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The map label for this gene is moaE [H]

Identifier: 15888463

GI number: 15888463

Start: 1116007

End: 1116474

Strand: Reverse

Name: moaE [H]

Synonym: Atu1126

Alternate gene names: 15888463

Gene position: 1116474-1116007 (Counterclockwise)

Preceding gene: 159184626

Following gene: 17935031

Centisome position: 39.29

GC content: 61.75

Gene sequence:

>468_bases
ATGCAGAAAGTCGCTCAGCCGACGGTTCGCGTGCAGGCAGAAGACTTCGACGCCGCCGACGAAACACGCCTGTTGACCCA
GGGCGACAGAAGCATCGGCGCCGTCGTGGCCTTCACCGGGCTCTGCCGGGACGATGGCGGCACATTGACCGCACTGGAAC
TCGAACATTATCCCGGCATGGCGGAAGCGGAAATCACCCGCATCGCCAAACTGGCGATGGAGCGTTTCGGCCTGCTTGGC
CTCACCGCCATCCACCGCCATGGCAAGATCGCCACCGGCGAAAACATCGTCCTCGTCATTGCCGCCTCATCTCATCGACA
GGCCGCCTTCGATGGCGCCAGTTTCGTGATGGACTATCTCAAGACATCAGCCCCGTTCTGGAAAAAGGAACATGGCAGGG
ATGGCACGACGGGCGACTGGGTGGCAGCGAAGGCTACCGACGATACGGCCAGGGACAAGTGGCGATAG

Upstream 100 bases:

>100_bases
ATCAGGGTTGCCGTCAATCAGGAACATGTCGAGCATGACGAGAGCATTGTCGGCGCACGCGAGATCGGCATCTTCCCGCC
CATGACGGGAGGATGAGCGG

Downstream 100 bases:

>100_bases
CGCTTTTGTCTTATCGCATTTCCGGGCGGAAAACCGGGGCCCATTTTTCCCCCTAAGCTGCTTCAACCCGGCTGCGCATG
ACGATGAGCCAGCCAACCAG

Product: molybdopterin converting factor, large subunit

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MQKVAQPTVRVQAEDFDAADETRLLTQGDRSIGAVVAFTGLCRDDGGTLTALELEHYPGMAEAEITRIAKLAMERFGLLG
LTAIHRHGKIATGENIVLVIAASSHRQAAFDGASFVMDYLKTSAPFWKKEHGRDGTTGDWVAAKATDDTARDKWR

Sequences:

>Translated_155_residues
MQKVAQPTVRVQAEDFDAADETRLLTQGDRSIGAVVAFTGLCRDDGGTLTALELEHYPGMAEAEITRIAKLAMERFGLLG
LTAIHRHGKIATGENIVLVIAASSHRQAAFDGASFVMDYLKTSAPFWKKEHGRDGTTGDWVAAKATDDTARDKWR
>Mature_155_residues
MQKVAQPTVRVQAEDFDAADETRLLTQGDRSIGAVVAFTGLCRDDGGTLTALELEHYPGMAEAEITRIAKLAMERFGLLG
LTAIHRHGKIATGENIVLVIAASSHRQAAFDGASFVMDYLKTSAPFWKKEHGRDGTTGDWVAAKATDDTARDKWR

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=107, Percent_Identity=30.8411214953271, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787003, Length=153, Percent_Identity=41.1764705882353, Blast_Score=114, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21356259, Length=141, Percent_Identity=31.9148936170213, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16874; Mature: 16874

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVAQPTVRVQAEDFDAADETRLLTQGDRSIGAVVAFTGLCRDDGGTLTALELEHYPGM
CCCCCCCEEEEEECCCCCCCCCEEECCCCCCHHHHEEEEEEEECCCCEEEEEEECCCCCC
AEAEITRIAKLAMERFGLLGLTAIHRHGKIATGENIVLVIAASSHRQAAFDGASFVMDYL
CHHHHHHHHHHHHHHHCHHHHHHHHHCCCEECCCCEEEEEEECCCCCCHHCHHHHHHHHH
KTSAPFWKKEHGRDGTTGDWVAAKATDDTARDKWR
HCCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MQKVAQPTVRVQAEDFDAADETRLLTQGDRSIGAVVAFTGLCRDDGGTLTALELEHYPGM
CCCCCCCEEEEEECCCCCCCCCEEECCCCCCHHHHEEEEEEEECCCCEEEEEEECCCCCC
AEAEITRIAKLAMERFGLLGLTAIHRHGKIATGENIVLVIAASSHRQAAFDGASFVMDYL
CHHHHHHHHHHHHHHHCHHHHHHHHHCCCEECCCCEEEEEEECCCCCCHHCHHHHHHHHH
KTSAPFWKKEHGRDGTTGDWVAAKATDDTARDKWR
HCCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]