGLTETEHVVRALESGGVDYLTKPINIDEL
HHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCHHHHHHHHHHHCCCCEEECCCCHHHH
RARIRVHLSNARSAQSARVALDAAGRHLLAVRANGAIHWSTPQATRLVNAATGRDDGLEI
HHHHEEEECCCCCCCHHEEEEECCCCEEEEEEECCEEEECCCHHHHHEECCCCCCCCCEE
VVAHISGWLKERATVDAARDAPLTITEAGRPALQLSFLGAMGPDEYLFRLTAANEKSDDH
EHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCEEEEEEECCCCCCHH
LLKSHFALTTRESEVLLWIAKGKSNRDIGDILGLSARTVNKHLEQIYVKLGVENRASAAV
HHHHHHEEEECCCEEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHH
KAAHVLHQG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9044283 [H]