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The map label for this gene is nudF [H]

Identifier: 15888399

GI number: 15888399

Start: 1048544

End: 1048960

Strand: Reverse

Name: nudF [H]

Synonym: Atu1057

Alternate gene names: 15888399

Gene position: 1048960-1048544 (Counterclockwise)

Preceding gene: 159184597

Following gene: 159184595

Centisome position: 36.91

GC content: 61.63

Gene sequence:

>417_bases
ATGACCCTTCGTATCAAGCCCCGTGCCGCCTCCTCCGCCATCGTCAGGAATGGAGACCGGCTGCTTCTGGTGCGCCGTAT
CAACCCGCCCTCCAAGGACATGTTCGCCTTTCCCGGCGGACGGGCCGAAGAAGGGGAAACTCCGGACGAGACGGCATTGC
GCGAGCTGCACGAGGAAACCGGTATCATCGCCCGCAGGCCGCAGCTTTTCGCGACCTACGATCTTCCCACCCGTGACGCT
AAAGGCGTGCTGACGAGCCACTATTTCCTATCAGTCTTCACCGTGGAAACAGATGCAGATCCGCTGGTGACAGTGGGTGA
TGATGCGGCGGATGCGGGCTGGTACACCTTGGCGGAGATTCGCCTTCTGCCGGCGCCCGAAAGCGTTGTCGAATGTGCCG
AGCGCCTGCTTGCATGA

Upstream 100 bases:

>100_bases
GTTCCGGACTATAACCATCGGCGCGGAAACCGGAATCGATTTTTCCGAGTGACGACCACTATAGACAGGCCGGAAACGGC
CGAAACAAGCGAAACCATTC

Downstream 100 bases:

>100_bases
TTGCCAGCCAGCCAGAATCGCTATTATCTAGGACCGACCCGCCCGCCGGATGGTCACGAGCCAACAGTTCACGAGTATGT
GTGGGGCAGAATAGAATTTT

Product: ADP-ribose pyrophosphatase

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MTLRIKPRAASSAIVRNGDRLLLVRRINPPSKDMFAFPGGRAEEGETPDETALRELHEETGIIARRPQLFATYDLPTRDA
KGVLTSHYFLSVFTVETDADPLVTVGDDAADAGWYTLAEIRLLPAPESVVECAERLLA

Sequences:

>Translated_138_residues
MTLRIKPRAASSAIVRNGDRLLLVRRINPPSKDMFAFPGGRAEEGETPDETALRELHEETGIIARRPQLFATYDLPTRDA
KGVLTSHYFLSVFTVETDADPLVTVGDDAADAGWYTLAEIRLLPAPESVVECAERLLA
>Mature_137_residues
TLRIKPRAASSAIVRNGDRLLLVRRINPPSKDMFAFPGGRAEEGETPDETALRELHEETGIIARRPQLFATYDLPTRDAK
GVLTSHYFLSVFTVETDADPLVTVGDDAADAGWYTLAEIRLLPAPESVVECAERLLA

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: COG1051

COG function: function code F; ADP-ribose pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 15193; Mature: 15062

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRIKPRAASSAIVRNGDRLLLVRRINPPSKDMFAFPGGRAEEGETPDETALRELHEET
CEEEECCCCCCCCEEECCCEEEEEEECCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHC
GIIARRPQLFATYDLPTRDAKGVLTSHYFLSVFTVETDADPLVTVGDDAADAGWYTLAEI
CEEEECCCEEEEECCCCCCCCCEEEEEEEEEEEEEECCCCCEEEECCCCCCCCEEEEEEE
RLLPAPESVVECAERLLA
EEECCCHHHHHHHHHHCC
>Mature Secondary Structure 
TLRIKPRAASSAIVRNGDRLLLVRRINPPSKDMFAFPGGRAEEGETPDETALRELHEET
EEEECCCCCCCCEEECCCEEEEEEECCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHC
GIIARRPQLFATYDLPTRDAKGVLTSHYFLSVFTVETDADPLVTVGDDAADAGWYTLAEI
CEEEECCCEEEEECCCCCCCCCEEEEEEEEEEEEEECCCCCEEEECCCCCCCCEEEEEEE
RLLPAPESVVECAERLLA
EEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 9694840 [H]