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The map label for this gene is speB [H]

Identifier: 15888576

GI number: 15888576

Start: 1234949

End: 1235902

Strand: Reverse

Name: speB [H]

Synonym: Atu1245

Alternate gene names: 15888576

Gene position: 1235902-1234949 (Counterclockwise)

Preceding gene: 15888577

Following gene: 159184681

Centisome position: 43.49

GC content: 60.59

Gene sequence:

>954_bases
ATGCCGGCCAAAACAATCGACCATGCCTTTACCGCGACAACGCTGACTTCGGCCGCAACCGACCCAACCCATGCGGGCGT
CCTCTCCTTCATGCGACGCAAGTATACAAAGAACCTCAAGGGCGTTTCGACGGCGATCTGGGGTATTCCGTTTGACGCGG
CAACCTCCAACCGGCCGGGTGCGCGCTTCGGGCCGCAGGCGATCCGCCGCGCGTCCGCGATCTTCGACAATGATCCGCAA
TATCCCTTCGCGCGCGATCTTTTCGCCCATATGCCGACCATCGATTATGGCGACTGCCTGCTCGACTACGGCAACCATTG
GAAAACGCCTGACACGATCGAAAAGGAAGCGCGCAGGATCATCTCCAAGACGGATTATCTGCTGACGCTCGGCGGTGATC
ACTTCATCACCTGGCCATTGCTGAAAGCGCATGTGGCCAAGCACGGGCGTCTGGCGCTAGTGCAGTTCGACGCGCATCAG
GATACATGGTTCGATGATGGCAAGCGCATCGACCACGGCTCCTTCGTGGCGCGCGCCGTGCGCGACGGACTGATAGATCC
TGACCGTTCGATCCAGATCGGTATTCGCACCCATGCGCCCGACGATTTCGGCATCCGTATTCTCCACGGTTACGAGGTGG
AGGATATGCGGGCGAGCGATATTGCCTCGCTGATCGTCAAGCACACGGGCGGCATGCCTGCTTACCTGACCTTCGATATC
GATTGCCTCGATCCCGCTTTCGCACCGGGAACCGGCACACCCGTCGCCGGCGGACCGACCAGCGCCAAGATTCTCTCGGT
TCTGCGCGGGCTCGGCCAGCTTGATATTCGCGGCTCTGACGTGGTGGAGGTGGCACCCGCTTACGATCATGCGGATATTA
CCGCCATTGCCGGGGCCACCGTTGCAATGTATATGCTTGGCCTGCGTGCCGAACGGCTGGCGAAGGCTGGCTGA

Upstream 100 bases:

>100_bases
AAAAGGCGGGGCTTCGGCTCCGCCTTTTTTCATGACCCTTCTCCCTTGTTTTTTCGGCGAGAAGGCAGCACCTTCAGCGC
AAAACGCGATGGGGTGACAT

Downstream 100 bases:

>100_bases
CGAATAAAACGGCACTTGCCGAACTGATTCCGAATACCCTCGCAACCCTTTGAAAAGGCAGGACAAGGACATGACAGCGA
AGATCTTCATCGATGGCGAA

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MPAKTIDHAFTATTLTSAATDPTHAGVLSFMRRKYTKNLKGVSTAIWGIPFDAATSNRPGARFGPQAIRRASAIFDNDPQ
YPFARDLFAHMPTIDYGDCLLDYGNHWKTPDTIEKEARRIISKTDYLLTLGGDHFITWPLLKAHVAKHGRLALVQFDAHQ
DTWFDDGKRIDHGSFVARAVRDGLIDPDRSIQIGIRTHAPDDFGIRILHGYEVEDMRASDIASLIVKHTGGMPAYLTFDI
DCLDPAFAPGTGTPVAGGPTSAKILSVLRGLGQLDIRGSDVVEVAPAYDHADITAIAGATVAMYMLGLRAERLAKAG

Sequences:

>Translated_317_residues
MPAKTIDHAFTATTLTSAATDPTHAGVLSFMRRKYTKNLKGVSTAIWGIPFDAATSNRPGARFGPQAIRRASAIFDNDPQ
YPFARDLFAHMPTIDYGDCLLDYGNHWKTPDTIEKEARRIISKTDYLLTLGGDHFITWPLLKAHVAKHGRLALVQFDAHQ
DTWFDDGKRIDHGSFVARAVRDGLIDPDRSIQIGIRTHAPDDFGIRILHGYEVEDMRASDIASLIVKHTGGMPAYLTFDI
DCLDPAFAPGTGTPVAGGPTSAKILSVLRGLGQLDIRGSDVVEVAPAYDHADITAIAGATVAMYMLGLRAERLAKAG
>Mature_316_residues
PAKTIDHAFTATTLTSAATDPTHAGVLSFMRRKYTKNLKGVSTAIWGIPFDAATSNRPGARFGPQAIRRASAIFDNDPQY
PFARDLFAHMPTIDYGDCLLDYGNHWKTPDTIEKEARRIISKTDYLLTLGGDHFITWPLLKAHVAKHGRLALVQFDAHQD
TWFDDGKRIDHGSFVARAVRDGLIDPDRSIQIGIRTHAPDDFGIRILHGYEVEDMRASDIASLIVKHTGGMPAYLTFDID
CLDPAFAPGTGTPVAGGPTSAKILSVLRGLGQLDIRGSDVVEVAPAYDHADITAIAGATVAMYMLGLRAERLAKAG

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=294, Percent_Identity=38.4353741496599, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI10947139, Length=299, Percent_Identity=24.7491638795987, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789306, Length=268, Percent_Identity=45.8955223880597, Blast_Score=229, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 34495; Mature: 34363

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAKTIDHAFTATTLTSAATDPTHAGVLSFMRRKYTKNLKGVSTAIWGIPFDAATSNRPG
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCC
ARFGPQAIRRASAIFDNDPQYPFARDLFAHMPTIDYGDCLLDYGNHWKTPDTIEKEARRI
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHH
ISKTDYLLTLGGDHFITWPLLKAHVAKHGRLALVQFDAHQDTWFDDGKRIDHGSFVARAV
HHCCCEEEEECCCCEEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
RDGLIDPDRSIQIGIRTHAPDDFGIRILHGYEVEDMRASDIASLIVKHTGGMPAYLTFDI
HHCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEEE
DCLDPAFAPGTGTPVAGGPTSAKILSVLRGLGQLDIRGSDVVEVAPAYDHADITAIAGAT
EECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHH
VAMYMLGLRAERLAKAG
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PAKTIDHAFTATTLTSAATDPTHAGVLSFMRRKYTKNLKGVSTAIWGIPFDAATSNRPG
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCC
ARFGPQAIRRASAIFDNDPQYPFARDLFAHMPTIDYGDCLLDYGNHWKTPDTIEKEARRI
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHH
ISKTDYLLTLGGDHFITWPLLKAHVAKHGRLALVQFDAHQDTWFDDGKRIDHGSFVARAV
HHCCCEEEEECCCCEEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
RDGLIDPDRSIQIGIRTHAPDDFGIRILHGYEVEDMRASDIASLIVKHTGGMPAYLTFDI
HHCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEEE
DCLDPAFAPGTGTPVAGGPTSAKILSVLRGLGQLDIRGSDVVEVAPAYDHADITAIAGAT
EECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHH
VAMYMLGLRAERLAKAG
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]