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The map label for this gene is ubiH [C]

Identifier: 15889098

GI number: 15889098

Start: 1781116

End: 1782324

Strand: Direct

Name: ubiH [C]

Synonym: Atu1794

Alternate gene names: 15889098

Gene position: 1781116-1782324 (Clockwise)

Preceding gene: 15889085

Following gene: 15889107

Centisome position: 62.68

GC content: 62.94

Gene sequence:

>1209_bases
ATGAGACACTTCGATATCGCCATAACAGGTGCGGGACTTGCGGGCCAGATCGCGGCCATCGCACTGGCGCGGGCCGGCCG
CCATGTGGCGCTCATCGCACCTTCAAGCGAGAAGAAGGATCAGCGCACCACGGCGTTGATGGACCAGTCCATTCGCTTCA
TGGACCGTCTCGGCCTCTGGTCACGCATCGCGCCGTCCGCCGCACGCCTTTCCACCATGCAGATCATCGACGGCACCGAC
CGCCTGCTGCGCGCGCCGACCGTGCAGTTCCGCTCCTCTGAAATCGGCCTCGATGCTTTTGGCTGGAATATCCCGAACGA
GGCGCTGCTCGGCGTTCTCAGCGAAGCAGTGGAACAGGAACACAATATTACCCGCCTCGACACAACCGCCGAGACGATCG
ACATCGGCAATGACCGGATTTCGGTCACGATCGCGGATGGTGAAGTGCTTTCCGCCGATTTTCTGATCGGTGCCGACGGC
AGGAAATCGATGGTGCGGGAAGCGGCCGGCATCGGCGTCAAATCCTGGTCCTATCCGCAGACCGCCGTGGTTTTGAATTT
TTCCCACAGCCGTCCGCATGGCAATGTGTCCACGGAATTCCACACACCGACGGGGCCTTTCACCCAGGTTCCCCTGCCGG
ATGACCGCTCCAGCCTCGTCTGGGTCGTCACCCCACAGCAGGCGGAAGAACTGACGGCGCTGCCGCTGGAAACCTTGAGC
CTGAAGGTCGAGGAGCGCATGCAATCCATGCTCGGCGCGGTTACCGTGGAAAACAGCGTGCAGGCATGGCCGCTCTCCTC
CATGACGGCGCACCGCTTCGGCAAGGGCCGCGTCGCCCTGATCGGCGAAGCTGCGCATGGCTTCCCGCCCATCGGCGCGC
AGGGCCTGAACCTCAGCCTGCGCGACATCATTGCACTGACGGAACTGCTTGGCGCCGTCTCCGACCGGCCGATCGCGGCG
GACGCCGGCAGCAGCTTCGACCGCAAACGGCGGGCGGATGTTTATAGCCGCACGCTGAGCGTCGATCTCCTGAACCGCTC
GCTTCTTTCAGATTTTCTTCCGGTGCAGATGGCGCGTGCGGCCGGCCTGCATGTACTCTCCGGCATCGGCACGCTCAGAA
GCATGGTGATGCGCGAAGGCATCGAGCCGGGGCGCGGATTGAAGGCCTTGCCATCATTGCTGTTCGGCAGCTTCAAAAAG
GCTGGATGA

Upstream 100 bases:

>100_bases
CGCAACCAACGAATGTTTGTGTGCGGATGTTCCGGCGCGAAAGTGGATTTACCCGCCCAAAGCCTCTATGATGTTTTGGA
AATAACAATGGATCACGACC

Downstream 100 bases:

>100_bases
AATAAACCACGCCCGTCAGCGTGAAGACCGACAGCACCGTCGAGATCAGGATCGTCGCTGACGCCCTCTCCTGCCAGACG
TGATATTGCTGGCCGATGAC

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MRHFDIAITGAGLAGQIAAIALARAGRHVALIAPSSEKKDQRTTALMDQSIRFMDRLGLWSRIAPSAARLSTMQIIDGTD
RLLRAPTVQFRSSEIGLDAFGWNIPNEALLGVLSEAVEQEHNITRLDTTAETIDIGNDRISVTIADGEVLSADFLIGADG
RKSMVREAAGIGVKSWSYPQTAVVLNFSHSRPHGNVSTEFHTPTGPFTQVPLPDDRSSLVWVVTPQQAEELTALPLETLS
LKVEERMQSMLGAVTVENSVQAWPLSSMTAHRFGKGRVALIGEAAHGFPPIGAQGLNLSLRDIIALTELLGAVSDRPIAA
DAGSSFDRKRRADVYSRTLSVDLLNRSLLSDFLPVQMARAAGLHVLSGIGTLRSMVMREGIEPGRGLKALPSLLFGSFKK
AG

Sequences:

>Translated_402_residues
MRHFDIAITGAGLAGQIAAIALARAGRHVALIAPSSEKKDQRTTALMDQSIRFMDRLGLWSRIAPSAARLSTMQIIDGTD
RLLRAPTVQFRSSEIGLDAFGWNIPNEALLGVLSEAVEQEHNITRLDTTAETIDIGNDRISVTIADGEVLSADFLIGADG
RKSMVREAAGIGVKSWSYPQTAVVLNFSHSRPHGNVSTEFHTPTGPFTQVPLPDDRSSLVWVVTPQQAEELTALPLETLS
LKVEERMQSMLGAVTVENSVQAWPLSSMTAHRFGKGRVALIGEAAHGFPPIGAQGLNLSLRDIIALTELLGAVSDRPIAA
DAGSSFDRKRRADVYSRTLSVDLLNRSLLSDFLPVQMARAAGLHVLSGIGTLRSMVMREGIEPGRGLKALPSLLFGSFKK
AG
>Mature_402_residues
MRHFDIAITGAGLAGQIAAIALARAGRHVALIAPSSEKKDQRTTALMDQSIRFMDRLGLWSRIAPSAARLSTMQIIDGTD
RLLRAPTVQFRSSEIGLDAFGWNIPNEALLGVLSEAVEQEHNITRLDTTAETIDIGNDRISVTIADGEVLSADFLIGADG
RKSMVREAAGIGVKSWSYPQTAVVLNFSHSRPHGNVSTEFHTPTGPFTQVPLPDDRSSLVWVVTPQQAEELTALPLETLS
LKVEERMQSMLGAVTVENSVQAWPLSSMTAHRFGKGRVALIGEAAHGFPPIGAQGLNLSLRDIIALTELLGAVSDRPIAA
DAGSSFDRKRRADVYSRTLSVDLLNRSLLSDFLPVQMARAAGLHVLSGIGTLRSMVMREGIEPGRGLKALPSLLFGSFKK
AG

Specific function: Oxygenase That Introduces The Hydroxyl Group At Carbon Five Of 2-Octaprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol Resulting In The Formation Of 2-Octaprenyl-3-Methyl-5-Hydroxy-6-Methoxy-1,4- Benzoquinol. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=392, Percent_Identity=25, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32967307, Length=331, Percent_Identity=25.6797583081571, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI1786883, Length=390, Percent_Identity=28.2051282051282, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1789273, Length=407, Percent_Identity=25.5528255528256, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789274, Length=380, Percent_Identity=27.6315789473684, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786543, Length=331, Percent_Identity=25.3776435045317, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25146631, Length=440, Percent_Identity=25.4545454545455, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI19920760, Length=437, Percent_Identity=26.5446224256293, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 43229; Mature: 43229

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHFDIAITGAGLAGQIAAIALARAGRHVALIAPSSEKKDQRTTALMDQSIRFMDRLGLW
CCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCHH
SRIAPSAARLSTMQIIDGTDRLLRAPTVQFRSSEIGLDAFGWNIPNEALLGVLSEAVEQE
HHCCCCHHHHEEEEEECCCHHHHHCCCEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHH
HNITRLDTTAETIDIGNDRISVTIADGEVLSADFLIGADGRKSMVREAAGIGVKSWSYPQ
CCCEEECCCHHEEECCCCEEEEEEECCCEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCC
TAVVLNFSHSRPHGNVSTEFHTPTGPFTQVPLPDDRSSLVWVVTPQQAEELTALPLETLS
EEEEEEECCCCCCCCCCCEEECCCCCCEECCCCCCCCCEEEEECCCCHHHHHHCCHHHHH
LKVEERMQSMLGAVTVENSVQAWPLSSMTAHRFGKGRVALIGEAAHGFPPIGAQGLNLSL
HHHHHHHHHHHCEEEECCCCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHH
RDIIALTELLGAVSDRPIAADAGSSFDRKRRADVYSRTLSVDLLNRSLLSDFLPVQMARA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLHVLSGIGTLRSMVMREGIEPGRGLKALPSLLFGSFKKAG
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRHFDIAITGAGLAGQIAAIALARAGRHVALIAPSSEKKDQRTTALMDQSIRFMDRLGLW
CCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCHH
SRIAPSAARLSTMQIIDGTDRLLRAPTVQFRSSEIGLDAFGWNIPNEALLGVLSEAVEQE
HHCCCCHHHHEEEEEECCCHHHHHCCCEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHH
HNITRLDTTAETIDIGNDRISVTIADGEVLSADFLIGADGRKSMVREAAGIGVKSWSYPQ
CCCEEECCCHHEEECCCCEEEEEEECCCEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCC
TAVVLNFSHSRPHGNVSTEFHTPTGPFTQVPLPDDRSSLVWVVTPQQAEELTALPLETLS
EEEEEEECCCCCCCCCCCEEECCCCCCEECCCCCCCCCEEEEECCCCHHHHHHCCHHHHH
LKVEERMQSMLGAVTVENSVQAWPLSSMTAHRFGKGRVALIGEAAHGFPPIGAQGLNLSL
HHHHHHHHHHHCEEEECCCCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHH
RDIIALTELLGAVSDRPIAADAGSSFDRKRRADVYSRTLSVDLLNRSLLSDFLPVQMARA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLHVLSGIGTLRSMVMREGIEPGRGLKALPSLLFGSFKKAG
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydroxylation [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]