| Definition | Agrobacterium tumefaciens str. C58 chromosome circular, complete sequence. |
|---|---|
| Accession | NC_003062 |
| Length | 2,841,580 |
Click here to switch to the map view.
The map label for this gene is gno [H]
Identifier: 15889193
GI number: 15889193
Start: 1873424
End: 1874212
Strand: Reverse
Name: gno [H]
Synonym: Atu1897
Alternate gene names: 15889193
Gene position: 1874212-1873424 (Counterclockwise)
Preceding gene: 159184969
Following gene: 17935786
Centisome position: 65.96
GC content: 62.23
Gene sequence:
>789_bases ATGTCCACCATCACCCTTAACGCCCCGAAACTGTTCGATCTTTCCGGTCAGGTGGCGCTCGTCACCGGTGCTGGATCCGG CATCGGCCAGCGGATCGCCATGGGGCTTGCCCAGTCCGGCGCCAATGTCGCGCTGCTCGACCGCCGCACCGATGACGGTC TGGCGCAGACGGCCGATTTCATCGCCAGGGCCGGCCGCAAGTCGATCCAGATCGCCGCCGACGTTACCAGCAAGCAGGCG CTGACGGATGCGGTTGCCCGCACGCAAGCCGAACTCGGCGCACTTTCGCTCGCCGTCAATGCGGCCGGCATCGCCAATGC CAATCCGGCCGAGGAGATGGAAGAAAGCCAGTTCCAGACGATGATGGACATCAACCTGAAGGGCGTGTTCCTGTCCTGCC AGGCCGAAGCCAACGCCATGCTGAAAAATGGCCGAGGTGCCATCGTCAACATCGCGTCGATGTCCGGCGTCATCGTCAAT CGAGGCCTGATGCAGTGCCATTACAACGCCTCGAAGGCGGGTGTCATCCACATGTCGAAATCCATGGCGATGGAATGGGT GGGTCGCGGCATCCGCGTCAACACCATCTCGCCGGGCTACACGGCGACACCGATGAACACGCGGCCTGAAATGGTGCACC AGACCAAGCTGTTCGAAGAGCAGACGCCGATGCAGCGCATGGCAGGCGTCGATGAAATGGTGGGACCGGCGATCTTCCTG CTGTCCGACGCCGCGAGTTTTGTGACGGGTGTGGATCTCTTGGTGGATGGCGGGTTCTGCTGCTGGTAA
Upstream 100 bases:
>100_bases TCGTGCTCGCGCAGGGAAAACAGGCTGGCATCCTTAACCGCGACGAGGCAAACGACGTCTCGGTCATGGAACTGGCAACC ATCTGAAGAAGGAAATAGCG
Downstream 100 bases:
>100_bases GGCTTGGCATGGTCGCCCAGCTTCAACGACTGATGAAGTCTGAAAAGTTCACGGCCGTCATCCTCGGGCTTGTCCCGAGG ATCTGCAACGTATTGATTTC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 262; Mature: 261
Protein sequence:
>262_residues MSTITLNAPKLFDLSGQVALVTGAGSGIGQRIAMGLAQSGANVALLDRRTDDGLAQTADFIARAGRKSIQIAADVTSKQA LTDAVARTQAELGALSLAVNAAGIANANPAEEMEESQFQTMMDINLKGVFLSCQAEANAMLKNGRGAIVNIASMSGVIVN RGLMQCHYNASKAGVIHMSKSMAMEWVGRGIRVNTISPGYTATPMNTRPEMVHQTKLFEEQTPMQRMAGVDEMVGPAIFL LSDAASFVTGVDLLVDGGFCCW
Sequences:
>Translated_262_residues MSTITLNAPKLFDLSGQVALVTGAGSGIGQRIAMGLAQSGANVALLDRRTDDGLAQTADFIARAGRKSIQIAADVTSKQA LTDAVARTQAELGALSLAVNAAGIANANPAEEMEESQFQTMMDINLKGVFLSCQAEANAMLKNGRGAIVNIASMSGVIVN RGLMQCHYNASKAGVIHMSKSMAMEWVGRGIRVNTISPGYTATPMNTRPEMVHQTKLFEEQTPMQRMAGVDEMVGPAIFL LSDAASFVTGVDLLVDGGFCCW >Mature_261_residues STITLNAPKLFDLSGQVALVTGAGSGIGQRIAMGLAQSGANVALLDRRTDDGLAQTADFIARAGRKSIQIAADVTSKQAL TDAVARTQAELGALSLAVNAAGIANANPAEEMEESQFQTMMDINLKGVFLSCQAEANAMLKNGRGAIVNIASMSGVIVNR GLMQCHYNASKAGVIHMSKSMAMEWVGRGIRVNTISPGYTATPMNTRPEMVHQTKLFEEQTPMQRMAGVDEMVGPAIFLL SDAASFVTGVDLLVDGGFCCW
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=31.9230769230769, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=36.1867704280156, Blast_Score=122, Evalue=3e-28, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=31.6, Blast_Score=117, Evalue=9e-27, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=28.8065843621399, Blast_Score=104, Evalue=9e-23, Organism=Homo sapiens, GI4758504, Length=229, Percent_Identity=34.061135371179, Blast_Score=98, Evalue=8e-21, Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=30.3501945525292, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=30.078125, Blast_Score=89, Evalue=6e-18, Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=30.6034482758621, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=28.4, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI142976729, Length=249, Percent_Identity=23.6947791164659, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI31542939, Length=198, Percent_Identity=32.3232323232323, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI83715985, Length=230, Percent_Identity=31.304347826087, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI310128830, Length=178, Percent_Identity=25.2808988764045, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI310115468, Length=178, Percent_Identity=25.2808988764045, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=27.906976744186, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI4503301, Length=257, Percent_Identity=28.7937743190661, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI40807363, Length=202, Percent_Identity=28.2178217821782, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=29.0748898678414, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI4504505, Length=201, Percent_Identity=29.8507462686567, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=27.8884462151394, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI4557649, Length=204, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI226371731, Length=204, Percent_Identity=28.4313725490196, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI224922801, Length=182, Percent_Identity=31.8681318681319, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=34.2629482071713, Blast_Score=137, Evalue=8e-34, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=35.0806451612903, Blast_Score=131, Evalue=4e-32, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=33.8582677165354, Blast_Score=126, Evalue=1e-30, Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=32.6771653543307, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI87082160, Length=265, Percent_Identity=31.6981132075472, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=30.2788844621514, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=33.8709677419355, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=32.6693227091633, Blast_Score=103, Evalue=9e-24, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=30.1960784313725, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=28.6821705426357, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1789378, Length=239, Percent_Identity=29.7071129707113, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=30.9782608695652, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=27.6422764227642, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787526, Length=252, Percent_Identity=30.5555555555556, Blast_Score=66, Evalue=3e-12, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=36, Blast_Score=128, Evalue=4e-30, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=35.4838709677419, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=31.5175097276265, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=32.4427480916031, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17538182, Length=213, Percent_Identity=36.6197183098592, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17536025, Length=265, Percent_Identity=31.6981132075472, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=26.7175572519084, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=28.4132841328413, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=29.0076335877863, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=28.9156626506024, Blast_Score=88, Evalue=6e-18, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=28.4, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=28.8461538461538, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=26.5384615384615, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=28.7179487179487, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=27.6119402985075, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=28.1368821292776, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17536651, Length=263, Percent_Identity=32.319391634981, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=27.9245283018868, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=25.1908396946565, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=29.1187739463602, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=27.0992366412214, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=27.843137254902, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=26.3959390862944, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=26.6917293233083, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=26.7716535433071, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=26.5151515151515, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17555612, Length=230, Percent_Identity=28.2608695652174, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17567345, Length=201, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=26.3940520446097, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=27.5, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=26.6917293233083, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17561272, Length=256, Percent_Identity=30.859375, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17568967, Length=191, Percent_Identity=29.3193717277487, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI32563809, Length=205, Percent_Identity=27.3170731707317, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17507613, Length=205, Percent_Identity=27.3170731707317, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=25.4752851711027, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=268, Percent_Identity=30.2238805970149, Blast_Score=81, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=29.0816326530612, Blast_Score=76, Evalue=5e-15, Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=36.6533864541833, Blast_Score=124, Evalue=7e-29, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=32.9365079365079, Blast_Score=117, Evalue=1e-26, Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=33.0645161290323, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=32.6612903225806, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=32.9457364341085, Blast_Score=114, Evalue=5e-26, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=33.4661354581673, Blast_Score=109, Evalue=1e-24, Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=33.4645669291339, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI17737361, Length=202, Percent_Identity=35.1485148514851, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI24581726, Length=209, Percent_Identity=28.2296650717703, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=27.0588235294118, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24640492, Length=155, Percent_Identity=30.9677419354839, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI281364892, Length=205, Percent_Identity=27.8048780487805, Blast_Score=81, Evalue=8e-16, Organism=Drosophila melanogaster, GI28574402, Length=212, Percent_Identity=29.2452830188679, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24584744, Length=212, Percent_Identity=29.2452830188679, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI18859837, Length=216, Percent_Identity=31.0185185185185, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24584748, Length=212, Percent_Identity=27.8301886792453, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI161076933, Length=212, Percent_Identity=27.8301886792453, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24649181, Length=203, Percent_Identity=28.0788177339901, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI21355631, Length=174, Percent_Identity=27.0114942528736, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21357673, Length=191, Percent_Identity=25.6544502617801, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24665243, Length=200, Percent_Identity=30, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI221331218, Length=234, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24640442, Length=209, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24584752, Length=212, Percent_Identity=28.7735849056604, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27587; Mature: 27456
Theoretical pI: Translated: 5.72; Mature: 5.72
Prosite motif: PS00061 ADH_SHORT ; PS00104 EPSP_SYNTHASE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 6.1 %Met (Translated Protein) 7.6 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 5.7 %Met (Mature Protein) 7.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSTITLNAPKLFDLSGQVALVTGAGSGIGQRIAMGLAQSGANVALLDRRTDDGLAQTADF CCEEEECCCEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH IARAGRKSIQIAADVTSKQALTDAVARTQAELGALSLAVNAAGIANANPAEEMEESQFQT HHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHH MMDINLKGVFLSCQAEANAMLKNGRGAIVNIASMSGVIVNRGLMQCHYNASKAGVIHMSK HHCCCEEEEEEEECCCCHHHHHCCCCEEEEEECCCCHHHHCCCEEEECCCCCCEEEEEHH SMAMEWVGRGIRVNTISPGYTATPMNTRPEMVHQTKLFEEQTPMQRMAGVDEMVGPAIFL HHHHHHHCCCEEEEEECCCCEECCCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHCHHHEE LSDAASFVTGVDLLVDGGFCCW HHHHHHHHHHHHHEECCCEECC >Mature Secondary Structure STITLNAPKLFDLSGQVALVTGAGSGIGQRIAMGLAQSGANVALLDRRTDDGLAQTADF CEEEECCCEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH IARAGRKSIQIAADVTSKQALTDAVARTQAELGALSLAVNAAGIANANPAEEMEESQFQT HHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHH MMDINLKGVFLSCQAEANAMLKNGRGAIVNIASMSGVIVNRGLMQCHYNASKAGVIHMSK HHCCCEEEEEEEECCCCHHHHHCCCCEEEEEECCCCHHHHCCCEEEECCCCCCEEEEEHH SMAMEWVGRGIRVNTISPGYTATPMNTRPEMVHQTKLFEEQTPMQRMAGVDEMVGPAIFL HHHHHHHCCCEEEEEECCCCEECCCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHCHHHEE LSDAASFVTGVDLLVDGGFCCW HHHHHHHHHHHHHEECCCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]