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The map label for this gene is catB2 [H]

Identifier: 15888483

GI number: 15888483

Start: 1136724

End: 1137356

Strand: Reverse

Name: catB2 [H]

Synonym: Atu1146

Alternate gene names: 15888483

Gene position: 1137356-1136724 (Counterclockwise)

Preceding gene: 159185420

Following gene: 159184635

Centisome position: 40.03

GC content: 59.87

Gene sequence:

>633_bases
ATGGACTCGACCGCACAGATCAAGCGCCCGAAACTCGCAGAGACCGTCATTCATGCGACGGCGAGCATAAGAGATTCGAA
CATTGGCAGATGCTGCGAGGTCCTGGCTGACACCTCGCTGCACAATGTTGAACTTGGGAATTACTCCTATCTCGGGCCGC
GCTGCATGGTGGGTGATGCGATAATCGGAAAGTTCTGCGCCATTGCTGCGGAGGTCAGGATAGGCGCTCCGAACCACCCG
ATGGACCGGCCATCCACGCATCGTTTCAGCTACTGCCCGGAATATTACGCTGCCGATGCGGTGCGCGACGACGCCTTCTT
CGCCCAGCGAAAGCAGGATCGCGCCATCATCGGTCACGATGTCTGGATCGGCCACGGGGTCATCGTCTTGCCGGGTGTAA
CGGTTGGAGACGGCGCGGTTCTTGCCGCCGGTGCCGTTGTCACCAAAGATGTGCCGCCCTACACCATCGTCGGCGGCGTT
CCCGCAAAAATCATTCGCGAGCGCTTTTCACGATCCATCGCGGAGAAGCTTGCCGCCATCGCCTGGTGGGACTGGCCATT
CGAGACGATCATGGCGCGGCTCGCCGACTTCCAGTCAGGAGATATCGAAGCCTTTTGCGAGCGCTGGTCGTAG

Upstream 100 bases:

>100_bases
CACTTGAAAAAAATTCCTGTTACTGCCGGAATGCTTCGCCATCCCACGTCACAGGCTCTTCATCATCCCCGGTTAAGCAG
GCGCAAAACCGGAGACTGGA

Downstream 100 bases:

>100_bases
CCAGCGCCGCAAAACAGGGCATTGCCGTTCGTTACTCAAACACAAAGGCCAGCCGCTTGCCCGTCAGCTTCGCCAACTGT
TGCAAACGGCCATCCAGCCG

Product: acetyl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MDSTAQIKRPKLAETVIHATASIRDSNIGRCCEVLADTSLHNVELGNYSYLGPRCMVGDAIIGKFCAIAAEVRIGAPNHP
MDRPSTHRFSYCPEYYAADAVRDDAFFAQRKQDRAIIGHDVWIGHGVIVLPGVTVGDGAVLAAGAVVTKDVPPYTIVGGV
PAKIIRERFSRSIAEKLAAIAWWDWPFETIMARLADFQSGDIEAFCERWS

Sequences:

>Translated_210_residues
MDSTAQIKRPKLAETVIHATASIRDSNIGRCCEVLADTSLHNVELGNYSYLGPRCMVGDAIIGKFCAIAAEVRIGAPNHP
MDRPSTHRFSYCPEYYAADAVRDDAFFAQRKQDRAIIGHDVWIGHGVIVLPGVTVGDGAVLAAGAVVTKDVPPYTIVGGV
PAKIIRERFSRSIAEKLAAIAWWDWPFETIMARLADFQSGDIEAFCERWS
>Mature_210_residues
MDSTAQIKRPKLAETVIHATASIRDSNIGRCCEVLADTSLHNVELGNYSYLGPRCMVGDAIIGKFCAIAAEVRIGAPNHP
MDRPSTHRFSYCPEYYAADAVRDDAFFAQRKQDRAIIGHDVWIGHGVIVLPGVTVGDGAVLAAGAVVTKDVPPYTIVGGV
PAKIIRERFSRSIAEKLAAIAWWDWPFETIMARLADFQSGDIEAFCERWS

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=130, Percent_Identity=34.6153846153846, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786537, Length=129, Percent_Identity=32.5581395348837, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788345, Length=133, Percent_Identity=30.0751879699248, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 22991; Mature: 22991

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTAQIKRPKLAETVIHATASIRDSNIGRCCEVLADTSLHNVELGNYSYLGPRCMVGDA
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCEEECCCCCEEHHH
IIGKFCAIAAEVRIGAPNHPMDRPSTHRFSYCPEYYAADAVRDDAFFAQRKQDRAIIGHD
HHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCE
VWIGHGVIVLPGVTVGDGAVLAAGAVVTKDVPPYTIVGGVPAKIIRERFSRSIAEKLAAI
EEECCCEEEECCEEECCCHHHHCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
AWWDWPFETIMARLADFQSGDIEAFCERWS
HHCCCCHHHHHHHHHCCCCCCHHHHHHCCC
>Mature Secondary Structure
MDSTAQIKRPKLAETVIHATASIRDSNIGRCCEVLADTSLHNVELGNYSYLGPRCMVGDA
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCEEECCCCCEEHHH
IIGKFCAIAAEVRIGAPNHPMDRPSTHRFSYCPEYYAADAVRDDAFFAQRKQDRAIIGHD
HHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCE
VWIGHGVIVLPGVTVGDGAVLAAGAVVTKDVPPYTIVGGVPAKIIRERFSRSIAEKLAAI
EEECCCEEEECCEEECCCHHHHCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
AWWDWPFETIMARLADFQSGDIEAFCERWS
HHCCCCHHHHHHHHHCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1314803 [H]