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The map label for this gene is ptrB [H]

Identifier: 15888236

GI number: 15888236

Start: 887372

End: 889471

Strand: Reverse

Name: ptrB [H]

Synonym: Atu0897

Alternate gene names: 15888236

Gene position: 889471-887372 (Counterclockwise)

Preceding gene: 159184523

Following gene: 159184521

Centisome position: 31.3

GC content: 59.67

Gene sequence:

>2100_bases
TTGCCTATTTTCAAGAACCTGCCCGCCGCTCCGACCGCCGAAAAACGGCCCGTCCAGGACACGCATCACGGCATCACCCG
CACCGACGACTACGCATGGTTCCGGGCCGATAACTGGCAGGCCATGTTCAAGGACCCCACCCTGCTCGACCCGGCCATTC
GCGCCCATCTGGAGGCGGAGAATGCCTATATGGAAGCCGCCATGGGCGACACCAGGGCGCTTCAGGAAAAGCTGTTCGAG
GAGATGAAGGGCCGCATCAAGCAGGACGATTCCTCCGTTCCGGTCAATGATGGGCCTTATGCCTACGGCACGCTGTTCGT
GACCGGCGGCGAGCAGCCGCATTATTTCCGCACCCCGCGTGATGGCGGCGACAAGCATGTGCTGCTGGATGGTGACAAGG
AAGCGCAAGGCAAGGATTATTTCCGTCTTGCCGGCCTCAACCAGTCGTCCGATCACAGTCACGGCATCTGGGGTTATGAC
GACAAGGGTTCGGAATATTTCACACTGCGCATCCGCAACCTCGAAACCGGTGAAGACCTTGCCGATGTCGTGGAAAATAC
CGGGGGCGGCGGTGCCTGGGCGCCTGACGGCAAGAGCTTCTTCTATACGCTGCAGGACGAGAACCACCGTCCGTCGAAAG
TCTTCCACCATATCATCGGCGAGCCGCAATCCGCCGACCGGCTGGTCTATGAGGAAAAGGACCCGGGTTTCTTCATGGGC
GTCGGAGCTTCTGTCCTCGACGATTTCATCTTCATCGATATTCACGACCATGAAACCAGCGAATACCGCATTCTTTCCAC
CAAAGACCTGACGGCTGAGCCAAAGGTGGTGGCGGAGCGCGAAGAGGGCATCGAATATTCGATGTGTGAAGGCGGCGACG
TCTTCTTCATCCTTACCAATGATGGTGACGCCAAGGATTTCCGCATCATGGAGGCGCCGGTTACCGCGCCGGGCAAGGAA
AACTGGAAAGAGGTGGTACCGCATGAGCCGGGCCGCCTCATTCTTTCCGTCGATGCCTATGCCCGCCATCTGATCTGGCT
GGAACGCCGCGACGGCCTGCCGCGCATCGTCATCCGCGATCGCCGCACAGGCGAGGAACATTCCATCGCCTTTGCCGAAG
AGGCCTATTCGCTTGGCCTGCACGGCGCGGCGGAATACGACACCGATGTCATCCGCTTCTCCTATTCCTCGATGACGACA
CCGAGCCAGCTGTTCGATTACAACATGGTGACGCGCGACCGCACGCTTCTGAAGACGCAGGAAGTACCATCAGGCCACAA
TCCTGATGACTACATCACCCGCCGCATCATGGCCCCTGCCCATGATGGCGAGCTGGTGCCGGTGTCCCTGCTCTACCGCA
AGGATGTGCCGCTCGACGGTTCCGCTCCCTGCCTGCTTTATGGTTATGGCGCTTACGGCATCACCATTCCCGCCTCCTTC
TCCACCACGACGCTATCTTTGGCCGACCGAGGTTTCATCTATGCCATCGCCCATATTCGCGGCGGCAAGGACAAGGGTTT
CGAATGGTACGAAACCGGCAAGATGGAAAACAAGCAGAACACGTTCAAGGATTTCATCGCGGCTGCCGATCATCTGGTTC
AGGAGGGTTTCACTTCCTATGAGGGCATCATCGCGGAAGGCGGTTCGGCGGGCGGCATGCTGATGGGTGCCGTCGCCAAT
ATGGCGCCAGAGAAATTCGCTGGCATCATCGCCGCCGTTCCCTTCGTGGACGTGCTGACGACCATGCTCGATGACACGCT
GCCGCTCACCCCGCCGGAATGGCCGGAATGGGGCAATCCGCTGGAATCGGAAGAGGAATATGGCTGGATCGCTGCCTACA
GCCCCTATGACAATGTCGGGGAAAAATCCTATCCGCCGCTGCTTGCGCTTTCCGGCCTCACAGACCCGCGCGTGACCTAT
TGGGAGCCGACCAAATGGGTGGCGAAGCTACGCGAGAAGACGACGGGGGAAGCCCCCATCCTGCTCAAGACCAACATGGC
GGCTGGCCATGGTGGCAAGTCGGGCCGTTTCCAGCGGCTGGAGGAAGTCGCCTTCGAATATGCCTTCGCCCTGAAGGTCG
CGGGCAAGGACGCCGTGTGA

Upstream 100 bases:

>100_bases
GCCTCATTTCCCCTGTTGAGATTTGAAACTTGATCGGGCGTGAGGGGCACTCTACATCTTGGTCCCGCCCATCGATTTTT
CATAGTAAAGCGAGTTTCCC

Downstream 100 bases:

>100_bases
CACGCTGAATGCAGAAACGGGCGGCGATCCAATCGTCGCCCGATCTTATTTTGGACGAAAATACCTGCAAAAATCTCGTT
TCTGAATATTTTTTCCACAA

Product: protease II

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 699; Mature: 698

Protein sequence:

>699_residues
MPIFKNLPAAPTAEKRPVQDTHHGITRTDDYAWFRADNWQAMFKDPTLLDPAIRAHLEAENAYMEAAMGDTRALQEKLFE
EMKGRIKQDDSSVPVNDGPYAYGTLFVTGGEQPHYFRTPRDGGDKHVLLDGDKEAQGKDYFRLAGLNQSSDHSHGIWGYD
DKGSEYFTLRIRNLETGEDLADVVENTGGGGAWAPDGKSFFYTLQDENHRPSKVFHHIIGEPQSADRLVYEEKDPGFFMG
VGASVLDDFIFIDIHDHETSEYRILSTKDLTAEPKVVAEREEGIEYSMCEGGDVFFILTNDGDAKDFRIMEAPVTAPGKE
NWKEVVPHEPGRLILSVDAYARHLIWLERRDGLPRIVIRDRRTGEEHSIAFAEEAYSLGLHGAAEYDTDVIRFSYSSMTT
PSQLFDYNMVTRDRTLLKTQEVPSGHNPDDYITRRIMAPAHDGELVPVSLLYRKDVPLDGSAPCLLYGYGAYGITIPASF
STTTLSLADRGFIYAIAHIRGGKDKGFEWYETGKMENKQNTFKDFIAAADHLVQEGFTSYEGIIAEGGSAGGMLMGAVAN
MAPEKFAGIIAAVPFVDVLTTMLDDTLPLTPPEWPEWGNPLESEEEYGWIAAYSPYDNVGEKSYPPLLALSGLTDPRVTY
WEPTKWVAKLREKTTGEAPILLKTNMAAGHGGKSGRFQRLEEVAFEYAFALKVAGKDAV

Sequences:

>Translated_699_residues
MPIFKNLPAAPTAEKRPVQDTHHGITRTDDYAWFRADNWQAMFKDPTLLDPAIRAHLEAENAYMEAAMGDTRALQEKLFE
EMKGRIKQDDSSVPVNDGPYAYGTLFVTGGEQPHYFRTPRDGGDKHVLLDGDKEAQGKDYFRLAGLNQSSDHSHGIWGYD
DKGSEYFTLRIRNLETGEDLADVVENTGGGGAWAPDGKSFFYTLQDENHRPSKVFHHIIGEPQSADRLVYEEKDPGFFMG
VGASVLDDFIFIDIHDHETSEYRILSTKDLTAEPKVVAEREEGIEYSMCEGGDVFFILTNDGDAKDFRIMEAPVTAPGKE
NWKEVVPHEPGRLILSVDAYARHLIWLERRDGLPRIVIRDRRTGEEHSIAFAEEAYSLGLHGAAEYDTDVIRFSYSSMTT
PSQLFDYNMVTRDRTLLKTQEVPSGHNPDDYITRRIMAPAHDGELVPVSLLYRKDVPLDGSAPCLLYGYGAYGITIPASF
STTTLSLADRGFIYAIAHIRGGKDKGFEWYETGKMENKQNTFKDFIAAADHLVQEGFTSYEGIIAEGGSAGGMLMGAVAN
MAPEKFAGIIAAVPFVDVLTTMLDDTLPLTPPEWPEWGNPLESEEEYGWIAAYSPYDNVGEKSYPPLLALSGLTDPRVTY
WEPTKWVAKLREKTTGEAPILLKTNMAAGHGGKSGRFQRLEEVAFEYAFALKVAGKDAV
>Mature_698_residues
PIFKNLPAAPTAEKRPVQDTHHGITRTDDYAWFRADNWQAMFKDPTLLDPAIRAHLEAENAYMEAAMGDTRALQEKLFEE
MKGRIKQDDSSVPVNDGPYAYGTLFVTGGEQPHYFRTPRDGGDKHVLLDGDKEAQGKDYFRLAGLNQSSDHSHGIWGYDD
KGSEYFTLRIRNLETGEDLADVVENTGGGGAWAPDGKSFFYTLQDENHRPSKVFHHIIGEPQSADRLVYEEKDPGFFMGV
GASVLDDFIFIDIHDHETSEYRILSTKDLTAEPKVVAEREEGIEYSMCEGGDVFFILTNDGDAKDFRIMEAPVTAPGKEN
WKEVVPHEPGRLILSVDAYARHLIWLERRDGLPRIVIRDRRTGEEHSIAFAEEAYSLGLHGAAEYDTDVIRFSYSSMTTP
SQLFDYNMVTRDRTLLKTQEVPSGHNPDDYITRRIMAPAHDGELVPVSLLYRKDVPLDGSAPCLLYGYGAYGITIPASFS
TTTLSLADRGFIYAIAHIRGGKDKGFEWYETGKMENKQNTFKDFIAAADHLVQEGFTSYEGIIAEGGSAGGMLMGAVANM
APEKFAGIIAAVPFVDVLTTMLDDTLPLTPPEWPEWGNPLESEEEYGWIAAYSPYDNVGEKSYPPLLALSGLTDPRVTYW
EPTKWVAKLREKTTGEAPILLKTNMAAGHGGKSGRFQRLEEVAFEYAFALKVAGKDAV

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=592, Percent_Identity=27.5337837837838, Blast_Score=209, Evalue=7e-54,
Organism=Homo sapiens, GI284172420, Length=473, Percent_Identity=28.5412262156448, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI284172413, Length=473, Percent_Identity=28.5412262156448, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI70778815, Length=473, Percent_Identity=28.5412262156448, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI284172438, Length=473, Percent_Identity=28.5412262156448, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI284172431, Length=473, Percent_Identity=28.5412262156448, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI108860686, Length=245, Percent_Identity=35.5102040816327, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI108860692, Length=222, Percent_Identity=36.036036036036, Blast_Score=131, Evalue=2e-30,
Organism=Escherichia coli, GI1788150, Length=688, Percent_Identity=38.6627906976744, Blast_Score=456, Evalue=1e-129,
Organism=Drosophila melanogaster, GI24583414, Length=588, Percent_Identity=26.1904761904762, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI221510989, Length=609, Percent_Identity=25.2873563218391, Blast_Score=176, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 77899; Mature: 77768

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00708 PRO_ENDOPEP_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIFKNLPAAPTAEKRPVQDTHHGITRTDDYAWFRADNWQAMFKDPTLLDPAIRAHLEAE
CCCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHH
NAYMEAAMGDTRALQEKLFEEMKGRIKQDDSSVPVNDGPYAYGTLFVTGGEQPHYFRTPR
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEECCC
DGGDKHVLLDGDKEAQGKDYFRLAGLNQSSDHSHGIWGYDDKGSEYFTLRIRNLETGEDL
CCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHH
ADVVENTGGGGAWAPDGKSFFYTLQDENHRPSKVFHHIIGEPQSADRLVYEEKDPGFFMG
HHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCEEEE
VGASVLDDFIFIDIHDHETSEYRILSTKDLTAEPKVVAEREEGIEYSMCEGGDVFFILTN
CCHHHHCCEEEEEEECCCCCCEEEEECCCCCCCCCEEEEHHCCCEEEEECCCCEEEEEEC
DGDAKDFRIMEAPVTAPGKENWKEVVPHEPGRLILSVDAYARHLIWLERRDGLPRIVIRD
CCCCCCEEEEECCCCCCCCCCHHHCCCCCCCEEEEEECHHHEEEEEEECCCCCCEEEEEC
RRTGEEHSIAFAEEAYSLGLHGAAEYDTDVIRFSYSSMTTPSQLFDYNMVTRDRTLLKTQ
CCCCCCCCEEEHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHCCCHHHCCCHHHEEC
EVPSGHNPDDYITRRIMAPAHDGELVPVSLLYRKDVPLDGSAPCLLYGYGAYGITIPASF
CCCCCCCCHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEECCEEEEEECCC
STTTLSLADRGFIYAIAHIRGGKDKGFEWYETGKMENKQNTFKDFIAAADHLVQEGFTSY
CEEEEEECCCCEEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCC
EGIIAEGGSAGGMLMGAVANMAPEKFAGIIAAVPFVDVLTTMLDDTLPLTPPEWPEWGNP
CCEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
LESEEEYGWIAAYSPYDNVGEKSYPPLLALSGLTDPRVTYWEPTKWVAKLREKTTGEAPI
CCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCEEEECCHHHHHHHHHHCCCCCCE
LLKTNMAAGHGGKSGRFQRLEEVAFEYAFALKVAGKDAV
EEEECCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCC
>Mature Secondary Structure 
PIFKNLPAAPTAEKRPVQDTHHGITRTDDYAWFRADNWQAMFKDPTLLDPAIRAHLEAE
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHH
NAYMEAAMGDTRALQEKLFEEMKGRIKQDDSSVPVNDGPYAYGTLFVTGGEQPHYFRTPR
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEECCC
DGGDKHVLLDGDKEAQGKDYFRLAGLNQSSDHSHGIWGYDDKGSEYFTLRIRNLETGEDL
CCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHH
ADVVENTGGGGAWAPDGKSFFYTLQDENHRPSKVFHHIIGEPQSADRLVYEEKDPGFFMG
HHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCEEEE
VGASVLDDFIFIDIHDHETSEYRILSTKDLTAEPKVVAEREEGIEYSMCEGGDVFFILTN
CCHHHHCCEEEEEEECCCCCCEEEEECCCCCCCCCEEEEHHCCCEEEEECCCCEEEEEEC
DGDAKDFRIMEAPVTAPGKENWKEVVPHEPGRLILSVDAYARHLIWLERRDGLPRIVIRD
CCCCCCEEEEECCCCCCCCCCHHHCCCCCCCEEEEEECHHHEEEEEEECCCCCCEEEEEC
RRTGEEHSIAFAEEAYSLGLHGAAEYDTDVIRFSYSSMTTPSQLFDYNMVTRDRTLLKTQ
CCCCCCCCEEEHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHCCCHHHCCCHHHEEC
EVPSGHNPDDYITRRIMAPAHDGELVPVSLLYRKDVPLDGSAPCLLYGYGAYGITIPASF
CCCCCCCCHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEECCEEEEEECCC
STTTLSLADRGFIYAIAHIRGGKDKGFEWYETGKMENKQNTFKDFIAAADHLVQEGFTSY
CEEEEEECCCCEEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCC
EGIIAEGGSAGGMLMGAVANMAPEKFAGIIAAVPFVDVLTTMLDDTLPLTPPEWPEWGNP
CCEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
LESEEEYGWIAAYSPYDNVGEKSYPPLLALSGLTDPRVTYWEPTKWVAKLREKTTGEAPI
CCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCEEEECCHHHHHHHHHHCCCCCCE
LLKTNMAAGHGGKSGRFQRLEEVAFEYAFALKVAGKDAV
EEEECCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]