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The map label for this gene is gph [H]

Identifier: 15888796

GI number: 15888796

Start: 1466678

End: 1467346

Strand: Direct

Name: gph [H]

Synonym: Atu1472

Alternate gene names: 15888796

Gene position: 1466678-1467346 (Clockwise)

Preceding gene: 159184771

Following gene: 15888797

Centisome position: 51.61

GC content: 58.59

Gene sequence:

>669_bases
ATGAAACTCGTCCTTTTCGATTGCGACGGCACACTGGTGGACAGCGCCGGCCTGATCCATGCCGTCATGTCCGAGACCTT
TGCCGATTTTGGAAAACCGCGGCCTGATATATCCGAGACCAAGGCGATCATCGGGCTGACGCTGGATATCGCCATCGCCC
GCATGCTGGGCAGGGCCCATGTGGACGACGAAGCGGCGGCCATGGCGCTGCGCTATAAAGAGAACTATCATCCGCTGAGA
GAACGTTTCGAAAACGCAACTCCGCTTTTCGATGGCATAGCCTCTTTGATCGATATGCTGTCGAAGCGGGATGACGTGCT
GATCGGCGCTGTCACCGGCAAGGGCCGGCGTGGGCTCACCCAAATTCTGGAAACCCATGGCTTTGCCGATCATTTCATCG
TTTCGCGCACGGCGGATGACTGCCCCTCCAAGCCGCACCCGGCAATGGTGATGGAGTGCTGCCACGAAACCGGCATGGTT
CCGGCCGATACTATCGTCATTGGTGACGCGATCTATGACATGCAGATGGCGAAAGCGGCTGGTGCAAAAGCCATCGGCGT
CGCCTGGGGTTATGCCTCGGTCGAAGACCTCTGGAAGGCGGGCGCCGATGCGGTGGTCAACCATCCGAACGACATTCCGG
CCTATGTTCCGGCCGACATTACCGAATGA

Upstream 100 bases:

>100_bases
CCGGCTTCGCGTCAGCGCACCCTTGCCGCCGCACATGGTACAGACCTGGAACCTGCTCGGCCTCGACGTGGCCGATGGCG
ATAGGGAAGACTGACAACAG

Downstream 100 bases:

>100_bases
CCTTTTCTATCCGACTGACGAGGATGTGCCATGCGTGATCTCCTGAACGACCTTTCAGAGGGCCTCAGCCACCCCGACCC
GATCCTGCGCGCGCAGATCC

Product: hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKLVLFDCDGTLVDSAGLIHAVMSETFADFGKPRPDISETKAIIGLTLDIAIARMLGRAHVDDEAAAMALRYKENYHPLR
ERFENATPLFDGIASLIDMLSKRDDVLIGAVTGKGRRGLTQILETHGFADHFIVSRTADDCPSKPHPAMVMECCHETGMV
PADTIVIGDAIYDMQMAKAAGAKAIGVAWGYASVEDLWKAGADAVVNHPNDIPAYVPADITE

Sequences:

>Translated_222_residues
MKLVLFDCDGTLVDSAGLIHAVMSETFADFGKPRPDISETKAIIGLTLDIAIARMLGRAHVDDEAAAMALRYKENYHPLR
ERFENATPLFDGIASLIDMLSKRDDVLIGAVTGKGRRGLTQILETHGFADHFIVSRTADDCPSKPHPAMVMECCHETGMV
PADTIVIGDAIYDMQMAKAAGAKAIGVAWGYASVEDLWKAGADAVVNHPNDIPAYVPADITE
>Mature_222_residues
MKLVLFDCDGTLVDSAGLIHAVMSETFADFGKPRPDISETKAIIGLTLDIAIARMLGRAHVDDEAAAMALRYKENYHPLR
ERFENATPLFDGIASLIDMLSKRDDVLIGAVTGKGRRGLTQILETHGFADHFIVSRTADDCPSKPHPAMVMECCHETGMV
PADTIVIGDAIYDMQMAKAAGAKAIGVAWGYASVEDLWKAGADAVVNHPNDIPAYVPADITE

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=235, Percent_Identity=30.6382978723404, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR000150
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23940; Mature: 23940

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVLFDCDGTLVDSAGLIHAVMSETFADFGKPRPDISETKAIIGLTLDIAIARMLGRAH
CEEEEEECCCCEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
VDDEAAAMALRYKENYHPLRERFENATPLFDGIASLIDMLSKRDDVLIGAVTGKGRRGLT
CCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHH
QILETHGFADHFIVSRTADDCPSKPHPAMVMECCHETGMVPADTIVIGDAIYDMQMAKAA
HHHHHCCCHHHHEEECCCCCCCCCCCHHHHHHHHHHCCCCCCHHEEECHHHHHHHHHHHC
GAKAIGVAWGYASVEDLWKAGADAVVNHPNDIPAYVPADITE
CCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLVLFDCDGTLVDSAGLIHAVMSETFADFGKPRPDISETKAIIGLTLDIAIARMLGRAH
CEEEEEECCCCEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
VDDEAAAMALRYKENYHPLRERFENATPLFDGIASLIDMLSKRDDVLIGAVTGKGRRGLT
CCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHH
QILETHGFADHFIVSRTADDCPSKPHPAMVMECCHETGMVPADTIVIGDAIYDMQMAKAA
HHHHHCCCHHHHEEECCCCCCCCCCCHHHHHHHHHHCCCCCCHHEEECHHHHHHHHHHHC
GAKAIGVAWGYASVEDLWKAGADAVVNHPNDIPAYVPADITE
CCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]