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The map label for this gene is ydgK [H]

Identifier: 15889003

GI number: 15889003

Start: 1682347

End: 1683546

Strand: Direct

Name: ydgK [H]

Synonym: Atu1697

Alternate gene names: 15889003

Gene position: 1682347-1683546 (Clockwise)

Preceding gene: 159184875

Following gene: 15889004

Centisome position: 59.2

GC content: 62.92

Gene sequence:

>1200_bases
ATGAAGAGCAGCCGTTTCCTCGACCGAACCACCCCGCCCCATATCATCACGCTTGTGGTCATCGCCGGCGTCGCGGCGCT
GTGCATGAACCTGTTCCTGCCTTCGCTTTCGGCCATGGCGCTCTATTTCGAGATCGATTACGCTGTGATGCAGTTCGCCG
TGTCGGGTTATCTTGCCGCCACCGCCTTGCTGCAACTGGTCATCGGCCCGCTCTCGGATCTTTTCGGCCGCCGTCCTGTG
ATGCTGGCCAGCATCACCATCATGATCGCCGCCACGCTGGTCTGCATGCTGGCGTCCGATATCACCGTCTTCATGATCGG
GCGCGTGGCGCAGGCGGCCGTCGTTTCCGGCTTCGTGCTCGCCCGCGCCATCGTGCGCGACATGGTGCCGATGGAACAGG
CCGCCTCGATGATCGGTTATGTGACCATGGGCATGTCCGTGGTGCCGATGGTTGGCCCAACGGTCGGCGGGTTGCTGAAC
GACTTCTCCGGCTGGCAGTCCAGCTTTGCGCTGCTTGCGCTTCTCGGCGCCGGCATTCTGGTGCTCGCCTGGTTCGATCT
CGGCGAAACCAATCAAAGCAAGTCGGCGAGCTTTTCGCAGCAGTTCCATGCCTGGCCGGAGCTTCTGCGCTCGCCGCTGT
TCTGGGGTTATGCGCTGACCTCGACCTTCTCGTCGGGCATGTTCTTTTCTTTCCTCGGCGGCGCGCCCTTTGTCGGCAGC
GTGCTTTACGGGCTGACACCCGCCATGCTCGGGCTGCAGTTCTTTTTCATGGCCAGCGGTTACATGCTCGGCAATTTCGT
CTCCGGCCGTTATGCCAGCCAGATCGGCATCAGCAGAATGATGCTGTCAGGCAATGTCATCGCCATCGCCGGCATCGTCA
CCGCCATCGCGCTGATAACCGGCGGGGCGGAAAGCGCCTACGCGTTTTTCGTGCCGCTTGCCCTGATCGGCGTTGGAAAC
GGTGTCACGCTGCCCAGCGCCAATGCCGGCATGGTCAGCGTCCAGCCGCATCTGGCAGGCTCCGCCTCCGGGCTGGGCGG
CGCGATGACCATCGGCGGCGGGGCGGCACTTTCGGTGCTCGCCTCCTCGGTCCTGTCCAAGGAGGACGGAACCTGGCCGC
TTCTTCTGGTGATACTGGCGACCGGCCTTGTCGCCCTTCTCACCACCTATGTCGTAAGGCTGCAGGAACAGCGGCAATGA

Upstream 100 bases:

>100_bases
CAAATGGCCAAGCGCGCGGCCGCGACACCCACAGCCGCAACCACGGTACGACCGGCTTCCGTTACGAAAGCTACCGTAAC
GGAAGAGGCGGGAGAATAAC

Downstream 100 bases:

>100_bases
TCGCCCCTCCCCGAAAAATACCCGGTCTCGTGCCCCCTGGTCTCATATTGGCCGGCGGGCTGTCGCGGCGCATGGGCAGC
AACAAGGCGATGGTGACGCT

Product: MFS permease

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKSSRFLDRTTPPHIITLVVIAGVAALCMNLFLPSLSAMALYFEIDYAVMQFAVSGYLAATALLQLVIGPLSDLFGRRPV
MLASITIMIAATLVCMLASDITVFMIGRVAQAAVVSGFVLARAIVRDMVPMEQAASMIGYVTMGMSVVPMVGPTVGGLLN
DFSGWQSSFALLALLGAGILVLAWFDLGETNQSKSASFSQQFHAWPELLRSPLFWGYALTSTFSSGMFFSFLGGAPFVGS
VLYGLTPAMLGLQFFFMASGYMLGNFVSGRYASQIGISRMMLSGNVIAIAGIVTAIALITGGAESAYAFFVPLALIGVGN
GVTLPSANAGMVSVQPHLAGSASGLGGAMTIGGGAALSVLASSVLSKEDGTWPLLLVILATGLVALLTTYVVRLQEQRQ

Sequences:

>Translated_399_residues
MKSSRFLDRTTPPHIITLVVIAGVAALCMNLFLPSLSAMALYFEIDYAVMQFAVSGYLAATALLQLVIGPLSDLFGRRPV
MLASITIMIAATLVCMLASDITVFMIGRVAQAAVVSGFVLARAIVRDMVPMEQAASMIGYVTMGMSVVPMVGPTVGGLLN
DFSGWQSSFALLALLGAGILVLAWFDLGETNQSKSASFSQQFHAWPELLRSPLFWGYALTSTFSSGMFFSFLGGAPFVGS
VLYGLTPAMLGLQFFFMASGYMLGNFVSGRYASQIGISRMMLSGNVIAIAGIVTAIALITGGAESAYAFFVPLALIGVGN
GVTLPSANAGMVSVQPHLAGSASGLGGAMTIGGGAALSVLASSVLSKEDGTWPLLLVILATGLVALLTTYVVRLQEQRQ
>Mature_399_residues
MKSSRFLDRTTPPHIITLVVIAGVAALCMNLFLPSLSAMALYFEIDYAVMQFAVSGYLAATALLQLVIGPLSDLFGRRPV
MLASITIMIAATLVCMLASDITVFMIGRVAQAAVVSGFVLARAIVRDMVPMEQAASMIGYVTMGMSVVPMVGPTVGGLLN
DFSGWQSSFALLALLGAGILVLAWFDLGETNQSKSASFSQQFHAWPELLRSPLFWGYALTSTFSSGMFFSFLGGAPFVGS
VLYGLTPAMLGLQFFFMASGYMLGNFVSGRYASQIGISRMMLSGNVIAIAGIVTAIALITGGAESAYAFFVPLALIGVGN
GVTLPSANAGMVSVQPHLAGSASGLGGAMTIGGGAALSVLASSVLSKEDGTWPLLLVILATGLVALLTTYVVRLQEQRQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=356, Percent_Identity=27.8089887640449, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1788509, Length=395, Percent_Identity=28.6075949367089, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082312, Length=327, Percent_Identity=26.9113149847095, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790146, Length=209, Percent_Identity=28.2296650717703, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790794, Length=178, Percent_Identity=28.0898876404494, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41668; Mature: 41668

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSSRFLDRTTPPHIITLVVIAGVAALCMNLFLPSLSAMALYFEIDYAVMQFAVSGYLAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALLQLVIGPLSDLFGRRPVMLASITIMIAATLVCMLASDITVFMIGRVAQAAVVSGFVL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
ARAIVRDMVPMEQAASMIGYVTMGMSVVPMVGPTVGGLLNDFSGWQSSFALLALLGAGIL
HHHHHHHHCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAWFDLGETNQSKSASFSQQFHAWPELLRSPLFWGYALTSTFSSGMFFSFLGGAPFVGS
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHCCCHHHHH
VLYGLTPAMLGLQFFFMASGYMLGNFVSGRYASQIGISRMMLSGNVIAIAGIVTAIALIT
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GGAESAYAFFVPLALIGVGNGVTLPSANAGMVSVQPHLAGSASGLGGAMTIGGGAALSVL
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCHHHHHHH
ASSVLSKEDGTWPLLLVILATGLVALLTTYVVRLQEQRQ
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9202461 [H]