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The map label for this gene is kdtA [H]

Identifier: 15888039

GI number: 15888039

Start: 693451

End: 694773

Strand: Direct

Name: kdtA [H]

Synonym: Atu0695

Alternate gene names: 15888039

Gene position: 693451-694773 (Clockwise)

Preceding gene: 15888038

Following gene: 15888040

Centisome position: 24.4

GC content: 61.98

Gene sequence:

>1323_bases
ATGAGCAGCCGTCTCGCACGCTTCGCTCTTTCGGGTTACCGGATCGCCGGTATCGCCGCCTATCCCTTTGCCAGACCCTA
CCTTTCTTATCGGGCGGCAAAAGGCAAGGAAGACAAGCGCCGCCGGCTTGAACGTTTCGGTTACGCCAGCGCCGAGCGCC
CGCGTGGCCCGCTCGTCTGGTTCCATGCTGCAAGTGTTGGCGAAACCCTTGCCCTCATCCCGCTGATCCGCGAAATCCGC
AAGCGCGATATCTTCGTGCTTCTGACCACCGGCACCGTCACCTCCGCTGAACTGACCCGCACCCGGCTTGGCGACGACGT
GATCCACCAATATGTGCCGCTCGACATCAAGATCGCGGTCAACCGTTTCCTGACCTATTGGGCGCCGGATGCGGCCATAA
CGGCGGAATCGGAAATCTGGCCGGTGACGATGATGGAACTGGAGCGTCGGCACATCCCGCAGATAAGGGTCAATGCGCGC
CTTTCCGATCGTTCCTTCGACCGCTGGAAAGCCCGCCACGACATTGCGGAATCGCTGTTTTCCAAGCTGGCGCTGGTGGT
CGCGCAGTCCGATCTCGATGCCGAACGTTTCCGCGATCTCGGCTCCTGGCCGGTGGTGATTTCGGGCAACCTCAAGGGTG
ACACCGACCCGCCGCCCTGCGACGAGGCGCTACTGGAGAGCTATCGCAAACAGGTCGGCAATCGCAAGACATGGGCGGCG
ATCTCCACTTTCGACGGCGAGGAGAAGGCAGCCGCTACAGTTCACGCGGCGATCAAGTCGCGCAACGGCCAGCTGACCAT
CATCGTGCCGCGCCATCCTGAGCGTGGCGATGATGTGGAGGCCATGCTGAAGGGCATGAACCTTTCCGTCGCCCGCCGCA
GCCGCAATGATGTGATCACCCCGGGAACCGATATTTTCCTCGGCGATTCCATCGGCGAAATGGGGCTTTACCTGCGGCTG
ACCGAACTTGCCTTTGTCGGCCGCTCGCTGACGGCCGAGGGCGGGCAGAACCCGCTGGAGCCGGCCATGCTCGGCTGCGC
CGTATTGTCGGGTGCCCATGTGCAGAATTTCCGCGAGGCCTATCAGAAGCTGATTCGCGCCGGCGGTGGTCGCATCATCC
GTGATGTCGAGATGCTGGCCAAGGCGGTGCATTATCTCTTGGTCAACGACAATGAGCGGTACAAGATGATCGACGCCGGC
AACCGGGTCATTCAGGATATGCGCGGCGCGCTCTCCTCCACCGTCAAGGCGCTGGAGCCCTATATCAACCCGCTCACCGT
TTCGGCCAAGCTGCAACCGCGGAGCGCCATCGGTTCATGGTAG

Upstream 100 bases:

>100_bases
TTTGCCATGACAAAAAATGACGCAATTTAAGAAGAAGTAGGCGGCGACAACAACAAGAACAGGGGCAGGCATTGCGCGGA
ATGATCAAGGACAGAATGTC

Downstream 100 bases:

>100_bases
CGGATATCGAACTTGATGCGGCACAGTCGATCGCCGCTGTGCTCTTCGACAAGGACGGCACGCTGTTAGGTTACGACGCG
AGCTGGGGACCGGTAAACCG

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSSRLARFALSGYRIAGIAAYPFARPYLSYRAAKGKEDKRRRLERFGYASAERPRGPLVWFHAASVGETLALIPLIREIR
KRDIFVLLTTGTVTSAELTRTRLGDDVIHQYVPLDIKIAVNRFLTYWAPDAAITAESEIWPVTMMELERRHIPQIRVNAR
LSDRSFDRWKARHDIAESLFSKLALVVAQSDLDAERFRDLGSWPVVISGNLKGDTDPPPCDEALLESYRKQVGNRKTWAA
ISTFDGEEKAAATVHAAIKSRNGQLTIIVPRHPERGDDVEAMLKGMNLSVARRSRNDVITPGTDIFLGDSIGEMGLYLRL
TELAFVGRSLTAEGGQNPLEPAMLGCAVLSGAHVQNFREAYQKLIRAGGGRIIRDVEMLAKAVHYLLVNDNERYKMIDAG
NRVIQDMRGALSSTVKALEPYINPLTVSAKLQPRSAIGSW

Sequences:

>Translated_440_residues
MSSRLARFALSGYRIAGIAAYPFARPYLSYRAAKGKEDKRRRLERFGYASAERPRGPLVWFHAASVGETLALIPLIREIR
KRDIFVLLTTGTVTSAELTRTRLGDDVIHQYVPLDIKIAVNRFLTYWAPDAAITAESEIWPVTMMELERRHIPQIRVNAR
LSDRSFDRWKARHDIAESLFSKLALVVAQSDLDAERFRDLGSWPVVISGNLKGDTDPPPCDEALLESYRKQVGNRKTWAA
ISTFDGEEKAAATVHAAIKSRNGQLTIIVPRHPERGDDVEAMLKGMNLSVARRSRNDVITPGTDIFLGDSIGEMGLYLRL
TELAFVGRSLTAEGGQNPLEPAMLGCAVLSGAHVQNFREAYQKLIRAGGGRIIRDVEMLAKAVHYLLVNDNERYKMIDAG
NRVIQDMRGALSSTVKALEPYINPLTVSAKLQPRSAIGSW
>Mature_439_residues
SSRLARFALSGYRIAGIAAYPFARPYLSYRAAKGKEDKRRRLERFGYASAERPRGPLVWFHAASVGETLALIPLIREIRK
RDIFVLLTTGTVTSAELTRTRLGDDVIHQYVPLDIKIAVNRFLTYWAPDAAITAESEIWPVTMMELERRHIPQIRVNARL
SDRSFDRWKARHDIAESLFSKLALVVAQSDLDAERFRDLGSWPVVISGNLKGDTDPPPCDEALLESYRKQVGNRKTWAAI
STFDGEEKAAATVHAAIKSRNGQLTIIVPRHPERGDDVEAMLKGMNLSVARRSRNDVITPGTDIFLGDSIGEMGLYLRLT
ELAFVGRSLTAEGGQNPLEPAMLGCAVLSGAHVQNFREAYQKLIRAGGGRIIRDVEMLAKAVHYLLVNDNERYKMIDAGN
RVIQDMRGALSSTVKALEPYINPLTVSAKLQPRSAIGSW

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers a single molecule of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=403, Percent_Identity=36.4764267990074, Blast_Score=229, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 49039; Mature: 48908

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRLARFALSGYRIAGIAAYPFARPYLSYRAAKGKEDKRRRLERFGYASAERPRGPLVW
CCCHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEE
FHAASVGETLALIPLIREIRKRDIFVLLTTGTVTSAELTRTRLGDDVIHQYVPLDIKIAV
EECCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCHHHHHHHCCCEEEEEH
NRFLTYWAPDAAITAESEIWPVTMMELERRHIPQIRVNARLSDRSFDRWKARHDIAESLF
HHHHHHCCCCCEEECCCCCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHH
SKLALVVAQSDLDAERFRDLGSWPVVISGNLKGDTDPPPCDEALLESYRKQVGNRKTWAA
HHHHHHHHCCCCCHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEE
ISTFDGEEKAAATVHAAIKSRNGQLTIIVPRHPERGDDVEAMLKGMNLSVARRSRNDVIT
EEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHCCCCCEEECCCCCCCCC
PGTDIFLGDSIGEMGLYLRLTELAFVGRSLTAEGGQNPLEPAMLGCAVLSGAHVQNFREA
CCCCEEECCCCCHHHHHEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
YQKLIRAGGGRIIRDVEMLAKAVHYLLVNDNERYKMIDAGNRVIQDMRGALSSTVKALEP
HHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
YINPLTVSAKLQPRSAIGSW
CCCCEEEEEEECCHHCCCCC
>Mature Secondary Structure 
SSRLARFALSGYRIAGIAAYPFARPYLSYRAAKGKEDKRRRLERFGYASAERPRGPLVW
CCHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEE
FHAASVGETLALIPLIREIRKRDIFVLLTTGTVTSAELTRTRLGDDVIHQYVPLDIKIAV
EECCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCHHHHHHHCCCEEEEEH
NRFLTYWAPDAAITAESEIWPVTMMELERRHIPQIRVNARLSDRSFDRWKARHDIAESLF
HHHHHHCCCCCEEECCCCCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHH
SKLALVVAQSDLDAERFRDLGSWPVVISGNLKGDTDPPPCDEALLESYRKQVGNRKTWAA
HHHHHHHHCCCCCHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEE
ISTFDGEEKAAATVHAAIKSRNGQLTIIVPRHPERGDDVEAMLKGMNLSVARRSRNDVIT
EEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHCCCCCEEECCCCCCCCC
PGTDIFLGDSIGEMGLYLRLTELAFVGRSLTAEGGQNPLEPAMLGCAVLSGAHVQNFREA
CCCCEEECCCCCHHHHHEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
YQKLIRAGGGRIIRDVEMLAKAVHYLLVNDNERYKMIDAGNRVIQDMRGALSSTVKALEP
HHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
YINPLTVSAKLQPRSAIGSW
CCCCEEEEEEECCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952982; 7542800 [H]