Click here to switch to the map view.

The map label for this gene is gcvT [C]

Identifier: 15888395

GI number: 15888395

Start: 1045892

End: 1046740

Strand: Reverse

Name: gcvT [C]

Synonym: Atu1053

Alternate gene names: 15888395

Gene position: 1046740-1045892 (Counterclockwise)

Preceding gene: 15888396

Following gene: 159184594

Centisome position: 36.84

GC content: 63.6

Gene sequence:

>849_bases
ATGTCTTCCGCTTTTCTTGCCGACCGCCGCCTGATCCGGGTTTCCGGCACCGGCGCCGAAGAGTTTCTGAACAATCTGAT
CACGGCCGACATCGAAAATCTGCCGGAGGGCGAAACCCGTGCGTCGGCGCTTCTCACGCCGCAGGGCAAGATCCTGTTCG
ATTTCCTGATCTGGCGCGACGGTAGAGATTATCTTGTTGAAACGGGTGCCGCCGAACAGGATGCGCTGCTGCGCCGCCTG
ACCATGTACAAACTGCGCGCGCCCGTCGAGCTGAAAGCCGAGACCGTGGAAGGCATCGGCGTTTTCTGGGGGAACAGCGT
GACGGAGGCAGGCGTGCGGGATGGCCGTTTCGCCAAGGCGGGTGTCGATCTCCGGCGTGTGCCCGGCGCATCTGCCTCTG
GCGAGGCTGCGGCCTATGAGGCGCTGCGCGTCGAGCACGGCATTGCCGAATCCGGCCGGGATTATGCACTGCAGGACGCT
TTTCCCCATGATGTGCTGATGGATGTGAATGACGGCGTTTCCTTCAAGAAGGGCTGCTTCGTTGGCCAGGAAGTCGTTTC
CCGCATGAAACATCGCGGCACTGCAAGACGGCGCGTCGTGACCGTTTCGGCCGATGGCACGCTTCCCGCCAGCGGGACGG
AGATTACCGCCAATGGAAAACCCGTCGGTGCACTGGGAACCGTCTACGGCAACAGGGCCCTTGCCATTGTGCGGACCGAC
CGCGTTGCCGATGCGCTTGCCGCCGGCACGCCGCTTCTTGCCGACAATGTCGCGGTAAGCGTGGCCCTGCCAGCGTGGAG
CGGGCTTTCATTCCCGGCGGCCGATCCGGCGGCTCGGGCGGAGGACTAA

Upstream 100 bases:

>100_bases
CTCGGGTAAAAATCCTAACTGTGCGAAATGAGCATCCCGGGAAAGTGCATCTGCATTTTGCCTGATATCGCGCAGTCTCG
ATGAACCGAATGGTGACGCC

Downstream 100 bases:

>100_bases
GAGTGGCCCCCGCAAAAAGTCCGCGCGCCTGGCAGCGCATGCTGTCGGGACGACGGCTCGACCTGCTCGACCCTTCCCCG
CTCGATGTGGAAATTGCCGA

Product: glycine cleavage system T protein, aminomethyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSSAFLADRRLIRVSGTGAEEFLNNLITADIENLPEGETRASALLTPQGKILFDFLIWRDGRDYLVETGAAEQDALLRRL
TMYKLRAPVELKAETVEGIGVFWGNSVTEAGVRDGRFAKAGVDLRRVPGASASGEAAAYEALRVEHGIAESGRDYALQDA
FPHDVLMDVNDGVSFKKGCFVGQEVVSRMKHRGTARRRVVTVSADGTLPASGTEITANGKPVGALGTVYGNRALAIVRTD
RVADALAAGTPLLADNVAVSVALPAWSGLSFPAADPAARAED

Sequences:

>Translated_282_residues
MSSAFLADRRLIRVSGTGAEEFLNNLITADIENLPEGETRASALLTPQGKILFDFLIWRDGRDYLVETGAAEQDALLRRL
TMYKLRAPVELKAETVEGIGVFWGNSVTEAGVRDGRFAKAGVDLRRVPGASASGEAAAYEALRVEHGIAESGRDYALQDA
FPHDVLMDVNDGVSFKKGCFVGQEVVSRMKHRGTARRRVVTVSADGTLPASGTEITANGKPVGALGTVYGNRALAIVRTD
RVADALAAGTPLLADNVAVSVALPAWSGLSFPAADPAARAED
>Mature_281_residues
SSAFLADRRLIRVSGTGAEEFLNNLITADIENLPEGETRASALLTPQGKILFDFLIWRDGRDYLVETGAAEQDALLRRLT
MYKLRAPVELKAETVEGIGVFWGNSVTEAGVRDGRFAKAGVDLRRVPGASASGEAAAYEALRVEHGIAESGRDYALQDAF
PHDVLMDVNDGVSFKKGCFVGQEVVSRMKHRGTARRRVVTVSADGTLPASGTEITANGKPVGALGTVYGNRALAIVRTDR
VADALAAGTPLLADNVAVSVALPAWSGLSFPAADPAARAED

Specific function: Folate-binding protein involved in regulating the level of ATP-dnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication [H]

COG id: COG0354

COG function: function code R; Predicted aminomethyltransferase related to GcvT

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA-modifying ygfZ family [H]

Homologues:

Organism=Homo sapiens, GI58197556, Length=300, Percent_Identity=27.3333333333333, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71985951, Length=267, Percent_Identity=29.9625468164794, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017703
- InterPro:   IPR006222 [H]

Pfam domain/function: PF01571 GCV_T [H]

EC number: NA

Molecular weight: Translated: 29911; Mature: 29780

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAFLADRRLIRVSGTGAEEFLNNLITADIENLPEGETRASALLTPQGKILFDFLIWRD
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCCEEEEEEEEEC
GRDYLVETGAAEQDALLRRLTMYKLRAPVELKAETVEGIGVFWGNSVTEAGVRDGRFAKA
CCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEHCCEEEEEECCCCCCCCCCCCCEECC
GVDLRRVPGASASGEAAAYEALRVEHGIAESGRDYALQDAFPHDVLMDVNDGVSFKKGCF
CCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEECCCCCCHHHCCH
VGQEVVSRMKHRGTARRRVVTVSADGTLPASGTEITANGKPVGALGTVYGNRALAIVRTD
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCEEEEEECCEEEEEEECC
RVADALAAGTPLLADNVAVSVALPAWSGLSFPAADPAARAED
HHHHHHHCCCCEEECCEEEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSAFLADRRLIRVSGTGAEEFLNNLITADIENLPEGETRASALLTPQGKILFDFLIWRD
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCCEEEEEEEEEC
GRDYLVETGAAEQDALLRRLTMYKLRAPVELKAETVEGIGVFWGNSVTEAGVRDGRFAKA
CCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEHCCEEEEEECCCCCCCCCCCCCEECC
GVDLRRVPGASASGEAAAYEALRVEHGIAESGRDYALQDAFPHDVLMDVNDGVSFKKGCF
CCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEECCCCCCHHHCCH
VGQEVVSRMKHRGTARRRVVTVSADGTLPASGTEITANGKPVGALGTVYGNRALAIVRTD
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCEEEEEECCEEEEEEECC
RVADALAAGTPLLADNVAVSVALPAWSGLSFPAADPAARAED
HHHHHHHCCCCEEECCEEEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA