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The map label for this gene is lrp [H]

Identifier: 15889464

GI number: 15889464

Start: 2160439

End: 2161029

Strand: Reverse

Name: lrp [H]

Synonym: Atu2184

Alternate gene names: 15889464

Gene position: 2161029-2160439 (Counterclockwise)

Preceding gene: 159185094

Following gene: 159185091

Centisome position: 76.05

GC content: 57.53

Gene sequence:

>591_bases
TTGCGTTACCAACAAGGCAGTTGTGGATGTGTGCGCAATTTTGTGACCGGGCGTTGGCATAATGTTGCGAATCCTGCGCC
GAATAGTACAAGGAAGTTCTCCAGCTTAACGAGGTACTTCTCCGTGACCAGCGTCGAACTCGATGCCATCGATCTGAAAA
TCCTGCGCGAATTGCAGCGCGACGGGCGCATGACCAACGTGGAGCTGGCCGAAAGGGTCGGAATTTCCGCACCGCCATGC
CTCAGGCGTGTCCGCAAGCTGGAAGAAGCTGACGTGATCCAGGGTTATCACGCCATGTTGAACGCGCCGAAGCTTGGTTT
CGACCTCGTCGCCTTCTGCATGATTGGCCTCAAGCGCCAGTCCGACAGTAATCTGAAGGCCTTTGCGGCGGCGACGGGCG
GATGGTCGCTGGTGCGGCAGGCCTGGATGGTGTCGGGCGAAAGCGATTTCCTGCTGCATTGCGTCGCGAAGAACCTGACG
GAGTTTCAGGATTTCGTCATCGAGGTTCTGACGGCGGATGAGAATGTCGACACGGTGCGCACCATGCTGACCATCCGTCA
GGTCAAGCGTGTCGGCCTCGTGGAAATCTGA

Upstream 100 bases:

>100_bases
TTCGGCGGCAAAGCCATCCAGCCGCAAGACGGCGGATAGGCCGCAACCCCTTCGTTGCCCGGTATTTAAGGTTGTCTAGT
GTCTTTATTCAAGGGCAGCC

Downstream 100 bases:

>100_bases
GCAGCCGGCTTTTAGCCGATTTTGGGGATATCACCCCCGCTGTAACGCCTCATAGACTTCACCGAGGCATGTCGCTTCTT
TTTCCAGCGGGAAAGTGCTG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MRYQQGSCGCVRNFVTGRWHNVANPAPNSTRKFSSLTRYFSVTSVELDAIDLKILRELQRDGRMTNVELAERVGISAPPC
LRRVRKLEEADVIQGYHAMLNAPKLGFDLVAFCMIGLKRQSDSNLKAFAAATGGWSLVRQAWMVSGESDFLLHCVAKNLT
EFQDFVIEVLTADENVDTVRTMLTIRQVKRVGLVEI

Sequences:

>Translated_196_residues
MRYQQGSCGCVRNFVTGRWHNVANPAPNSTRKFSSLTRYFSVTSVELDAIDLKILRELQRDGRMTNVELAERVGISAPPC
LRRVRKLEEADVIQGYHAMLNAPKLGFDLVAFCMIGLKRQSDSNLKAFAAATGGWSLVRQAWMVSGESDFLLHCVAKNLT
EFQDFVIEVLTADENVDTVRTMLTIRQVKRVGLVEI
>Mature_196_residues
MRYQQGSCGCVRNFVTGRWHNVANPAPNSTRKFSSLTRYFSVTSVELDAIDLKILRELQRDGRMTNVELAERVGISAPPC
LRRVRKLEEADVIQGYHAMLNAPKLGFDLVAFCMIGLKRQSDSNLKAFAAATGGWSLVRQAWMVSGESDFLLHCVAKNLT
EFQDFVIEVLTADENVDTVRTMLTIRQVKRVGLVEI

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=145, Percent_Identity=38.6206896551724, Blast_Score=106, Evalue=9e-25,
Organism=Escherichia coli, GI87081742, Length=143, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 22025; Mature: 22025

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYQQGSCGCVRNFVTGRWHNVANPAPNSTRKFSSLTRYFSVTSVELDAIDLKILRELQR
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHH
DGRMTNVELAERVGISAPPCLRRVRKLEEADVIQGYHAMLNAPKLGFDLVAFCMIGLKRQ
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
SDSNLKAFAAATGGWSLVRQAWMVSGESDFLLHCVAKNLTEFQDFVIEVLTADENVDTVR
CCCCCEEEHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TMLTIRQVKRVGLVEI
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRYQQGSCGCVRNFVTGRWHNVANPAPNSTRKFSSLTRYFSVTSVELDAIDLKILRELQR
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHH
DGRMTNVELAERVGISAPPCLRRVRKLEEADVIQGYHAMLNAPKLGFDLVAFCMIGLKRQ
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
SDSNLKAFAAATGGWSLVRQAWMVSGESDFLLHCVAKNLTEFQDFVIEVLTADENVDTVR
CCCCCEEEHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TMLTIRQVKRVGLVEI
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]