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The map label for this gene is glsA

Identifier: 15889160

GI number: 15889160

Start: 1838691

End: 1839620

Strand: Reverse

Name: glsA

Synonym: Atu1859

Alternate gene names: 15889160

Gene position: 1839620-1838691 (Counterclockwise)

Preceding gene: 15889161

Following gene: 159184950

Centisome position: 64.74

GC content: 60.65

Gene sequence:

>930_bases
ATGCAGGACATTCAGGGTATCGTCGATTCCATCTACGACAGCATGCTGCCGCGGCTGGGTGAGGGGAAGGTTGCGGATTA
CATTCCCGAACTCGCCAAGGTCGATCCCAACCAGTTTGGCATCGCCATCACCACCGTCGATGGGACGACCTATACGGCCG
GCAATGCGCTTGTGCCGTTTTCGATCCAGAGTATCTCCAAGGTTTTCATGCTGACGCTGGCGCTCGGCAAGGCGGGCGAA
ACGGTGTGGAACCGGGTGGGGCGCGAACCATCGGGATCGTCTTTCAATTCCATCGTTCAGCTGGAACATGAGCACGGCAT
CCCGCGCAATCCCTTCGTGAATGCCGGCGCCATCGTGGTGACCGATATCGTTCTTTCCGGCCATCAGCCGCGTGAGGCGA
TCGGCGAGCTTCTGCGGTTCGTGCGTTACCTCGCTGACGATGACACGATCAGCATTGACGACACGGTGGCGAAATCCGAG
CAGGCGACGGGTTTCCGCAATTTCGCGCTTGCTAATTTCATGCGGTCCTTCGGCAATCTGCACCATCCCGTGGAACATAC
GCTCGGCGTTTATTTCCATCAGTGTGCACTTTCCATGACCTGCGCGCAGCTGTCGCGGGCTGGCCTCTTCCTTGCCAATC
GCGGCCGTAATCCGCTCTCCGGCCATACCGTCGTGTCGGACCGTCGGGCGCGGCGTATTAATGCGCTGATGCTGACCTGC
GGCCATTATGACGGATCCGGCGATTTCGCCTATCATGTCGGCCTGCCGGGCAAGAGCGGCGTCGGTGGCGGCATCATGGC
GGTGGCGCCGGGCAACGCGTCGATTGCGGTCTGGTCGCCGGGTCTCAACAAGGTCGGCAATTCGGCGCTCGGGTCACAGG
CGCTGGAATTGCTGGCGACCAAAACCGGCTGGTCGGTATTCGGGGCTTGA

Upstream 100 bases:

>100_bases
GCATCTGGTCGTCGAATTCTACTCGCGTTAATCGACGCGTTTCAGTATTGAGAAAGCCGCCCCTCGGGGCGGCTTTTTTG
TTTGCTGGGGAAGGCTTTGC

Downstream 100 bases:

>100_bases
TATTGCCGGCGGATGGGGGCATTGCCTGCATTAAGAACGGCAGTCGTGCCGGAGCGAGTTGATGATGAACATTCTCACCA
AGATCGATGACTTTGTAGAT

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MQDIQGIVDSIYDSMLPRLGEGKVADYIPELAKVDPNQFGIAITTVDGTTYTAGNALVPFSIQSISKVFMLTLALGKAGE
TVWNRVGREPSGSSFNSIVQLEHEHGIPRNPFVNAGAIVVTDIVLSGHQPREAIGELLRFVRYLADDDTISIDDTVAKSE
QATGFRNFALANFMRSFGNLHHPVEHTLGVYFHQCALSMTCAQLSRAGLFLANRGRNPLSGHTVVSDRRARRINALMLTC
GHYDGSGDFAYHVGLPGKSGVGGGIMAVAPGNASIAVWSPGLNKVGNSALGSQALELLATKTGWSVFGA

Sequences:

>Translated_309_residues
MQDIQGIVDSIYDSMLPRLGEGKVADYIPELAKVDPNQFGIAITTVDGTTYTAGNALVPFSIQSISKVFMLTLALGKAGE
TVWNRVGREPSGSSFNSIVQLEHEHGIPRNPFVNAGAIVVTDIVLSGHQPREAIGELLRFVRYLADDDTISIDDTVAKSE
QATGFRNFALANFMRSFGNLHHPVEHTLGVYFHQCALSMTCAQLSRAGLFLANRGRNPLSGHTVVSDRRARRINALMLTC
GHYDGSGDFAYHVGLPGKSGVGGGIMAVAPGNASIAVWSPGLNKVGNSALGSQALELLATKTGWSVFGA
>Mature_309_residues
MQDIQGIVDSIYDSMLPRLGEGKVADYIPELAKVDPNQFGIAITTVDGTTYTAGNALVPFSIQSISKVFMLTLALGKAGE
TVWNRVGREPSGSSFNSIVQLEHEHGIPRNPFVNAGAIVVTDIVLSGHQPREAIGELLRFVRYLADDDTISIDDTVAKSE
QATGFRNFALANFMRSFGNLHHPVEHTLGVYFHQCALSMTCAQLSRAGLFLANRGRNPLSGHTVVSDRRARRINALMLTC
GHYDGSGDFAYHVGLPGKSGVGGGIMAVAPGNASIAVWSPGLNKVGNSALGSQALELLATKTGWSVFGA

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=287, Percent_Identity=39.3728222996516, Blast_Score=207, Evalue=8e-54,
Organism=Homo sapiens, GI20336214, Length=302, Percent_Identity=35.7615894039735, Blast_Score=193, Evalue=2e-49,
Organism=Escherichia coli, GI1787804, Length=305, Percent_Identity=51.8032786885246, Blast_Score=294, Evalue=5e-81,
Organism=Escherichia coli, GI1786693, Length=305, Percent_Identity=39.672131147541, Blast_Score=195, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17507019, Length=293, Percent_Identity=37.542662116041, Blast_Score=197, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI17532727, Length=278, Percent_Identity=37.7697841726619, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI193204073, Length=293, Percent_Identity=35.8361774744027, Blast_Score=183, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI193204075, Length=295, Percent_Identity=36.6101694915254, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281363241, Length=309, Percent_Identity=35.2750809061489, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653162, Length=309, Percent_Identity=35.2750809061489, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281363239, Length=309, Percent_Identity=35.2750809061489, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653164, Length=309, Percent_Identity=35.2750809061489, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24653156, Length=309, Percent_Identity=35.2750809061489, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI116008307, Length=309, Percent_Identity=35.2750809061489, Blast_Score=185, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24653166, Length=309, Percent_Identity=35.2750809061489, Blast_Score=185, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24653158, Length=309, Percent_Identity=35.2750809061489, Blast_Score=185, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA_AGRT5 (Q8UEA1)

Other databases:

- EMBL:   AE007869
- PIR:   A97584
- PIR:   AI2804
- RefSeq:   NP_354841.1
- ProteinModelPortal:   Q8UEA1
- SMR:   Q8UEA1
- STRING:   Q8UEA1
- GeneID:   1133897
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1859
- eggNOG:   COG2066
- HOGENOM:   HBG512335
- OMA:   NALMLTC
- PhylomeDB:   Q8UEA1
- ProtClustDB:   PRK00971
- BioCyc:   ATUM176299-1:ATU1859-MONOMER
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 32927; Mature: 32927

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDIQGIVDSIYDSMLPRLGEGKVADYIPELAKVDPNQFGIAITTVDGTTYTAGNALVPF
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCEEECCCEEECH
SIQSISKVFMLTLALGKAGETVWNRVGREPSGSSFNSIVQLEHEHGIPRNPFVNAGAIVV
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHEEEHHHCCCCCCCCCCCCHHEE
TDIVLSGHQPREAIGELLRFVRYLADDDTISIDDTVAKSEQATGFRNFALANFMRSFGNL
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHCCCHHHHHHHHHHHHHCCC
HHPVEHTLGVYFHQCALSMTCAQLSRAGLFLANRGRNPLSGHTVVSDRRARRINALMLTC
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHEEEEEEE
GHYDGSGDFAYHVGLPGKSGVGGGIMAVAPGNASIAVWSPGLNKVGNSALGSQALELLAT
CCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCEEEEECCCHHHHCCHHHHHHHHHHHHH
KTGWSVFGA
CCCCCCCCC
>Mature Secondary Structure
MQDIQGIVDSIYDSMLPRLGEGKVADYIPELAKVDPNQFGIAITTVDGTTYTAGNALVPF
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCEEECCCEEECH
SIQSISKVFMLTLALGKAGETVWNRVGREPSGSSFNSIVQLEHEHGIPRNPFVNAGAIVV
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHEEEHHHCCCCCCCCCCCCHHEE
TDIVLSGHQPREAIGELLRFVRYLADDDTISIDDTVAKSEQATGFRNFALANFMRSFGNL
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHCCCHHHHHHHHHHHHHCCC
HHPVEHTLGVYFHQCALSMTCAQLSRAGLFLANRGRNPLSGHTVVSDRRARRINALMLTC
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHEEEEEEE
GHYDGSGDFAYHVGLPGKSGVGGGIMAVAPGNASIAVWSPGLNKVGNSALGSQALELLAT
CCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCEEEEECCCHHHHCCHHHHHHHHHHHHH
KTGWSVFGA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194