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The map label for this gene is nouD

Identifier: 15888601

GI number: 15888601

Start: 1258211

End: 1259401

Strand: Direct

Name: nouD

Synonym: Atu1272

Alternate gene names: 15888601

Gene position: 1258211-1259401 (Clockwise)

Preceding gene: 15888600

Following gene: 15888602

Centisome position: 44.28

GC content: 59.61

Gene sequence:

>1191_bases
ATGACTGAGCATAACGTCCGCAATTTCACGATCAACTTCGGTCCGGAACACCCTTCCGCGCACGGCGTGCTGCGTCTGGT
TCTGGAACTGGACGGCGAAATCGTCGAGCGTGTCGATCCGCATATCGGTCTTCTGCATCGCGGCACCGAAAAGCTGATCG
AGACCAAGACCTATCTCCAGGCCGTTCCTTACTTCGACCGCCTCGATTACGTCGCGCCGATGAACCAGGAACACGCTTTC
GCGCTTGCCGTCGAAAAGCTGCTTGGCCTTGAAATCCCGATGCGCGGCCAGCTGATCCGCGTTCTCTATTCGGAAATCGG
CCGCATCCTGTCGCACATCATGAACGTGACGACGCAGGCCATGGACGTCGGCGCGATGACGCCGCCCGTCTGGGGCTTCG
AAGAGCGCGAAAAGCTGATGGTGTTCTATGAGCGCGCCTGCGGCGCCCGCATGCACTCGGCTTATGTCCGTCCGGGCGGC
GTGCACCAGGATCTGCCGCCGGAACTGGTGGACGATATCGGCAAGTGGTGCGATCCGTTCCTCACCGTTCTCGACAACAT
CGAAGGTCTTCTGACCGACAACCGTATCTACAAGCAGCGTAACGTCGATATCGGCGTCGTGTCGCTGGAAGATGCGTTTG
CCTGGGGCTTCACGGGCGTGATGGTGCGCGGTTCGGGCGCTGCCTGGGATCTGCGCCGTTCGCAGCCCTATGAATGTTAT
TCCGATCTGGAATTCGACATTCCCGTTGGCAAGAACGGCGACTGCTATGACCGTTACCTGATCCGCATGCAGGAAATGCG
CGAATCGGTAAAGATCATGAAGCAGTGCGTCGATCGTCTGTCCGGCAAACACCGCATCGGCCCGGTCTCTTCGCTTGACG
GCAAGGTTGTTCCGCCCAAGCGTGGCGAAATGAAGCGTTCGATGGAAGCTCTGATCCATCACTTCAAGCTCTACACCGAA
GGTTACCACGTTCCGGCCGGCGAAGTTTACGCCGCCGTCGAGGCGCCGAAGGGCGAGTTCGGCGTTTACGTGGTTGCCGA
CGGTTCCAACAAGCCCTACCGCTGCAAGATCCGCGCGCCGGGTTATGCACACCTGCAGGCGATGGATTTCCTGTGCAAGG
GCCATCAGCTTGCCGACGTTACAGCCGTGCTCGGCTCTCTCGACATCGTGTTCGGGGAGGTCGACCGCTGA

Upstream 100 bases:

>100_bases
TTCACGGATGAAAAGCCTTCGAGCTATTCGTTCGCGCAGACCACGCAAAACATGACCGGCCCCGAATTCATCGCCATGAT
CACCTCGGCGGAGCACTAGA

Downstream 100 bases:

>100_bases
TGCGTCTGCCGCTGGCCATACCGGCTTTTCTCGCTGCGATGTCCACCCCCGTTCTCGCCCAGACGGCGACGGACGAGGGC
GGTGTATCGCTGTCGGGCGG

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTEHNVRNFTINFGPEHPSAHGVLRLVLELDGEIVERVDPHIGLLHRGTEKLIETKTYLQAVPYFDRLDYVAPMNQEHAF
ALAVEKLLGLEIPMRGQLIRVLYSEIGRILSHIMNVTTQAMDVGAMTPPVWGFEEREKLMVFYERACGARMHSAYVRPGG
VHQDLPPELVDDIGKWCDPFLTVLDNIEGLLTDNRIYKQRNVDIGVVSLEDAFAWGFTGVMVRGSGAAWDLRRSQPYECY
SDLEFDIPVGKNGDCYDRYLIRMQEMRESVKIMKQCVDRLSGKHRIGPVSSLDGKVVPPKRGEMKRSMEALIHHFKLYTE
GYHVPAGEVYAAVEAPKGEFGVYVVADGSNKPYRCKIRAPGYAHLQAMDFLCKGHQLADVTAVLGSLDIVFGEVDR

Sequences:

>Translated_396_residues
MTEHNVRNFTINFGPEHPSAHGVLRLVLELDGEIVERVDPHIGLLHRGTEKLIETKTYLQAVPYFDRLDYVAPMNQEHAF
ALAVEKLLGLEIPMRGQLIRVLYSEIGRILSHIMNVTTQAMDVGAMTPPVWGFEEREKLMVFYERACGARMHSAYVRPGG
VHQDLPPELVDDIGKWCDPFLTVLDNIEGLLTDNRIYKQRNVDIGVVSLEDAFAWGFTGVMVRGSGAAWDLRRSQPYECY
SDLEFDIPVGKNGDCYDRYLIRMQEMRESVKIMKQCVDRLSGKHRIGPVSSLDGKVVPPKRGEMKRSMEALIHHFKLYTE
GYHVPAGEVYAAVEAPKGEFGVYVVADGSNKPYRCKIRAPGYAHLQAMDFLCKGHQLADVTAVLGSLDIVFGEVDR
>Mature_395_residues
TEHNVRNFTINFGPEHPSAHGVLRLVLELDGEIVERVDPHIGLLHRGTEKLIETKTYLQAVPYFDRLDYVAPMNQEHAFA
LAVEKLLGLEIPMRGQLIRVLYSEIGRILSHIMNVTTQAMDVGAMTPPVWGFEEREKLMVFYERACGARMHSAYVRPGGV
HQDLPPELVDDIGKWCDPFLTVLDNIEGLLTDNRIYKQRNVDIGVVSLEDAFAWGFTGVMVRGSGAAWDLRRSQPYECYS
DLEFDIPVGKNGDCYDRYLIRMQEMRESVKIMKQCVDRLSGKHRIGPVSSLDGKVVPPKRGEMKRSMEALIHHFKLYTEG
YHVPAGEVYAAVEAPKGEFGVYVVADGSNKPYRCKIRAPGYAHLQAMDFLCKGHQLADVTAVLGSLDIVFGEVDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=391, Percent_Identity=64.4501278772378, Blast_Score=529, Evalue=1e-150,
Organism=Homo sapiens, GI260898743, Length=385, Percent_Identity=63.6363636363636, Blast_Score=514, Evalue=1e-146,
Organism=Escherichia coli, GI145693162, Length=387, Percent_Identity=37.7260981912145, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1789076, Length=392, Percent_Identity=25.2551020408163, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788832, Length=398, Percent_Identity=24.6231155778894, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17555284, Length=394, Percent_Identity=60.6598984771574, Blast_Score=516, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17568379, Length=394, Percent_Identity=60.4060913705584, Blast_Score=511, Evalue=1e-145,
Organism=Drosophila melanogaster, GI24638644, Length=394, Percent_Identity=61.6751269035533, Blast_Score=533, Evalue=1e-152,
Organism=Drosophila melanogaster, GI221459469, Length=394, Percent_Identity=55.8375634517767, Blast_Score=475, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOD_AGRT5 (A9CJA9)

Other databases:

- EMBL:   AE007869
- PIR:   AH2732
- PIR:   B97514
- RefSeq:   NP_354282.1
- ProteinModelPortal:   A9CJA9
- SMR:   A9CJA9
- STRING:   A9CJA9
- GeneID:   1133310
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1272
- eggNOG:   COG0649
- HOGENOM:   HBG459705
- OMA:   IFYERAC
- PhylomeDB:   A9CJA9
- ProtClustDB:   PRK06075
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 44650; Mature: 44519

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00535 COMPLEX1_49K; PS00503 PECTINESTERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHNVRNFTINFGPEHPSAHGVLRLVLELDGEIVERVDPHIGLLHRGTEKLIETKTYLQ
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHCHHHHHHCCCCHHHHHCCHHHHHHHHHHHH
AVPYFDRLDYVAPMNQEHAFALAVEKLLGLEIPMRGQLIRVLYSEIGRILSHIMNVTTQA
HCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MDVGAMTPPVWGFEEREKLMVFYERACGARMHSAYVRPGGVHQDLPPELVDDIGKWCDPF
HHCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
LTVLDNIEGLLTDNRIYKQRNVDIGVVSLEDAFAWGFTGVMVRGSGAAWDLRRSQPYECY
HHHHHHHHHHHCCCHHHHHCCCCEEEEEECCHHHHCCEEEEEECCCCEEECCCCCCCCHH
SDLEFDIPVGKNGDCYDRYLIRMQEMRESVKIMKQCVDRLSGKHRIGPVSSLDGKVVPPK
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RGEMKRSMEALIHHFKLYTEGYHVPAGEVYAAVEAPKGEFGVYVVADGSNKPYRCKIRAP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEEECC
GYAHLQAMDFLCKGHQLADVTAVLGSLDIVFGEVDR
CCHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCCC
>Mature Secondary Structure 
TEHNVRNFTINFGPEHPSAHGVLRLVLELDGEIVERVDPHIGLLHRGTEKLIETKTYLQ
CCCCCEEEEEEECCCCCCHHHHHHHHHHHCHHHHHHCCCCHHHHHCCHHHHHHHHHHHH
AVPYFDRLDYVAPMNQEHAFALAVEKLLGLEIPMRGQLIRVLYSEIGRILSHIMNVTTQA
HCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MDVGAMTPPVWGFEEREKLMVFYERACGARMHSAYVRPGGVHQDLPPELVDDIGKWCDPF
HHCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
LTVLDNIEGLLTDNRIYKQRNVDIGVVSLEDAFAWGFTGVMVRGSGAAWDLRRSQPYECY
HHHHHHHHHHHCCCHHHHHCCCCEEEEEECCHHHHCCEEEEEECCCCEEECCCCCCCCHH
SDLEFDIPVGKNGDCYDRYLIRMQEMRESVKIMKQCVDRLSGKHRIGPVSSLDGKVVPPK
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RGEMKRSMEALIHHFKLYTEGYHVPAGEVYAAVEAPKGEFGVYVVADGSNKPYRCKIRAP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEEECC
GYAHLQAMDFLCKGHQLADVTAVLGSLDIVFGEVDR
CCHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743194; 11743193