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The map label for this gene is coxC [H]

Identifier: 15888114

GI number: 15888114

Start: 767408

End: 768283

Strand: Direct

Name: coxC [H]

Synonym: Atu0771

Alternate gene names: 15888114

Gene position: 767408-768283 (Clockwise)

Preceding gene: 15888113

Following gene: 159184459

Centisome position: 27.01

GC content: 58.33

Gene sequence:

>876_bases
ATGGCAGACACGCATCAGAAGAACCACGATTACCACATCATAGACCCGAGCCCGTGGCCGCTTCTGGCCTCCATCGGCGC
CTTCATCATGACTTTCGGCGGCGTCTGCTACATGCGTTACCTGTCGGGCGGCTCCTTCAAGCTGTTCGGTGCGGAACTGG
CCAACCCCTGGCTGTTCTATATCGGTCTCGTCATCGTGCTTTACGTCATGTACGCCTGGTGGGCGGACACGATCAAGGAA
GCCAATGAGGGCAGCCATACCCGCGTGGTTTCGCTGCATCTGCGTTACGGCATGATCATGTTCATCGCCTCCGAGGTGAT
GTTCTTTGTCGCCTGGTTCTGGGCCTATTTCGATGCCAGCCTCTTCCCGCATGAGGCCATTCAGGCGTCGCGCCTCGAAT
ATACCGGCGGTCAATGGCCACCGAAGGGCATCGAGGTCATCGATCCCTGGCATCTGCCGCTCTACAACACCGTCATCCTG
CTTCTCTCGGGCACCTGCGTCACCTGGGCGCACCATGCCCTGCTGCATAATGATCGCAAGGGCCTGATCTCGGGTCTGGC
ATTGACCGTCGCGCTCGGCGTCCTGTTCTCCACCGTGCAGGTTTACGAATACATTCACGCACCATTCGACTTCAAGAATT
CGATCTACGGCGCTACCTTCTTCATGGCCACCGGTTTCCACGGTTTCCATGTCTTCGTCGGCACTGTCTTCCTGCTGGTC
TGCCTGTTCCGCGCCATCGCCGGCGGTTTCACACCCAAACAGCATTTCGGTTTCGAAGCGGCCGCCTGGTATTGGCACTT
CGTTGACGTCGTCTGGCTGTTCCTGTTCTTCGCCATCTATATCTGGGGTGGCTGGGGCGCACCGCTGCACGGTTAA

Upstream 100 bases:

>100_bases
TTGCCGGTAAAGACAGAATCTGGCGACAGCAAATTGTAAGAGGAGATCCGGGTCTTTTGAGGGGGCCGGATCAGGGAAGA
GATAGCAGGGGATTGTCGCA

Downstream 100 bases:

>100_bases
CTTACGCCGTGTAGCCCACCACGTTGCTTCTGAGATGAGCGAGCGCCACGTATTTCTTCTCCCCGCCGGGGAGAAGGTCG
CGGCAGCGGGACGAGGCGGC

Product: cytochrome c oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MADTHQKNHDYHIIDPSPWPLLASIGAFIMTFGGVCYMRYLSGGSFKLFGAELANPWLFYIGLVIVLYVMYAWWADTIKE
ANEGSHTRVVSLHLRYGMIMFIASEVMFFVAWFWAYFDASLFPHEAIQASRLEYTGGQWPPKGIEVIDPWHLPLYNTVIL
LLSGTCVTWAHHALLHNDRKGLISGLALTVALGVLFSTVQVYEYIHAPFDFKNSIYGATFFMATGFHGFHVFVGTVFLLV
CLFRAIAGGFTPKQHFGFEAAAWYWHFVDVVWLFLFFAIYIWGGWGAPLHG

Sequences:

>Translated_291_residues
MADTHQKNHDYHIIDPSPWPLLASIGAFIMTFGGVCYMRYLSGGSFKLFGAELANPWLFYIGLVIVLYVMYAWWADTIKE
ANEGSHTRVVSLHLRYGMIMFIASEVMFFVAWFWAYFDASLFPHEAIQASRLEYTGGQWPPKGIEVIDPWHLPLYNTVIL
LLSGTCVTWAHHALLHNDRKGLISGLALTVALGVLFSTVQVYEYIHAPFDFKNSIYGATFFMATGFHGFHVFVGTVFLLV
CLFRAIAGGFTPKQHFGFEAAAWYWHFVDVVWLFLFFAIYIWGGWGAPLHG
>Mature_290_residues
ADTHQKNHDYHIIDPSPWPLLASIGAFIMTFGGVCYMRYLSGGSFKLFGAELANPWLFYIGLVIVLYVMYAWWADTIKEA
NEGSHTRVVSLHLRYGMIMFIASEVMFFVAWFWAYFDASLFPHEAIQASRLEYTGGQWPPKGIEVIDPWHLPLYNTVILL
LSGTCVTWAHHALLHNDRKGLISGLALTVALGVLFSTVQVYEYIHAPFDFKNSIYGATFFMATGFHGFHVFVGTVFLLVC
LFRAIAGGFTPKQHFGFEAAAWYWHFVDVVWLFLFFAIYIWGGWGAPLHG

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=282, Percent_Identity=45.7446808510638, Blast_Score=234, Evalue=7e-62,
Organism=Escherichia coli, GI1786633, Length=141, Percent_Identity=31.2056737588652, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6226542, Length=284, Percent_Identity=34.1549295774648, Blast_Score=168, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 33074; Mature: 32943

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTHQKNHDYHIIDPSPWPLLASIGAFIMTFGGVCYMRYLSGGSFKLFGAELANPWLFY
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHCCHHHHH
IGLVIVLYVMYAWWADTIKEANEGSHTRVVSLHLRYGMIMFIASEVMFFVAWFWAYFDAS
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LFPHEAIQASRLEYTGGQWPPKGIEVIDPWHLPLYNTVILLLSGTCVTWAHHALLHNDRK
CCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHH
GLISGLALTVALGVLFSTVQVYEYIHAPFDFKNSIYGATFFMATGFHGFHVFVGTVFLLV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
CLFRAIAGGFTPKQHFGFEAAAWYWHFVDVVWLFLFFAIYIWGGWGAPLHG
HHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ADTHQKNHDYHIIDPSPWPLLASIGAFIMTFGGVCYMRYLSGGSFKLFGAELANPWLFY
CCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHCCHHHHH
IGLVIVLYVMYAWWADTIKEANEGSHTRVVSLHLRYGMIMFIASEVMFFVAWFWAYFDAS
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LFPHEAIQASRLEYTGGQWPPKGIEVIDPWHLPLYNTVILLLSGTCVTWAHHALLHNDRK
CCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHH
GLISGLALTVALGVLFSTVQVYEYIHAPFDFKNSIYGATFFMATGFHGFHVFVGTVFLLV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
CLFRAIAGGFTPKQHFGFEAAAWYWHFVDVVWLFLFFAIYIWGGWGAPLHG
HHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]