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The map label for this gene is map [H]

Identifier: 15889582

GI number: 15889582

Start: 2281962

End: 2282714

Strand: Reverse

Name: map [H]

Synonym: Atu2306

Alternate gene names: 15889582

Gene position: 2282714-2281962 (Counterclockwise)

Preceding gene: 15889583

Following gene: 15889581

Centisome position: 80.33

GC content: 60.56

Gene sequence:

>753_bases
ATGGTTATTTCCACCGACGAAGAACTTGATCTGCTGAAGGATATCGGCCGTCTTTGCGCCGTGGCCATGCAGACCATGGC
GGACGCGCTGGAACCCGGCATCACCACGGCCGAGCTGGATGCGATCGGCCGCAAGGTGCTGGAGGATAACGGCGCGCAAT
CCGCGCCGGAGTTCTGCTACAAATTTCCCGGCGCGACCTGCATCAGCGTCAACGAGGAAGTGGCCCACGGCATTCCCGGC
CCGCGCATCATCAAGGCAGGCGATCTCGTCAATATCGATGTCTCGGCGGTGAAAAACGGCTTTTTCGGTGACACGGGTTC
GTCCTTCGCCGTGCCGCCTGTCAAAAAGGACATCGAGCGGCTGTGCCGCGATGGCAAACGCGCCATGTGGACCGGCCTGC
AACAGGTAAAAACCGGCCGGCCCTTCGCCGATATCGGCAATGCCATCGGCGCCTTTGCCAAAAAGAACCGCTATACGCTG
ATCACCAATCTGGCGAGCCACGGCATAGGTCGTTCGCTGCATGAGGAGCCGAAGGAGTTGGCGACCTGGCCGGACAAGGA
TGAGCGCCGCATCATGCAGGAAGGCATGGTGTTCACCGTCGAGCCGTTTCTTTCGACAGGGGCCTATTGGGCTGAAGATG
GCGACGATGATCCTTGGACGCTCTACAGCGATCCGAGCGCGCCGACCGTGCAGTATGAGCATACGGTGGTGGCGACGAAG
AACGGGCCGCTGGTGTTGACGCTGGTTGAGTGA

Upstream 100 bases:

>100_bases
AAAAGAATTGACGGGGAGCGCCGATCCGGTGAAAGCCACGGCCTGATGATTACCAAGGCGGGCGTTTTCAGACCCGCCAG
ACAGAACGACGGACAGAGAC

Downstream 100 bases:

>100_bases
CAAATCCGTTCTTGCGAAGAATGATGGTGCTTGCTCGCCGTTAAGATAAGGTGAGCGGCTGCGGCATTTTTCTTCTCCCC
GGCGTGGAGAAGAAACAAGC

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MVISTDEELDLLKDIGRLCAVAMQTMADALEPGITTAELDAIGRKVLEDNGAQSAPEFCYKFPGATCISVNEEVAHGIPG
PRIIKAGDLVNIDVSAVKNGFFGDTGSSFAVPPVKKDIERLCRDGKRAMWTGLQQVKTGRPFADIGNAIGAFAKKNRYTL
ITNLASHGIGRSLHEEPKELATWPDKDERRIMQEGMVFTVEPFLSTGAYWAEDGDDDPWTLYSDPSAPTVQYEHTVVATK
NGPLVLTLVE

Sequences:

>Translated_250_residues
MVISTDEELDLLKDIGRLCAVAMQTMADALEPGITTAELDAIGRKVLEDNGAQSAPEFCYKFPGATCISVNEEVAHGIPG
PRIIKAGDLVNIDVSAVKNGFFGDTGSSFAVPPVKKDIERLCRDGKRAMWTGLQQVKTGRPFADIGNAIGAFAKKNRYTL
ITNLASHGIGRSLHEEPKELATWPDKDERRIMQEGMVFTVEPFLSTGAYWAEDGDDDPWTLYSDPSAPTVQYEHTVVATK
NGPLVLTLVE
>Mature_250_residues
MVISTDEELDLLKDIGRLCAVAMQTMADALEPGITTAELDAIGRKVLEDNGAQSAPEFCYKFPGATCISVNEEVAHGIPG
PRIIKAGDLVNIDVSAVKNGFFGDTGSSFAVPPVKKDIERLCRDGKRAMWTGLQQVKTGRPFADIGNAIGAFAKKNRYTL
ITNLASHGIGRSLHEEPKELATWPDKDERRIMQEGMVFTVEPFLSTGAYWAEDGDDDPWTLYSDPSAPTVQYEHTVVATK
NGPLVLTLVE

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=243, Percent_Identity=28.8065843621399, Blast_Score=134, Evalue=5e-32,
Organism=Homo sapiens, GI40385867, Length=242, Percent_Identity=30.9917355371901, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI1786364, Length=248, Percent_Identity=36.2903225806452, Blast_Score=166, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71996291, Length=246, Percent_Identity=32.1138211382114, Blast_Score=134, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6323273, Length=242, Percent_Identity=30.1652892561983, Blast_Score=130, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21355531, Length=242, Percent_Identity=32.6446280991736, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24583427, Length=246, Percent_Identity=31.3008130081301, Blast_Score=117, Evalue=7e-27,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27184; Mature: 27184

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVISTDEELDLLKDIGRLCAVAMQTMADALEPGITTAELDAIGRKVLEDNGAQSAPEFCY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHH
KFPGATCISVNEEVAHGIPGPRIIKAGDLVNIDVSAVKNGFFGDTGSSFAVPPVKKDIER
HCCCCEEEECCHHHHHCCCCCEEEECCCEEEEEHHHHCCCCCCCCCCCCCCCCHHHHHHH
LCRDGKRAMWTGLQQVKTGRPFADIGNAIGAFAKKNRYTLITNLASHGIGRSLHEEPKEL
HHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCHHHHCHHHH
ATWPDKDERRIMQEGMVFTVEPFLSTGAYWAEDGDDDPWTLYSDPSAPTVQYEHTVVATK
CCCCCHHHHHHHHCCCEEEECHHHHCCCEECCCCCCCCEEEECCCCCCEEEEEEEEEEEC
NGPLVLTLVE
CCCEEEEEEC
>Mature Secondary Structure
MVISTDEELDLLKDIGRLCAVAMQTMADALEPGITTAELDAIGRKVLEDNGAQSAPEFCY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHH
KFPGATCISVNEEVAHGIPGPRIIKAGDLVNIDVSAVKNGFFGDTGSSFAVPPVKKDIER
HCCCCEEEECCHHHHHCCCCCEEEECCCEEEEEHHHHCCCCCCCCCCCCCCCCHHHHHHH
LCRDGKRAMWTGLQQVKTGRPFADIGNAIGAFAKKNRYTLITNLASHGIGRSLHEEPKEL
HHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCHHHHCHHHH
ATWPDKDERRIMQEGMVFTVEPFLSTGAYWAEDGDDDPWTLYSDPSAPTVQYEHTVVATK
CCCCCHHHHHHHHCCCEEEECHHHHCCCEECCCCCCCCEEEECCCCCCEEEEEEEEEEEC
NGPLVLTLVE
CCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA