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The map label for this gene is nuoC

Identifier: 15888599

GI number: 15888599

Start: 1257182

End: 1257784

Strand: Direct

Name: nuoC

Synonym: Atu1270

Alternate gene names: 15888599

Gene position: 1257182-1257784 (Clockwise)

Preceding gene: 15888598

Following gene: 15888600

Centisome position: 44.24

GC content: 55.89

Gene sequence:

>603_bases
ATGAGCGAAGCTCTCAATGATCTTGCTGCTTACGTCAAGGAAGCGCGTGGTTCTCTCGTGGTATCGGCCGATATCGCCTA
TGGCGAGCTGACGCTGAATACCACGCCTGAAAACGTGATCGCGCTTTTGACCTTCCTGCGCGACGACGTGCAGTGCGGCT
TCGTCAACATCATCGATATTTGCGGCGTAGACTGGCCGCAGCGCGAGAAGCGTTTCGATGTCGTCTACCATCTGCTGTCG
CCACGCCAGAACCTGCGCGTGCGCATCAAGCTGCAGGTCGCGGAAGACGAAGGCGTGCCTTCTTCGACACCTGTTTACAT
GGGCGCGGAATGGTTCGAGCGCGAAGCCTGGGATATGTATGGCATTCCTTTCGAGGGCCACAAGGACCTGCGCCGCATCC
TCACGGATTACGGTTTCGAAGGCCACCCGCTGCGCAAGGATTTTCCGGTTACCGGCTTTGTGGAAGTGCGTTACGATGAC
GTGCTGAAGCGGGTTCTTTATGAACCGGTCGAATTGAAGCAGGAATTCCGCAATTTCGATTTCCTTTCCCCGTGGGAAGG
AACGGAATATGTTCTCCCGGGTGACGAAAAGGCCAAGCAATGA

Upstream 100 bases:

>100_bases
CCCCACGGCGGAGGCGCTGCTTTACGGCGTGCTTCTGCTGCAAAAGAAAATTCGTCGTACCGGTACGATCGAGCGCTAAG
GGCAAAGGACGGATTTCGGA

Downstream 100 bases:

>100_bases
GCGAAGCCCCCGCGACAGAGCATGGACAATGTCTTTGCGGCGCCGTTGGCTTCACAGCCACGCTCGGTGCCCGCGAATTC
GGCGTCTGCCATTGCTCCAT

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSEALNDLAAYVKEARGSLVVSADIAYGELTLNTTPENVIALLTFLRDDVQCGFVNIIDICGVDWPQREKRFDVVYHLLS
PRQNLRVRIKLQVAEDEGVPSSTPVYMGAEWFEREAWDMYGIPFEGHKDLRRILTDYGFEGHPLRKDFPVTGFVEVRYDD
VLKRVLYEPVELKQEFRNFDFLSPWEGTEYVLPGDEKAKQ

Sequences:

>Translated_200_residues
MSEALNDLAAYVKEARGSLVVSADIAYGELTLNTTPENVIALLTFLRDDVQCGFVNIIDICGVDWPQREKRFDVVYHLLS
PRQNLRVRIKLQVAEDEGVPSSTPVYMGAEWFEREAWDMYGIPFEGHKDLRRILTDYGFEGHPLRKDFPVTGFVEVRYDD
VLKRVLYEPVELKQEFRNFDFLSPWEGTEYVLPGDEKAKQ
>Mature_199_residues
SEALNDLAAYVKEARGSLVVSADIAYGELTLNTTPENVIALLTFLRDDVQCGFVNIIDICGVDWPQREKRFDVVYHLLSP
RQNLRVRIKLQVAEDEGVPSSTPVYMGAEWFEREAWDMYGIPFEGHKDLRRILTDYGFEGHPLRKDFPVTGFVEVRYDDV
LKRVLYEPVELKQEFRNFDFLSPWEGTEYVLPGDEKAKQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=184, Percent_Identity=50.5434782608696, Blast_Score=192, Evalue=1e-49,
Organism=Escherichia coli, GI145693162, Length=146, Percent_Identity=34.2465753424658, Blast_Score=89, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32563621, Length=185, Percent_Identity=50.2702702702703, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI71990788, Length=185, Percent_Identity=50.2702702702703, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24656494, Length=183, Percent_Identity=52.4590163934426, Blast_Score=195, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_AGRT5 (A9CJB1)

Other databases:

- EMBL:   AE007869
- PIR:   AF2732
- PIR:   H97513
- RefSeq:   NP_354280.1
- ProteinModelPortal:   A9CJB1
- SMR:   A9CJB1
- STRING:   A9CJB1
- GeneID:   1133308
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1270
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   PRK06074
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 23111; Mature: 22980

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEALNDLAAYVKEARGSLVVSADIAYGELTLNTTPENVIALLTFLRDDVQCGFVNIIDI
CCHHHHHHHHHHHHHCCCEEEEEECEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHH
CGVDWPQREKRFDVVYHLLSPRQNLRVRIKLQVAEDEGVPSSTPVYMGAEWFEREAWDMY
HCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEECHHHHHHCCCCCC
GIPFEGHKDLRRILTDYGFEGHPLRKDFPVTGFVEVRYDDVLKRVLYEPVELKQEFRNFD
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCHHHHHHHHHCCC
FLSPWEGTEYVLPGDEKAKQ
CCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
SEALNDLAAYVKEARGSLVVSADIAYGELTLNTTPENVIALLTFLRDDVQCGFVNIIDI
CHHHHHHHHHHHHHCCCEEEEEECEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHH
CGVDWPQREKRFDVVYHLLSPRQNLRVRIKLQVAEDEGVPSSTPVYMGAEWFEREAWDMY
HCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEECHHHHHHCCCCCC
GIPFEGHKDLRRILTDYGFEGHPLRKDFPVTGFVEVRYDDVLKRVLYEPVELKQEFRNFD
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCHHHHHHHHHCCC
FLSPWEGTEYVLPGDEKAKQ
CCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743194; 11743193